Results 21 to 30 of about 16,028 (215)

Novel Synthetic Lipopeptides as Potential Mucosal Adjuvants Enhanced SARS-CoV-2 rRBD-Induced Immune Response

open access: yesFrontiers in Immunology, 2022
As TLR2 agonists, several lipopeptides had been proved to be candidate vaccine adjuvants. In our previous study, lipopeptides mimicking N-terminal structures of the bacterial lipoproteins were also able to promote antigen-specific immune response ...
Ling Mao   +11 more
doaj   +1 more source

Safe antifungal lipopeptides derived from Bacillus marinus B-9987 against grey mold caused by Botrytis cinerea

open access: yesJournal of Integrative Agriculture, 2017
Agricultural application studies, including field experiments and acute toxicity tests, were conducted for lipopeptides secreted by marine-derived Bacillus marinus B-9987.
Kang-bo GU   +7 more
doaj   +1 more source

Research Progress in the Biosynthesis, Antimicrobial Mechanism, and Application of Lipopeptides in Bacillus amyloliquefaciens

open access: yesShipin gongye ke-ji, 2022
Bacillus amyloliquefaciens (B. amyloliquefaciens) is widely used as beneficial bacteria for biological control, and the main antimicrobial substances are lipopeptides.
Xiaojiao LUO, Jing SUN, Yingjian LU
doaj   +1 more source

Ultrashort antibacterial and antifungal lipopeptides [PDF]

open access: yesProceedings of the National Academy of Sciences, 2006
Host-defense cationic antimicrobial peptides (≈12–50 aa long) play an essential protective role in the innate immune system of all organisms. Lipopeptides, however, are produced only in bacteria and fungi during cultivation, and they are composed of specific lipophilic moieties attached to anionic peptides (six to seven amino acids)
Arik, Makovitzki   +2 more
openaire   +2 more sources

Characterization of Lipopeptide Biosurfactants Produced by Bacillus licheniformis MB01 from Marine Sediments

open access: yesFrontiers in Microbiology, 2017
Antibiotic resistance has become one of the world’s most severe problems because of the overuse of antibiotics. Antibiotic-resistant bacteria are more difficult to kill and more expensive to treat. Researchers have been studied on antibiotic alternatives
Yulin Chen   +6 more
doaj   +1 more source

Highly Immunogenic Nanoparticles Based on a Fusion Protein Comprising the M2e of Influenza A Virus and a Lipopeptide

open access: yesViruses, 2020
The highly conserved extracellular domain of the transmembrane protein M2 (M2e) of the influenza A virus is a promising target for the development of broad-spectrum vaccines. However, M2e is a poor immunogen by itself and must be linked to an appropriate
Anna A. Zykova   +6 more
doaj   +1 more source

Genotoxicity of cationic lipopeptide nanoparticles

open access: yesToxicology Letters, 2020
The genotoxicity of cationic lipopeptide nanoparticles (cLPNPs) was evaluated in vivo and in vitro comet assay and the in vivo chromosome aberrations test. In vitro comet assay, human blood cells were exposed to cLPNPs at the concentration of 2.5, 5, 10, 20, 40 and 100 μg/mL.
Aliy K. Zhanataev   +7 more
openaire   +3 more sources

ANTIMICROBIAL ACTIVITY OF LIPOPEPTIDES [PDF]

open access: yesPostępy Mikrobiologii - Advancements of Microbiology, 2018
Abstract The constantly growing number of multidrug-resistant bacterial strains prompts the search for alternative treatments. Synthetic peptides based on natural antimicrobial peptides, also known as antimicrobial lipopeptides, can become a promising group of “drugs” to fight multi-resistant bacteria.
Paulina Czechowicz, Joanna Nowicka
openaire   +2 more sources

The peptide sequence of diacyl lipopeptides determines dendritic cell TLR2-mediated NK activation. [PDF]

open access: yesPLoS ONE, 2010
Natural killer (NK) cells are lymphocyte effectors that are activated to control certain microbial infections and tumors. Many NK-activating and regulating receptors are involved in regulating NK cell function.
Masahiro Azuma   +9 more
doaj   +1 more source

Bacillus lipopeptides inhibit lipase activity and promote 3T3-L1 preadipocyte differentiation

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry
Bacillus lipopeptides have been reported to display anti-obesity effects. In the present study, Lipopeptides from Bacillus velezensis FJAT-45028 that consisted of iturin, fengycin and surfactin were reported.
Meichun Chen   +5 more
doaj   +1 more source

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