Results 11 to 20 of about 498 (114)
Infective endocarditis (IE) is a rare but increasingly prevalent disease with high morbidity and mortality, requiring antimicrobials and at times surgical intervention. Through the decades of healthcare professionals’ experience with managing IE, certain
Jennifer L. Adema +5 more
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Glycopeptide Hypersensitivity and Adverse Reactions
Glycopeptides, such as vancomycin and teicoplanin, are primarily used in the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections, such as cellulitis, endocarditis, meningitis, pneumonia, and septicemia, and are some of the most ...
Vanthida Huang +2 more
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Antibiotics and Carbohydrate-Containing Drugs Targeting Bacterial Cell Envelopes: An Overview
Certain bacteria constitute a threat to humans due to their ability to escape host defenses as they easily develop drug resistance. Bacteria are classified into gram-positive and gram-negative according to the composition of the cell membrane structure ...
Federico Riu +7 more
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Determination of a Tentative Epidemiological Cut-Off Value (ECOFF) for Dalbavancin and Enterococcus faecium [PDF]
Dalbavancin is a lipoglycopeptide antibiotic that shows potent activity against Gram-positive bacteria. It circumvents vanB-type glycopeptide resistance mechanisms; however, data on the in vitro activity of dalbavancin for Enterococcus faecium (E ...
Fleige, Carola +5 more
core +1 more source
Vancomycin and daptomycin are first-line drugs for the treatment of complicated methicillin-resistant Staphylococcus aureus (MRSA) infections, including bacteremia.
Vladimir Gostev +9 more
doaj +1 more source
Infections associated with orthopaedic implants represent a major health concern characterized by a remarkable incidence of morbidity and mortality. The wide variety of clinical scenarios encountered in the heterogeneous world of infections associated ...
Milo Gatti +9 more
doaj +1 more source
The increase in antibiotic resistance among Gram-positive bacteria underscores the urgent need to develop new antibiotics. New antibiotics should target actively growing susceptible bacteria that are resistant to clinically accepted antibiotics including
Vladimir Vimberg +6 more
doaj +1 more source
Novel antimicrobial strategies to treat multi‐drug resistant Staphylococcus aureus infections
Summary of novel strategies currently being developed to treat multi‐drug resistant Staphylococcus aureus infections. Abstract Antimicrobial resistance is a major obstacle for the treatment of infectious diseases and currently represents one of the most significant threats to global health. Staphylococcus aureus remains a formidable human pathogen with
Edward J. A. Douglas +3 more
wiley +1 more source
The rapid worldwide spreading of antimicrobial resistance (AMR) in bacterial pathogens represents an epic threat to human health and new strategies for overcoming AMR are urgently needed. Herein, different nanoparticle‐based formulations of the cell‐wall‐targeting glycopeptide antibiotics vancomycin and teicoplanin are reviewed and their potential of ...
Bhanu Kiran Pothineni, Adrian Keller
wiley +1 more source
Developmental Pharmacokinetics of Antibiotics Used in Neonatal ICU: Focus on Preterm Infants
Neonatal Infections are among the most common reasons for admission to the intensive care unit. Neonatal sepsis (NS) significantly contributes to mortality rates.
Olga I. Butranova +3 more
doaj +1 more source

