Results 11 to 20 of about 498 (114)

Heartbreaking Decisions: The Dogma and Uncertainties of Antimicrobial Therapy in Infective Endocarditis

open access: yesPathogens, 2023
Infective endocarditis (IE) is a rare but increasingly prevalent disease with high morbidity and mortality, requiring antimicrobials and at times surgical intervention. Through the decades of healthcare professionals’ experience with managing IE, certain
Jennifer L. Adema   +5 more
doaj   +1 more source

Glycopeptide Hypersensitivity and Adverse Reactions

open access: yesPharmacy, 2020
Glycopeptides, such as vancomycin and teicoplanin, are primarily used in the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections, such as cellulitis, endocarditis, meningitis, pneumonia, and septicemia, and are some of the most ...
Vanthida Huang   +2 more
doaj   +1 more source

Antibiotics and Carbohydrate-Containing Drugs Targeting Bacterial Cell Envelopes: An Overview

open access: yesPharmaceuticals, 2022
Certain bacteria constitute a threat to humans due to their ability to escape host defenses as they easily develop drug resistance. Bacteria are classified into gram-positive and gram-negative according to the composition of the cell membrane structure ...
Federico Riu   +7 more
doaj   +1 more source

Determination of a Tentative Epidemiological Cut-Off Value (ECOFF) for Dalbavancin and Enterococcus faecium [PDF]

open access: yes, 2021
Dalbavancin is a lipoglycopeptide antibiotic that shows potent activity against Gram-positive bacteria. It circumvents vanB-type glycopeptide resistance mechanisms; however, data on the in vitro activity of dalbavancin for Enterococcus faecium (E ...
Fleige, Carola   +5 more
core   +1 more source

Adaptive Laboratory Evolution of Staphylococcus aureus Resistance to Vancomycin and Daptomycin: Mutation Patterns and Cross-Resistance

open access: yesAntibiotics, 2023
Vancomycin and daptomycin are first-line drugs for the treatment of complicated methicillin-resistant Staphylococcus aureus (MRSA) infections, including bacteremia.
Vladimir Gostev   +9 more
doaj   +1 more source

Orthopaedic Implant-Associated Staphylococcal Infections: A Critical Reappraisal of Unmet Clinical Needs Associated with the Implementation of the Best Antibiotic Choice

open access: yesAntibiotics, 2022
Infections associated with orthopaedic implants represent a major health concern characterized by a remarkable incidence of morbidity and mortality. The wide variety of clinical scenarios encountered in the heterogeneous world of infections associated ...
Milo Gatti   +9 more
doaj   +1 more source

Two Novel Semisynthetic Lipoglycopeptides Active against Staphylococcus aureus Biofilms and Cells in Late Stationary Growth Phase

open access: yesPharmaceuticals, 2021
The increase in antibiotic resistance among Gram-positive bacteria underscores the urgent need to develop new antibiotics. New antibiotics should target actively growing susceptible bacteria that are resistant to clinically accepted antibiotics including
Vladimir Vimberg   +6 more
doaj   +1 more source

Novel antimicrobial strategies to treat multi‐drug resistant Staphylococcus aureus infections

open access: yesMicrobial Biotechnology, Volume 16, Issue 7, Page 1456-1474, July 2023., 2023
Summary of novel strategies currently being developed to treat multi‐drug resistant Staphylococcus aureus infections. Abstract Antimicrobial resistance is a major obstacle for the treatment of infectious diseases and currently represents one of the most significant threats to global health. Staphylococcus aureus remains a formidable human pathogen with
Edward J. A. Douglas   +3 more
wiley   +1 more source

Nanoparticle‐Based Formulations of Glycopeptide Antibiotics: A Means for Overcoming Vancomycin Resistance in Bacterial Pathogens?

open access: yesAdvanced NanoBiomed Research, Volume 3, Issue 4, April 2023., 2023
The rapid worldwide spreading of antimicrobial resistance (AMR) in bacterial pathogens represents an epic threat to human health and new strategies for overcoming AMR are urgently needed. Herein, different nanoparticle‐based formulations of the cell‐wall‐targeting glycopeptide antibiotics vancomycin and teicoplanin are reviewed and their potential of ...
Bhanu Kiran Pothineni, Adrian Keller
wiley   +1 more source

Developmental Pharmacokinetics of Antibiotics Used in Neonatal ICU: Focus on Preterm Infants

open access: yesBiomedicines, 2023
Neonatal Infections are among the most common reasons for admission to the intensive care unit. Neonatal sepsis (NS) significantly contributes to mortality rates.
Olga I. Butranova   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy