Results 61 to 70 of about 26,449 (239)

Co-Culture of White Rot Fungi Pleurotus ostreatus P5 and Bacillus amyloliquefaciens B2: A Strategy to Enhance Lipopeptide Production and Suppress of Fusarium Wilt of Cucumber

open access: yesJournal of Fungi, 2023
Fusarium wilt, caused by Fusarium oxysporum f. sp. cucumerinum (FOC), poses a serious threat to cucumber productivity. Compared to traditional chemical pesticides, biological control strategies have attracted more attention recently owing to their ...
Man Xu   +5 more
doaj   +1 more source

Lipopeptide Pepducins as Therapeutic Agents

open access: yes, 2021
Pepducins are lipidated peptides that target the intracellular loops of G protein-coupled receptors (GPCRs) in order to modulate transmembrane signaling to internally located effectors. With a wide array of potential activities ranging from partial, biased, or full agonism to antagonism, pepducins represent a versatile class of compounds that can be ...
Michael, Emily   +2 more
openaire   +3 more sources

Mechanism of Isonitrilase, a Nonheme Iron Decarboxylase Involved in the Biosynthesis of the Isonitrile Group in Peptides: A Computational Study

open access: yesChemistry – A European Journal, EarlyView.
A combination of molecular dynamics and quantum mechanics calculations shows that substrate is tightly bound inside the enzyme structure that enables two successive catalytic cycles with dioxygen and α‐ketoglutarate with an initial desaturation followed by hydrogen abstraction and decarboxylation steps to form an isonitrile substituent.
Chengxu Zhu, Sam P. de Visser
wiley   +1 more source

Antagonistic mechanism of Bacillus velezensis HX0039 as a biocontrol agent against Trichoderma virens-induced “Sanghuang” green mold

open access: yesApplied and Environmental Microbiology
Green mold disease caused by Trichoderma spp. is one of the serious challenges in the production of “Sanghuang” mushroom (Sanghuangporus vaninii).
Ying Zhang   +8 more
doaj   +1 more source

Biosurfactant Production by Bacillus amyloliquefaciens C11 and Streptomyces lavendulae C27 Isolated from a Biopurification System for Environmental Applications

open access: yesMicroorganisms, 2022
Biosurfactant-producing bacteria can be found in contaminated environments such as biopurification systems (BPS) for pesticide treatments. A total of 18 isolates were screened to determine their ability to produce extracellular biosurfactants, using ...
M. Cristina Diez   +5 more
doaj   +1 more source

C‐Terminal Functionalization Methods of Amino Acids, Peptides, and Proteins

open access: yesChemistry – A European Journal, EarlyView.
C‐terminal functionalization offers powerful routes to peptide and protein diversification, yet epimerization, hydrolysis, and selectivity remain key challenges. This Review surveys enzymatic, decarboxylative, and condensation strategies, highlighting advances toward chemo‐ and regioselective, protecting‐group‐free, atom‐efficient methods applicable to
Jay Hanssens   +3 more
wiley   +1 more source

Preparation and Properties of Semi-Self-Assembled Lipopeptide Vesicles

open access: yes, 2019
Novel lipopeptide vesicles are prepared from self-assembled nanomembranes through an extrusion method. The size of vesicles can be controlled by the pore diameter of the extrusion filter.
Yuxia Luan (2465857)   +5 more
core   +1 more source

Enhancing the solubility of SARS-CoV-2 inhibitors to increase future prospects for clinical development

open access: yesJournal of Virology
SARS-CoV-2 poses an ongoing threat to human health as variants continue to emerge. Several effective vaccines are available, but a diminishing number of Americans receive the updated vaccines (only 22% received the 2023 update).
Ariel J. Kuhn   +12 more
doaj   +1 more source

Total Synthesis of Fellutamide B and Deoxy-Fellutamides B, C, and D

open access: yesMarine Drugs, 2013
The total syntheses of the marine-derived lipopeptide natural product fellutamide B and deoxy-fellutamides B, C, and D are reported. These compounds were accessed through a novel solid-phase synthetic strategy using Weinreb amide-derived resin.
Richard J. Payne   +4 more
doaj   +1 more source

Crosstalk Between Parkinson's Disease and Colorectal Cancer: Genetic Mechanisms, Gut Microbiota, and Therapeutic Insights

open access: yesHealth Care Science, EarlyView.
This review elucidates the crosstalk between Parkinson's disease and colorectal cancer, driven by shared genetics (PRKN, PINK1, DJ‐1) involving oxidative stress, cell cycle regulation, and inflammation. It identifies the gut microbiota—via functional amyloids and short‐chain fatty acids (SCFAs)—as a mechanistic bridge, offering insights for dual ...
Jiacheng Ying   +6 more
wiley   +1 more source

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