Results 71 to 80 of about 24,712 (234)

Prospection for potential new non-ribosomal peptide gene clusters in Bacillus genus isolated from fermented foods and soil through genome mining

open access: yesFrontiers in Microbiology
Experimental studies, though often very costly, lead to the discovery of known antimicrobial products. Yet, pathogenic microorganisms are proving increasingly resistant to pre-existing antimicrobial molecules, and this is a cause for worldwide concern ...
Blaise Waongo   +5 more
doaj   +1 more source

Seven New and Two Known Lipopeptides as well as Five Known Polyketides: The Activated Production of Silent Metabolites in a Marine-Derived Fungus by Chemical Mutagenesis Strategy Using Diethyl Sulphate

open access: yesMarine Drugs, 2014
AD-2-1 is an antitumor fungal mutant obtained by diethyl sulfate mutagenesis of a marine-derived Penicillium purpurogenum G59. The G59 strain originally did not produce any metabolites with antitumor activities in MTT assays using K562 cells.
Chang-Jing Wu   +2 more
doaj   +1 more source

Co-Culture of White Rot Fungi Pleurotus ostreatus P5 and Bacillus amyloliquefaciens B2: A Strategy to Enhance Lipopeptide Production and Suppress of Fusarium Wilt of Cucumber

open access: yesJournal of Fungi, 2023
Fusarium wilt, caused by Fusarium oxysporum f. sp. cucumerinum (FOC), poses a serious threat to cucumber productivity. Compared to traditional chemical pesticides, biological control strategies have attracted more attention recently owing to their ...
Man Xu   +5 more
doaj   +1 more source

Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden

open access: yesChemFoodChem, EarlyView.
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley   +1 more source

Antagonistic mechanism of Bacillus velezensis HX0039 as a biocontrol agent against Trichoderma virens-induced “Sanghuang” green mold

open access: yesApplied and Environmental Microbiology
Green mold disease caused by Trichoderma spp. is one of the serious challenges in the production of “Sanghuang” mushroom (Sanghuangporus vaninii).
Ying Zhang   +8 more
doaj   +1 more source

Biosurfactant Production by Bacillus amyloliquefaciens C11 and Streptomyces lavendulae C27 Isolated from a Biopurification System for Environmental Applications

open access: yesMicroorganisms, 2022
Biosurfactant-producing bacteria can be found in contaminated environments such as biopurification systems (BPS) for pesticide treatments. A total of 18 isolates were screened to determine their ability to produce extracellular biosurfactants, using ...
M. Cristina Diez   +5 more
doaj   +1 more source

Lipopeptides: Biosynthesis and Applications [PDF]

open access: yesJournal of Microbial & Biochemical Technology, 2015
Microbial surfactants are amphiphilic molecules. They possess a strong tendency to reduce the interfacial tension among compounds. Biosurfactants possess diverse chemical structures and are nontoxic and hence are biodegradable. They have many applications in bioremediation, enhanced oil recovery, pharmaceutical and in food industry.
openaire   +1 more source

Crosstalk Between Parkinson's Disease and Colorectal Cancer: Genetic Mechanisms, Gut Microbiota, and Therapeutic Insights

open access: yesHealth Care Science, EarlyView.
This review elucidates the crosstalk between Parkinson's disease and colorectal cancer, driven by shared genetics (PRKN, PINK1, DJ‐1) involving oxidative stress, cell cycle regulation, and inflammation. It identifies the gut microbiota—via functional amyloids and short‐chain fatty acids (SCFAs)—as a mechanistic bridge, offering insights for dual ...
Jiacheng Ying   +6 more
wiley   +1 more source

Enhancing the solubility of SARS-CoV-2 inhibitors to increase future prospects for clinical development

open access: yesJournal of Virology
SARS-CoV-2 poses an ongoing threat to human health as variants continue to emerge. Several effective vaccines are available, but a diminishing number of Americans receive the updated vaccines (only 22% received the 2023 update).
Ariel J. Kuhn   +12 more
doaj   +1 more source

Total Synthesis of Fellutamide B and Deoxy-Fellutamides B, C, and D

open access: yesMarine Drugs, 2013
The total syntheses of the marine-derived lipopeptide natural product fellutamide B and deoxy-fellutamides B, C, and D are reported. These compounds were accessed through a novel solid-phase synthetic strategy using Weinreb amide-derived resin.
Richard J. Payne   +4 more
doaj   +1 more source

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