Results 41 to 50 of about 498 (114)

Pipeline of Known Chemical Classes of Antibiotics

open access: yesAntibiotics, 2013
Many approaches are used to discover new antibiotic compounds, one of the most widespread being the chemical modification of known antibiotics. This type of discovery has been so important in the development of new antibiotics that most antibiotics used ...
Cristina d'Urso de Souza Mendes   +1 more
doaj   +1 more source

REVIEW ON CLINICALLY DEVELOPING ANTIBIOTICS [PDF]

open access: yes, 2018
The world is running out of antibiotics. Between 1940 and 1962, more than 20 new classes of antibiotics were marketed. Since then, only two new classes of antibiotics were marketed.
M., Sudha   +3 more
core   +3 more sources

Recommendations of the Spanish Antibiogram Committee (COESANT) for selecting antimicrobial agents and concentrations for in vitro susceptibility studies using automated systems [PDF]

open access: yes, 2020
Automated antimicrobial susceptibility testing devices are widely implemented in clinical microbiology laboratories in Spain, mainly using EUCAST (European Committee on Antimicrobial Susceptibility Testing) breakpoints.
Alós, Juan Ignacio   +29 more
core   +1 more source

Kimyrsa and Orbactiv – A Tale of Two Formulations

open access: yesDrug Design, Development and Therapy, 2023
Brittany T Jackson,1 David B Cluck,2 Andrés F Henao-Martínez,3 Daniel B Chastain4 1Department of Pharmacy, Mount Sinai Morningside, New York, NY, 10025, USA; 2Department of Pharmacy Practice, Bill Gatton College of Pharmacy East Tennessee State ...
Jackson BT   +3 more
doaj  

A retrospective multicentre study on dalbavancin effectiveness and cost-evaluation in sternotomic wound infection treatment: DALBA SWIT Study [PDF]

open access: yes, 2022
To evaluate the cost-effectiveness of dalbavancin compared with standard of care (SoC) treatment as daptomycin or teicoplanin in patients with sternal wound infections (SWI)
Albertini, Alberto   +12 more
core   +2 more sources

Antibiotic Resistance: A Genetic and Physiological Perspective

open access: yesMedComm, Volume 6, Issue 11, November 2025.
The development of resistance to antimicrobials and their historical progression are depicted in this graphic. It draws attention to important biochemical, physiological, and genetic factors that contribute to AMR, such as the transmission of genes, the development of biofilms, and the inactivation of antibiotics.
Rania G. Elbaiomy   +9 more
wiley   +1 more source

Long-Acting Antibiotics: New Opportunities Beyond Acute Bacterial Skin and Skin Structure Infections (ABSSSIs)!

open access: yesAntibiotics
Currently, two long-acting antibiotics are available: oritavancin (ORI) and dalbavancin (DBV) [...]
Emanuele Pontali   +3 more
doaj   +1 more source

Telavancin — New Antimicrobial Active Against Multiresistant Gram-Positive Pathogens. Clinical and Microbiological Features in Questions and Answers [PDF]

open access: yesКлиническая микробиология и антимикробная химиотерапия, 2015
Telavancin is a first marketed representative of semisinthetic lipoglycopeptides — new generation of glycopeptide antimicrobials. Telavancin is registered for the treatment of nosocomial pneumonia and skin and soft tissue infections caused by Gram ...
Dekhnich A.V.   +5 more
doaj  

Development of an LC–MS/MS Method for Quantifying Occidiofungin in Rabbit Plasma

open access: yesJournal of Mass Spectrometry, Volume 60, Issue 4, April 2025.
ABSTRACT Fungal infections are caused by opportunistic pathogens that can be life threatening and have been growing in prevalence. Many clinically relevant pathogens have resistance to or are developing resistance to the commonly used antifungal treatments.
Andrew Cothrell   +2 more
wiley   +1 more source

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