Results 81 to 90 of about 89,481 (251)

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

Insights into the biopharmaceutical behavior of oral lipid-based formulations using advanced analytical techniques and mathematical modeling [PDF]

, 2014
Lipid-based formulations (LBFs) are effective means for the oral delivery of poorly water-soluble compounds. The drug is already solubilized in the formulation and, thus, the critical dissolution step is circumvented. However, the oral bioavailability is
Stillhart, Cordula Edith
core   +1 more source

Lipid droplet profiling during neutrophil differentiation by stimulated Raman scattering microscopy

Biotechnology Progress, EarlyView.
Abstract Lipid droplets (LDs) are dynamic organelles that serve as metabolic hubs and emerging regulators of immune cell fate. Although LDs have been implicated in immune regulation, how LD metabolism is remodeled during neutrophil differentiation and how stage‐specific LD dynamics shape mature neutrophil function remain poorly defined.
Ting‐Jung Sung, Bin Dong, Jingqiao Shen, Yan Tan, Chi Zhang, Xiaoping Bao   +5 more
wiley   +1 more source

Species-specific characteristics of variables associated with milk lipolysis induced by a feed restriction in cows, ewes, and goats

Journal of Dairy Science
: Milk lipolysis in ruminant species is a major issue because it affects milk quality and its ability to be processed. Previous studies have shown that comparable levels of dietary restriction significantly increase milk lipolysis in dairy cows, whereas ...
Laurence Bernard, Andrea Rau, Catherine Hurtaud, Hélène Larroque, Muriel Bonnet, Christelle Cebo, Mylène Delosière   +6 more
doaj   +1 more source

Short‐Term Effects of Golden Rice Cookies Enriched With Piper crocatum Extract on Lipid Profiles in Adults With Diabetes: A Quasi‐Experimental Study

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Background Diabetes mellitus (DM) commonly coexists with dyslipidemia and elevated cardiovascular risk. Food‐based interventions containing antioxidants and polyphenols may support lipid metabolism. This study evaluated the short‐term effects of Golden Rice cookies enriched with active Piper crocatum extract on lipid profiles in adults with DM.
Altje Suwardi Abram, Andina Setyawati, Andi Masyitha Irwan   +2 more
wiley   +1 more source

Phenolic‐Associated Dietary Fiber Ingredients From Agro‐Industrial Residues: Processing‐Dependent Identity and Food‐Grade Translation

ChemFoodChem, EarlyView.
Agro‐industrial residues contain dietary fiber and phenolics, but coexistence alone does not establish a phenolic‐bound ingredient. Processing‐dependent identity is verified through fraction‐specific analysis and common‐basis mass balance. Food‐grade translation requires final‐product performance, sensory acceptance, safety, and claim‐matched ...
Yitong Niu, Ireland LaBass, Sicheng Wang, Cheu Peng Leh, Ting Han   +4 more
wiley   +1 more source

Membrane lipid metabolism as a regulatory frontier in neural crest biology: Roles for sphingolipids, cholesterol, and lipid rafts

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are multipotent, migratory stem‐like cells essential for vertebrate development that contribute broadly to many tissues including the craniofacial skeleton, peripheral nervous system, and pigment‐producing cells. Their development progresses through phases of induction, specification, delamination, migration, and ...
Allison E. Mancini, Mallorie P. Jenne, Michael L. Piacentino   +2 more
wiley   +1 more source

Age-associated accumulation of B cells promotes macrophage inflammation and inhibits lipolysis in adipose tissue during sepsis

Cell Reports
Summary: Non-canonical lipolysis induced by inflammatory cytokines or Toll-like receptor ligands is required for the regulation of inflammation during endotoxemia and sepsis.
Anna Carey, Katie Nguyen, Pranathi Kandikonda, Victor Kruglov, Claire Bradley, Korbyn J.V. Dahlquist, Stephanie Cholensky, Whitney Swanson, Vladimir P. Badovinac, Thomas S. Griffith, Christina D. Camell   +10 more
doaj   +1 more source

Control of lipolysis in intra-abdominal fat cells of nonhuman primates: comparison with humans.

Journal of Lipid Research, 1995
The mechanisms that control lipolysis in intra-abdominal fat cells from various primate species, the marmoset (Callithrix jacchus), the baboon (Papio papio), and the macaque (Macaca fascicularis), were compared to those of human intraabdominal fat cells.
A Bousquet-Mélou, J Galitzky, M Lafontan, M Berlan   +3 more
doaj   +1 more source

Activin B inhibits lipolysis in 3T3-L1 adipocytes

, 2010
Activin B, consisting of two inhibin betaB (INHBB) subunits, is a hormone known to affect gonadal function, reproduction and fetal development. We have reported that INHBB and activin B receptors are highly expressed in adipocytes suggesting that activin
Svensson, Per-Arne,, Magnusson, Björn,, Sjöholm, Kajsa,, Carlsson, Lena M S,   +3 more
core   +1 more source