Systematic review and meta-analysis of the significance of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates [PDF]
The prevalence of heteroresistant vancomycin-intermediate Staphylococcus aureus (hVISA) is 1.3% in published studies. Clinical associations include high-inoculum infections and glycopeptide failure, with hVISA infections associated with a 2.37-times ...
Van Hal, S.J., Paterson, D.L.
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Expert Opinion on Dose Regimen and Therapeutic Drug Monitoring for Long-Term Use of Dalbavancin: Expert Review Panel [PDF]
Background: Dalbavancin is a lipoglycopeptide with a long elimination half-life, currently licensed for the treatment of acute bacterial skin and skin structure infections (ABSSSI) in adults.
Cuervo, Guillermo +10 more
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New therapeutic alternatives to treat Acute Bacterial Skin and Skin Structure Infections ...
Mody, VV, Singh, A
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Multidrug-resistant Staphylococcus epidermidis (MDRSE) is responsible for difficult-to-treat infections in humans and hospital-acquired-infections. This review discusses the epidemiology, microbiology, diagnosis, and treatment of MDRSE infection and ...
Valentina Siciliano +4 more
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NEUROPSYCHIATRIC ADVERSE EFFECTS OF ANTIBACTERIAL AGENTS [PDF]
Anti-bacterial are agents that inhibit bacterial growth or kills bacteria and are a sub-type of antimicrobials. These are drugs used to treat infections, but they sometimes pose a threat of adverse events.
CYRIAC, SANTA TREASA, IYPE, DIVYA SARA
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Exploiting gene regulation as an approach to identify, analyze and utilize the biosynthetic pathways of the glycopeptide ristomycin A and the zincophore [S,S]-EDDS in Amycolatopsis japonicum [PDF]
The microbial secondary metabolism is a rich source for valuable products that have found their way into various clinical and industrial applications. A particularly productive bacterial genus for the discovery of natural products is Amycolatopsis.
Spohn, Marius
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Clinically Approved Antibiotics from 2010 to 2022 [PDF]
This review discusses small molecule antibiotics approved for clinical use in the time frame 2010-2022. This time span saw the approval of four synthetic antibiotics (bedaquiline, pretomanid, delafloxacin, tedizolid), nine natural product derivatives ...
Gademann, Karl, Jung, Erik
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Financial Analysis of Dalbavancin for Acute Bacterial Skin and Skin Structure Infections for Self-Pay Patients [PDF]
© 2020, The Author(s). Introduction: Acute bacterial skin and skin structure infections (ABSSSI) are an increasing cause of admission in the self-pay population.
Bland, Christopher M. +5 more
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New antimicrobials and new therapy strategies for endocarditis. Weapons that should be defended [PDF]
The overall low-quality evidence concerning the clinical benefits of different antibiotic regimens for the treatment of infective endocarditis (IE), which has made it difficult to strongly support or reject any regimen of antibiotic therapy, has led to a
Cancelli, Francesca +6 more
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Partial outpatient oral antibiotic treatment of infective endocarditis is non-inferior to inpatient intravenous antibiotic therapy [PDF]
A clinical decision report using: Iversen K, Ihlemann N, Gill SU, et al. Partial Oral versus Intravenous Antibiotic Treatment of Endocarditis. N Engl J Med. 2019; 380:415-424.
Murphy, Nicholas J
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