Results 121 to 130 of about 77,919 (340)

Stimulatory Effects of Cinnamon Extract (Cinnamomum cassia) during the Initiation Stage of 3T3-L1 Adipocyte Differentiation

open access: yesFoods, 2016
Cinnamon (Cinnamomum cassia) has an anti-diabetic effect by possibly increasing the lipid storage capacity of white adipocytes; however, this effect remains controversial.
Sang Gil Lee   +2 more
doaj   +1 more source

Untargeted Metabolomics Identifies N‐Lactoyl‐Amino Acids as Dose‐Responsive Plasma Biomarkers of Metformin Adherence in Type 2 Diabetes

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Metformin is the most widely prescribed antidiabetic drug, yet adherence remains difficult to objectively assess. Using untargeted metabolomics and lipidomics, we analyzed plasma from 637 patients with type 2 diabetes (T2D) with confirmed metformin use and 143 nondiabetic controls, annotating 614 metabolites.
Tomas Cajka   +12 more
wiley   +1 more source

Inactivation of mitochondrial MUL1 E3 ubiquitin ligase deregulates mitophagy and prevents diet-induced obesity in mice

open access: yesFrontiers in Molecular Biosciences
Obesity is a growing epidemic affecting millions of people worldwide and a major risk factor for a multitude of chronic diseases and premature mortality.
Lucia Cilenti   +7 more
doaj   +1 more source

Improved techniques for studies of adipocyte cellularity and metabolism1

open access: yesJournal of Lipid Research, 1977
Two methods are described for the study of adipose tissue cellularity and metabolism. In the first, 8 M urea was used to liberate osmium tetroxide-fixed adipocytes from the connective tissue matrix.
T D Etherton, E H Thompson, C E Allen
doaj   +1 more source

Computer‐Aided Functional Oligosaccharide Screening and the Regulatory Role in Lipid Metabolism

open access: yesFood Bioengineering, EarlyView.
ABSTRACT This study investigated the lipid‐lowering effects and intervention mechanisms of structurally diverse functional oligosaccharides on non‐alcoholic fatty liver disease (NAFLD). By integrating computational tools such as molecular docking and molecular dynamics simulations (MDS), a comprehensive “in silico‐in vitro‐in vivo” tri‐dimensional ...
Rui Jing   +3 more
wiley   +1 more source

Lipogenesis in rabbit adipose tissue

open access: yesJournal of Lipid Research, 1975
Previous reports that rabbit adipose tissue does not synthesize fatty acids at significant rates led us to study in detail the pathways of lipogenesis and glyceroneogenesis in this tissue. We found that rabbit adipose tissue has a low capacity for denovo fatty acid synthesis from glucose but a high capacity for synthesis from pyruvate and acetate.
openaire   +3 more sources

Combined effects of light and salinity on the growth performance in juveniles of the Malabar grouper, Epinephelus malabaricus

open access: yesFrontiers in Marine Science
IntroductionEnvironmental factors, including light and salinity, influence fish growth. It has been hypothesized that optimizing environmental factors can activate the endocrine system and enhance the growth performance of fish.
Yafan Zhu   +5 more
doaj   +1 more source

Evidence against the peroxisome proliferator-activated receptor α (PPARα) as the mediator for polyunsaturated fatty acid suppression of hepatic L-pyruvate kinase gene transcription

open access: yesJournal of Lipid Research, 2000
The glycolytic enzyme, L-pyruvate kinase (L-PK), plays an important role in hepatic glucose metabolism. Insulin and glucose induce L-PK gene expression, while glucagon and polyunsaturated fatty acids (PUFA) inhibit L-PK gene expression.
David A. Pan   +5 more
doaj   +1 more source

FAM120A couples SREBP-dependent transcription and splicing of lipogenesis enzymes downstream of mTORC1 [PDF]

open access: gold, 2023
Sungyun Cho   +16 more
openalex   +1 more source

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