Results 161 to 170 of about 75,579 (341)

Multiomics analyses reveal that PRMT5 regulates membrane transport and cholesterol synthesis in white adipocytes

iMetaOmics, EarlyView.
Prmt5AKO downregulates genes related to fatty acid transport and triacylglycerol synthesis, while upregulating genes involved in glucose transport and cholesterol biogenesis. These changes cause alternation in lipid composition and metabolic phenotypes of Prmt5AKO mice. Abstract The adipose tissue (AT) is a main regulator of systemic energy homeostasis,
Xiyue Chen, Zhihao Jia, Xiashiyao Zhang, Feng Yue, James F. Markworth, Christina R. Ferreira, Jun Wan, Shihuan Kuang   +7 more
wiley   +1 more source

Oxidative phosphorylation at the crossroads of cancer: Metabolic orchestration, stromal collusion, and emerging therapeutic horizons

Interdisciplinary Medicine, EarlyView.
Although most cancer cells rely on aerobic glycolysis, Oxidative phosphorylation (OXPHOS) remains essential for their survival, proliferation, and metastasis. With the emergence of OXPHOS‐targeted drugs, its therapeutic potential is becoming increasingly evident.
Keke Chen, Bo Wang, Hongying Shu, Jianxin Lyu, Wei Cui, Hezhi Fang   +5 more
wiley   +1 more source

Comparative Approach of the de novo Fatty Acid Synthesis (Lipogenesis) between Ruminant and Non Ruminant Mammalian Species: From Biochemical Level to the Main Regulatory Lipogenic Genes

, 2010
George P. Laliotis, Iosif Bizelis, E. Rogdakis   +2 more
openalex   +2 more sources

Role of hepatoma‐derived growth factor in promoting de novo lipogenesis and tumorigenesis in hepatocellular carcinoma [PDF]

, 2018
Xuejie Min, Jun Wen, Li Zhao, Kaiying Wang, Qingli Li, Gang Huang, Jianjun Liu, Xiaoping Zhao   +7 more
openalex   +1 more source

Developmental Patterns of Hepatic Peroxisome Proliferator‐Activated Receptor (PPAR) Expression in Xenopus laevis and Response to Pharmaceutical Agonists During Metamorphic Climax

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Peroxisome proliferator‐activated receptors (PPAR) are master transcriptional regulators that maintain metabolic homeostasis in vertebrates. Amphibians are often exposed to endocrine disrupting compounds (EDCs) that could dysregulate lipid metabolism.
Anna Bushong, Tyler D. Hoskins, Meredith Scherer, Maria S. Sepúlveda   +3 more
wiley   +1 more source

Persimmon carotenoid extract rich in β‐cryptoxanthin improves glucose homeostasis and reduces liver damage in high‐fat‐diet‐induced type 2 diabetic and metabolic dysfunction‐associated steatotic liver disease mice

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Background Persimmon (Diospyros kaki Thunb.) byproducts are a remarkable source of bioactive compounds, particularly carotenoids. Several studies suggest that carotenoids have beneficial effects in prevention of a large number of diseases. This study aims to highlight the effects of a persimmon carotenoid extract (PSCE) rich in β‐cryptoxanthin
Bryan Moreno‐Chamba, Nuria Martí, Antonio Cárdenas, María Soledad Fernández‐Pachón, Blanca Escudero‐López, Franz Martín, Julio Salazar‐Bermeo, Manuel Valero, Domingo Saura, María Concepción Martínez‐Madrid, Genoveva Berná   +10 more
wiley   +1 more source

‘Why do tumour cells glycolyse?’: From glycolysis through citrate to lipogenesis

, 2005
Leslie C. Costello, Renty Franklin
openalex   +2 more sources

GNPAT/USP30 Stabilizes DRP1 Protein to Promote Mitochondrial Fission and Functional Damage in COPD Progression

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Our previous study revealed the role of glycerol phosphate O‐acyltransferase (GNPAT) in regulating chronic obstructive pulmonary disease (COPD). However, its further mechanisms remained unclear. In this study, COPD models were established by exposing mice to cigarette smoke particulates.
Xin‐Gui Cheng, Yun‐Chan Liu, Fei Chen, Ji‐Wei Li, Xiao‐Zhou Yao, Qing‐Yun Chen   +5 more
wiley   +1 more source

LIPOGENESIS FROM GLUCOSE IN THE NORMAL AND LIVERLESS ANIMAL AS STUDIED WITH C14-LABELED GLUCOSE

, 1949
E. J. Masoro, I.L. Chaikoff, William G. Dauben   +2 more
openalex   +1 more source

Role of Dietary Fructose and Hepatic De Novo Lipogenesis in Fatty Liver Disease

Digestive Diseases and Sciences, 2016
S. Softic, S. Softic, David E. Cohen, C. Kahn   +3 more
semanticscholar   +1 more source