Results 41 to 50 of about 17,237 (190)

Fundus autofluorescence applications in retinal imaging

Indian Journal of Ophthalmology, 2015
Fundus autofluorescence (FAF) is a relatively new imaging technique that can be used to study retinal diseases. It provides information on retinal metabolism and health. Several different pathologies can be detected.
Andrea Gabai, Daniele Veritti, Paolo Lanzetta   +2 more
doaj   +1 more source

Anti-aging Effects and Mechanisms of Recombinant Human-derived Collagen on Aging Mouse Induced by D-Galactose

Shipin gongye ke-ji, 2023
In order to explore the anti-aging effect and mechanism of recombinant recombinant human-derived collagen (RHC), the aging mouse model was constructed through 300 mg/kg D-galactose intraperitoneal injection, and different doses of RHC were used to study ...
Jia LI, Miaoqing AN, Chenhao LÜ, Rongxiang GUO, Bing DU, Qing HE   +5 more
doaj   +1 more source

Temporary Vitelliform Regression After Intravitreal Ranibizumab Injection for Macular Neovascularization Complicating Best Disease

International Medical Case Reports Journal, 2022
Alaa Fayed1,2 1Department of Ophthalmology, Kasr Al-Ainy School of Medicine, Cairo University, Giza, Egypt; 2Watany Research and Development Center, Watany Eye Hospital, Cairo, EgyptCorrespondence: Alaa Fayed, Department of Ophthalmology, Kasr Al-Ainy ...
Fayed A
doaj  

Crosstalk between the Rod Outer Segments and Retinal Pigmented Epithelium in the Generation of Oxidative Stress in an In Vitro Model

Cells, 2023
Dysfunction of the retinal pigment epithelium (RPE) is associated with several diseases characterized by retinal degeneration, such as diabetic retinopathy (DR).
Silvia Ravera, Nadia Bertola, Alessandra Puddu, Silvia Bruno, Davide Maggi, Isabella Panfoli   +5 more
doaj   +1 more source

Lipofuscin: The Missing Link in the Worsening of Obstructive Sleep Apnea

The Laryngoscope, EarlyView.
Lipofuscin, also known as the age pigment, is a permanent autofluorescent intracellular deposit that accumulates with aging or oxidative stress, thereby interfering with cellular function. This study revealed significantly larger deposits of lipofuscin in the lateral pharyngeal wall muscles of patients with severe obstructive sleep apnea (OSA) compared
Kristine Fahl, Carlos Modesto Vera Palomino, Mauricio da Silva Baptista, Adriano Polican Ciena, Danielle Andrade da Silva Dantas, Luiz Ubirajara Sennes, Marucia Chacur, Michel Burihan Cahali   +7 more
wiley   +1 more source

Oxidized protein aggregate lipofuscin impairs cardiomyocyte contractility via late-stage autophagy inhibition

Redox Biology
Aging of the heart is accompanied by impairment of cardiac structure and function. At molecular level, autophagy plays a crucial role in preserving cardiac health.
Sophia Walter, Steffen P. Häseli, Patricia Baumgarten, Stefanie Deubel, Tobias Jung, Annika Höhn, Christiane Ott, Tilman Grune   +7 more
doaj   +1 more source

Macular edema in Asian Indian premature infants with retinopathy of prematurity: Impact on visual acuity and refractive status after 1-year

Indian Journal of Ophthalmology, 2015
Purpose: To report the impact of transient, self-resolving, untreated "macular edema" detected on spectral domain optical coherence tomography in Asian Indian premature infants with retinopathy of prematurity (ROP) on visual acuity (VA) and refraction at
Anand Vinekar, Shwetha Mangalesh, Chaitra Jayadev, Noel Bauer, Sivakumar Munusamy, Vasudha Kemmanu, Mathew Kurian, Padmamalini Mahendradas, Kavitha Avadhani, Bhujang Shetty   +9 more
doaj   +1 more source

Exploring the Impact of Polystyrene Microplastic Beads on Male Gonads of the Marine Mussel, Mytilus galloprovincialis

Environmental Toxicology, EarlyView.
ABSTRACT Plastic, with its remarkable versatility and numerous applications, has greatly benefited humanity. However, its extreme resistance to natural degradation means it persists in the environment for long periods, causing global environmental problems.
Teresa Chianese, Mariachiara Galati, Tiziana Cappello, Maria Maisano, Gennaro Lettieri, Carmela Marinaro, Marina Piscopo, Gianluca Fasciolo, Carlos Gravato, Gaetana Napolitano, Giulia Paolella, Annamaria Locascio, Rosaria Scudiero, Luigi Rosati   +13 more
wiley   +1 more source

Neovascular age‐related macular degeneration without drusen

Acta Ophthalmologica, EarlyView.
Abstract Purpose To describe the clinical characteristics and 1‐year follow‐up of patients with neovascular AMD (nAMD) without drusen in either eye. Methods This is a multicentre retrospective cohort study in three tertiary referral centres in The Netherlands. We included patients of 55 years or older with nAMD in one or both eyes, without the presence
Marc J. Sirks, Elon H. C. van Dijk, Husein Ghalayini, Somayeh Bazdar, WeiFeng Yu, Suzanne Yzer, José P. Martinez Ciriano, Reinier O. Schlingemann, Roselie M. H. Diederen, Camiel J. F. Boon   +9 more
wiley   +1 more source

β‐Secretase (BACE1) inhibition causes retinal pathology by vascular dysregulation and accumulation of age pigment

EMBO Molecular Medicine, 2012
β‐Secretase (BACE1) is a major drug target for combating Alzheimer's disease (AD). Here we show that BACE1−/− mice develop significant retinal pathology including retinal thinning, apoptosis, reduced retinal vascular density and an increase in the age ...
Jun Cai, Xiaoping Qi, Norbert Kociok, Sergej Skosyrski, Alonso Emilio, Qing Ruan, Song Han, Li Liu, Zhijuan Chen, Catherine Bowes Rickman, Todd Golde, Maria B. Grant, Paul Saftig, Lutgarde Serneels, Bart de Strooper, Antonia M. Joussen, Michael E. Boulton   +16 more
doaj   +1 more source