Results 81 to 90 of about 24,712 (234)

Mitochondria‐targeted nanomedicine for cancer therapy: Targeting strategies, therapeutic mechanisms, and translational challenges

open access: yesInterdisciplinary Medicine, EarlyView.
This review highlights recent advances in mitochondria‐targeted nanomedicine for cancer therapy. It summarizes key targeting strategies and delineates four principal therapeutic mechanisms: oxidative stress–induced mitochondrial dysfunction, disruption of energy metabolism, direct mitochondrial damage, and induction of immunogenic cell death.
Linfeng Xiao   +7 more
wiley   +1 more source

Anti‐inflammatory and cytotoxic properties of kānuka (Kunzea ericoides) subcritical water extract

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Kānuka (Kunzea ericoides) is a medicinal plant native to New Zealand with numerous therapeutic benefits due to its rich bioactive profile. Although several in vitro studies have shown promising anti‐inflammatory activity, substantial evidence elucidating its underlying inflammatory regulatory mechanism and evaluating its cytotoxic ...
Indhuja Devadass   +2 more
wiley   +1 more source

Acaricidal Activity of Biosurfactants Produced by Serratia ureilytica on Tetranychus urticae and Their Compatibility with the Predatory Mite Amblyseius swirskii

open access: yesMicrobiology Research
This study evaluated the acaricidal effects of biosurfactants produced by Serratia ureilytica against the two-spotted spider mite Tetranychus urticae and their compatibility with the predatory mite Ambliseus swirski.
Arnoldo Wong-Villareal   +10 more
doaj   +1 more source

Surfactant Enhanced Bioremediation of Saline Diesel Contaminated Water by a Novel Bacterial Halophilic Consortium

open access: yesJournal of Surfactants and Detergents, EarlyView.
ABSTRACT The use of microorganisms is an evolving method for the degradation of hydrocarbon contaminants. In this aim, halophilic hydrocarbon degrading bacteria were isolated from oil contaminated soil in Tunisia. A lipopeptide biosurfactant produced by Bacillus subtilis SPB1 was tested to increase diesel biodegradation along with co‐inoculation with ...
Inès Mnif, Dhouha Ghribi
wiley   +1 more source

Lipopeptides: from self-assembly to bioactivity [PDF]

open access: yesChemical Communications, 2015
This Feature Article discusses several classes of lipopeptide with important biomedical applications as antimicrobial and antifungal agents, in immune therapies and in personal care applications among others.
openaire   +4 more sources

Combined application of Bacillus velezensis JDB15 and Trichoderma harzianum JDL4 suppresses banana Fusarium wilt under controlled conditions

open access: yesPest Management Science, EarlyView.
The surfactin C secreted by JDB15 and the probable parasitism of JDL4 lead to the leakage of intracellular macromolecules and the degradation of hyphae, respectively. Combined application of the two strains effectively controls banana Fusarium wilt under controlled conditions.
Deng Chen   +13 more
wiley   +1 more source

Type I interferon overactivation in sera of patients with anti‐MDA5‐positive dermatomyositis‐associated interstitial lung disease

open access: yesRheumatology &Autoimmunity, EarlyView.
Sera from patients with anti‐MDA5‐positive dermatomyositis‐associated interstitial lung disease (ILD) exhibit significantly higher type I interferon (IFN‐I) bioactivity and interferon‐stimulated gene‐inducing activity compared to anti‐ARS‐positive ILD and healthy controls.
Shohei Nakamura   +3 more
wiley   +1 more source

Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide [PDF]

open access: yes, 2007
SummaryTLR2 in association with TLR1 or TLR6 plays an important role in the innate immune response by recognizing microbial lipoproteins and lipopeptides.
Jin, Mi Sun   +7 more
core   +1 more source

Peptide‐based antibacterial nanoplatforms: Design principles, stimuli‐regulated behaviors, and applications

open access: yesResponsive Materials, EarlyView.
Peptide‐based antibacterial nanoplatforms, encompassing self‐assembled peptides and peptide‐engineered inorganic, polymeric, and lipid nanocarriers, are systematically reviewed. The article highlights design principles and stimuli‐responsive regulation for improving peptide stability, delivery efficiency, and antibacterial performance.
Peng Tan   +8 more
wiley   +1 more source

Time-dependent dosing of Fe2+ for improved lipopeptide production by marine Bacillus megaterium [PDF]

open access: yes, 2012
Background: Lipopeptide production is strongly influenced by trace metals. The availability of free Fe2+ in the media throughout the process of fermentation was found to be very critical.
Dhanarajan, Gunaseelan   +4 more
core   +1 more source

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