Results 131 to 140 of about 988,006 (285)

Bioactive ph-sensitive nanoemulsion in melanoma cell lines [PDF]

Melanoma is an aggressive form of skin cancer with elevated propensity to metastasize. One of the major critical issues in the treatment of oncological patients is represented by the development of toxicity and resistance to the available therapies ...
Forte, Jacopo, Puglisi, Rossella, Grazia Ammendolia, Maria, Del Favero, Elena, Mattia, Gianfranco, Rinaldi, Federica, Ricci, Caterina, Marianecci, Carlotta, Gioia Fabiano, Maria, Carafa, Maria   +9 more
core   +1 more source

Stabilization of PUFA‐Rich Mayonnaise Against Lipid Oxidation: A Review of the Last Three Decades of Research

Journal of the American Oil Chemists' Society, EarlyView.
ABSTRACT Mayonnaise, a widely consumed oil‐in‐water emulsion, is highly susceptible to lipid oxidation due to its high content of polyunsaturated fatty acids (PUFAs) and the presence of pro‐oxidant factors such as low pH and iron from egg yolk. Over the past three decades, extensive research has focused on understanding oxidation mechanisms, analytical
Sakhi Ghelichi, Betül Yesiltas, Charlotte Jacobsen   +2 more
wiley   +1 more source

LC-MS/MS-guided profiling and network pharmacology analysis of bioactive compounds from Costus speciosus targeting type 2 diabetes: Insights from molecular docking and dynamics

Intelligent Pharmacy
Background/objectives: Costus speciosus is a medicinal plant traditionally used in Southeast Asia for its metabolic and anti-inflammatory properties, yet the molecular mechanisms underlying its bioactivity remain underexplored.
Taufik Muhammad Fakih, Jajang Japar Sodik, Rifky Rahmadi Khaerulihsan, Ihsan Jaya Fathurohman, Livia Syafnir, La Ode Akbar Rasydy, Muchtaridi Muchtaridi   +6 more
doaj   +1 more source

The Action of Bioactive Compounds on Human Health or Disease

Bioactive compounds are being studied to better understand their effects on health and disease. These compounds are found in several foods, such as beverages (wine, cedar, and juices), vegetable oils, spices (curcuma, pepper, etc.), teas, and infusions ...

core   +1 more source

Distinguishing between Bioactive and Modeled Compound Conformations through Mining of Emerging Chemical Patterns

, 2016
To systematically compare bioactive and theoretically derived compound conformations, we have analyzed 18 different sets of active small molecules with experimentally determined binding conformations and modeled conformers using a pattern recognition ...
Jens Auer (2418070), Jürgen Bajorath (1632358)   +1 more
core   +1 more source

Spectroscopic and In Silico Determination of the Structural and Antioxidant Properties of Essential Oils From Lavandula Species Cultivated in the Silivri Region of Istanbul

Journal of the American Oil Chemists' Society, EarlyView.
ABSTRACT Plants are important sources of bioactive compounds that contribute to nutrition, health maintenance, and disease prevention. In this study, the chemical composition and antioxidant potential of essential oils obtained from Lavandula angustifolia “Sevtopolis” and Lavandula × intermedia cultivated in the Silivri region of Istanbul were ...
Bilge Bicak, Beray Kizilkaya, Serda Kecel Gunduz, Aliye Demet Demirag, Sabriye Percin Ozkorucuklu   +4 more
wiley   +1 more source

Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis

Animal Research and One Health, EarlyView.
Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang, Tianqi Jin, Zexin Chen, Ye Gong, Qimin Liu, Zifang Wu, Heran Cao, Yan Li, Yuyan Liu, Tianhao Yang, Zhihong Jiang, Wuzi Dong   +11 more
wiley   +1 more source

Bioactive Azoles with Three Heteroatoms [PDF]

, 2010
This issue is dedicated to scientists belonging to either or both the fields of heterocyclic and medicinal chemistry. Nowadays, pharmaceutical industries are more and more dedicating their research towards different use or applications of the same ...
PACE, A
core  

Extracellular Vesicles‐Based Biological Macromolecule Delivery Systems: Biogenesis, Characterization, and Emerging Clinical Applications

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale membrane‐bound structures that play a pivotal role in intercellular communication by transporting bioactive molecules, including proteins, lipids, nucleic acids, and organelles, between cells. Originating from the endosomal pathway, EVs reflect the physiological and pathological status of their parent
Emine İncilay Torunoğlu, Zeynep Betül Sarı, Muhammed Emin Sarı, Erdi Can Aytar   +3 more
wiley   +1 more source

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source