Results 141 to 150 of about 75,579 (341)

Unlocking the Link of Twin Profiles of Plasma Fatty Acids and Genetic Risk and Their Interactions With Incident Dementia

Food Frontiers, EarlyView.
Plasma MUFAs, n‐6 PUFAs (particularly LA), and n‐3 PUFAs (particularly non‐DHA n‐3 PUFAs) were found to be inversely associated with dementia risk. The interactions with APOE genotypes and genetic risk score were also observed, as well as the mediation of serum biomarkers. The study highlights the importance of refining plasma fatty acid profiles based
Hao Ye, Haoyin Liu, Yin Li, Yingyu Huang, Jianxin Yao, Yang Ao, Xiaohui Liu, Xunan Lin, Xiaoran Song, Pan Zhuang, Yu Zhang, Jingjing Jiao   +11 more
wiley   +1 more source

Synergistic Regulation of Mammary Gland Ferroptosis by Vitamin E and Selenium Under Environmental Heat Stress

Food Frontiers, EarlyView.
Sodium selenite or vitamin E supplementation enhances antioxidant defenses in mouse mammary glands, reducing oxidative stress, lipid peroxidation, and iron accumulation. This boosts GPX4 activity, inhibits PTGS2, and activates mTORC1, improving milk fat droplet formation and protein synthesis, with the combined treatment showing the greatest benefit ...
Qianzi Zhang, Xiaoli Zhang, Haobin Li, Jinbiao Lai, Dongpang Chen, Siyu Yuan, Wutai Guan, Shihai Zhang   +7 more
wiley   +1 more source

Modulation of Lipogenesis and Glucose Consumption in HepG2 Cells and C2C12 Myotubes by Sophoricoside [PDF]

, 2013
Chongming Wu, Hong Luan, Shuai Wang, Xue Zhang, Ran Wang, Lifeng Jin, Peng Guo, Xi Chen   +7 more
openalex   +1 more source

The metabolic underpinnings of sebaceous lipogenesis

Communications Biology
Abstract Sebaceous glands synthesize and secrete sebum, a mélange of lipids and other cellular products that safeguards the mammalian integument. Differentiating sebocytes delaminate from the basal membrane and dislodge towards the gland’s middle, where they eventually undergo a poorly understood death mode in which the whole cell becomes a ...
Maria Schmidt, Hans Binder, Marlon R. Schneider   +2 more
openaire   +3 more sources

Ganoderic Acid A Alleviates High‐Fat Diet‐Induced Lipid Metabolism Disorders in Mice by Inhibiting Intestinal Farnesoid X Receptor

Food Frontiers, EarlyView.
Ganoderic acid A (GA) improved lipid metabolism disorders by inhibiting intestinal FXR. GA markedly suppressed the ileal intestinal FXR activity. Then, GA changed bile acid composition and upregulated hepatic Cyp7a1 mRNA through decreasing FXR target genes encoded protein levels.
Feng Lu, Shanshan Ju, Yi Ying, Jihan Liu, Chengfeng Yang, Min Li, Hong Zhou, Baoxue Yang   +7 more
wiley   +1 more source

Glycogen Synthase Kinase 3 Inactivation Induces Cell Senescence through Sterol Regulatory Element Binding Protein 1-Mediated Lipogenesis in Chang Cells [PDF]

, 2013
You‐Mie Kim, Insun Song, Yonghak Seo, Gyesoon Yoon   +3 more
openalex   +1 more source

Sulfated Polysaccharides in the Hallmarks of Metabolic Syndrome: Functions and Mechanisms

Food Frontiers, EarlyView.
The SPs sources are very diverse, including various fishes, sea cucumbers, seaweeds, etc. These SPs are able to improve the glucose and lipid metabolism disorders, hormonal dysregulation, oxidative stress, inflammatory response, complications, and gut homeostasis of MetS by regulating biochemical indicators related to MetS. ABSTRACT Metabolic syndrome (
Fuqiang Zhao, Chuan Li, Xin Zhang, Kexue Zhu, Chao Zhao, Deming Gong, Lulu Zhu, Yongcheng Li, Jun Cao, Shaoping Nie   +9 more
wiley   +1 more source

Review for "Inhibition of fatty acid synthase with <scp>FT</scp> ‐4101 safely reduces hepatic de novo lipogenesis and steatosis in obese subjects with <scp>NAFLD</scp> non‐alcoholic fatty liver disease: results from two early phase randomized trials"

, 2020
Adrian T. Billeter
openalex   +1 more source

Medicine‐Food Plant Polysaccharides Modulate Diabetes and Diabetic Complications Through Maintaining Gut Function: A Review

Food Frontiers, EarlyView.
Polysaccharides derived from medicine‐food plants restore intestinal barrier integrity and microbiota balance while modulating short‐chain fatty acid levels. These modifications significantly alleviate diabetes and its complications, including nephropathy, retinopathy, cardiovascular disease, and neuropathy.
Yi Long, Wanglong Yu, Pingping Yang, Minxuan Xu, Jitao Ling, Yuting Wu, Xiao Liu, Liu Ouyang, Yan Xiong, Jianping Liu, Yiming Gan, Jing Zhang, Peng Yu, Deju Zhang   +13 more
wiley   +1 more source

New Insights Into Ginseng and Clove Supplementation: Alleviating Obesity by Reducing Leptin Resistance and Reshaping the Gut Microbiota

Food Frontiers, EarlyView.
AEGC conferred substantial resistance to weight gain and reduced food intake. AEGC may alleviate LR by regulating the levels of LEP and ADP. AEGC elevated the diversity of gut microbiota and reconstructed the composition. Changes such as CAG‐873 in gut microbiota may be the reason why AEGC alleviates LR.
Weifeng Ni, Shen Yao, Shichao Li, Shichao Liu, Liwei Sun, Daqing Zhao, Zhengqi Dong, Siming Wang, Weinan Wang, Meichen Liu   +9 more
wiley   +1 more source