Results 21 to 30 of about 16,028 (215)
As TLR2 agonists, several lipopeptides had been proved to be candidate vaccine adjuvants. In our previous study, lipopeptides mimicking N-terminal structures of the bacterial lipoproteins were also able to promote antigen-specific immune response ...
Ling Mao +11 more
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Agricultural application studies, including field experiments and acute toxicity tests, were conducted for lipopeptides secreted by marine-derived Bacillus marinus B-9987.
Kang-bo GU +7 more
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Bacillus amyloliquefaciens (B. amyloliquefaciens) is widely used as beneficial bacteria for biological control, and the main antimicrobial substances are lipopeptides.
Xiaojiao LUO, Jing SUN, Yingjian LU
doaj +1 more source
Ultrashort antibacterial and antifungal lipopeptides [PDF]
Host-defense cationic antimicrobial peptides (≈12–50 aa long) play an essential protective role in the innate immune system of all organisms. Lipopeptides, however, are produced only in bacteria and fungi during cultivation, and they are composed of specific lipophilic moieties attached to anionic peptides (six to seven amino acids)
Arik, Makovitzki +2 more
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Antibiotic resistance has become one of the world’s most severe problems because of the overuse of antibiotics. Antibiotic-resistant bacteria are more difficult to kill and more expensive to treat. Researchers have been studied on antibiotic alternatives
Yulin Chen +6 more
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The highly conserved extracellular domain of the transmembrane protein M2 (M2e) of the influenza A virus is a promising target for the development of broad-spectrum vaccines. However, M2e is a poor immunogen by itself and must be linked to an appropriate
Anna A. Zykova +6 more
doaj +1 more source
Genotoxicity of cationic lipopeptide nanoparticles
The genotoxicity of cationic lipopeptide nanoparticles (cLPNPs) was evaluated in vivo and in vitro comet assay and the in vivo chromosome aberrations test. In vitro comet assay, human blood cells were exposed to cLPNPs at the concentration of 2.5, 5, 10, 20, 40 and 100 μg/mL.
Aliy K. Zhanataev +7 more
openaire +3 more sources
ANTIMICROBIAL ACTIVITY OF LIPOPEPTIDES [PDF]
Abstract The constantly growing number of multidrug-resistant bacterial strains prompts the search for alternative treatments. Synthetic peptides based on natural antimicrobial peptides, also known as antimicrobial lipopeptides, can become a promising group of “drugs” to fight multi-resistant bacteria.
Paulina Czechowicz, Joanna Nowicka
openaire +2 more sources
The peptide sequence of diacyl lipopeptides determines dendritic cell TLR2-mediated NK activation. [PDF]
Natural killer (NK) cells are lymphocyte effectors that are activated to control certain microbial infections and tumors. Many NK-activating and regulating receptors are involved in regulating NK cell function.
Masahiro Azuma +9 more
doaj +1 more source
Bacillus lipopeptides inhibit lipase activity and promote 3T3-L1 preadipocyte differentiation
Bacillus lipopeptides have been reported to display anti-obesity effects. In the present study, Lipopeptides from Bacillus velezensis FJAT-45028 that consisted of iturin, fengycin and surfactin were reported.
Meichun Chen +5 more
doaj +1 more source

