Results 11 to 20 of about 29,837 (216)

A Novel Cell-Penetrating Lipopeptide for DNA Binding, Self-Assembly, and Delivery Into HeLa and Pluripotent Stem Cells. [PDF]

open access: yesJ Pept Sci
A lipopeptide is designed that contains an epitope from simian virus T‐antigen (SV40T, PKKKRKV) conjugated to an N‐terminal palmitoyl (C16‐) moiety, which acts as a cell‐penetrating lipopeptide, with additional aggregation propensity conferred by the lipid chain. The lipopeptide enables DNA delivery into the cytoplasm and nucleus.
de Mello LR   +6 more
europepmc   +2 more sources

Lipopeptides for Vaccine Development [PDF]

open access: yesBioconjugate Chemistry, 2021
The development of lipopeptides (lipidated peptides) for vaccines is discussed, including their role as antigens and/or adjuvants. Distinct classes of lipopeptide architectures are covered including simple linear and ligated constructs and lipid core peptides.
openaire   +3 more sources

Bioinformatic prospecting and synthesis of a bifunctional lipopeptide antibiotic that evades resistance

open access: yesScience, 2022
Emerging resistance to currently used antibiotics is a global public health crisis. Because most of the biosynthetic capacity within the bacterial kingdom has remained silent in previous antibiotic discovery efforts, uncharacterized biosynthetic gene ...
Zongqiang Wang   +4 more
semanticscholar   +1 more source

Lipopeptides in cosmetics [PDF]

open access: yesInternational Journal of Cosmetic Science, 2010
SynopsisLipopeptides are biosurfactants extensively used in cosmetics. The consumption of cosmetics containing lipopeptides is increasing as a result of the exceptional surface properties and diverse biological activities of lipopeptides which facilitate a vast number of applications not only in the pharmaceutics industry which includes cosmetics but ...
M, Kanlayavattanakul, N, Lourith
openaire   +2 more sources

Polymyxin and lipopeptide antibiotics: membrane-targeting drugs of last resort

open access: yesMicrobiology, 2022
The polymyxin and lipopeptide classes of antibiotics are membrane-targeting drugs of last resort used to treat infections caused by multi-drug-resistant pathogens. Despite similar structures, these two antibiotic classes have distinct modes of action and
E. Ledger, A. Sabnis, A. Edwards
semanticscholar   +1 more source

Liposome encapsulated surfactant abetted copper nanoparticles alleviates biofilm mediated virulence in pathogenic Pseudomonas aeruginosa and MRSA

open access: yesScientific Reports, 2021
In the present study lipopeptide biosurfactant with high emulsification capacity produced by human skin bacterium Paenibacillus thiaminolyticus was purified and subjected to FTIR and NMR spectral analysis which gave evidence of the active characteristics
Suganya Kannan   +3 more
doaj   +1 more source

Study on the application potential of lipopeptide fermentation broth in oil recovery

open access: yesEnergy Science & Engineering, 2022
Microbial flooding is a new enhanced‐oil‐recovery technology for the petroleum industry. In this study, a strain of Bacillus subtilis named SL‐2 was isolated from oil‐well‐produced fluid. B. subtilis produces the lipopeptide surfactin.
Huidong Wang   +4 more
doaj   +1 more source

Charting the Lipopeptidome of Nonpathogenic Pseudomonas

open access: yesmSystems, 2023
A major source of pseudomonad-specialized metabolites is the nonribosomal peptide synthetases (NRPSs) assembling siderophores and lipopeptides. Cyclic lipopeptides (CLPs) of the Mycin and Peptin families are frequently associated with, but not restricted
Catherine Cesa-Luna   +7 more
doaj   +1 more source

Bacillus licheniformis: The unexplored alternative for the anaerobic production of lipopeptide biosurfactants?

open access: yesBiotechnology Advances, 2022
Microbial biosurfactants have attracted the attention of researchers and companies for the last decades, as they are considered promising candidates to replace chemical surfactants in numerous applications.
Eduardo J. Gudiña, J. Teixeira
semanticscholar   +1 more source

Antimicrobial Activity of Lipopeptide Biosurfactants Against Foodborne Pathogen and Food Spoilage Microorganisms and Their Cytotoxicity

open access: yesFrontiers in Microbiology, 2021
Lipopeptide biosurfactants produced by Bacillus sp. were assessed regarding their antimicrobial activity against foodborne pathogenic and food spoilage microorganisms.
Konstantina Kourmentza   +8 more
semanticscholar   +1 more source

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