Results 221 to 230 of about 988,006 (285)

Carbon dots as a smart nanoplatform for the blood‐brain barrier penetration and ischemic stroke therapy

Responsive Materials, EarlyView.
This review presents the structure and transport routes of the blood‐brain barrier, summarizes the ischemic stroke pathophysiological cascade, and discusses the BBB‐crossing mechanisms and multitarget therapeutic effects of carbon dots, demonstrating their promising theranostic potential for ischemic stroke.
Yanhan Huang, Xuan Hou, Haiping Zhao, Qi Kong, Xiayan Wang, Xiaokun Geng, Zaicheng Sun   +6 more
wiley   +1 more source

Encapsulation Strategies for Natural Bioactives in Clean-Label Meat Preservation: A Review. [PDF]

Foods
Haskaraca G, Sıçramaz H.
europepmc   +1 more source

Natural antibacterial silk produced by feeding silkworms with human hair derived carbon dots

Responsive Materials, EarlyView.
Blue‐fluorescent and antibacterial carbon dots, prepared from Crinis Carbonisatus (a traditional Chinese medicine made by calcinating human hair), are fed to silkworms to produce multifunctional silk, which retains its inherent mechanical properties, exhibits blue fluorescence, possesses antibacterial activity, and promotes the wound healing of rats as
Zhao‐Fan Wu, Xiao‐Feng Shi, Xiao‐Xiao Luo, Xi‐Rong Zhang, Yuan‐Qing Mao, Huan‐Ming Xiong   +5 more
wiley   +1 more source

Advanced Sustainable Approaches for the Valorization of High-Value Bioactive Compounds from Agro-Industrial Waste: Challenges and Opportunities. [PDF]

Foods
Savic IM, Savic Gajic IM.
europepmc   +1 more source

Driving Drugs Deeper: Force‐Driven Microneedle Systems for Active Therapy and Their Road Towards Clinical Implementation

Small, EarlyView.
Force‐driven microneedles are presented as active therapeutic microdevices that overcome the diffusion limits of conventional patches. By integrating gas generation, magnetic actuation, cavitation, or iontophoresis, these systems drive payloads deeper into tissue, enabling faster, more controlled delivery and highlighting key design principles and ...
Majed Amini, Phoebe Li, Hamed Shahsavan, Mahla Poudineh   +3 more
wiley   +1 more source

German and Roman Chamomile: Species-Specific Phytochemical Profiles, Bioactive Potential, and Relevance for Functional Foods and Nutraceutical Development. [PDF]

Nutrients
Such S, Zaguła G, Puchalski C, Czernicka M.   +3 more
europepmc   +1 more source

Pyrene‐linked heterocyclic pyrazoles: Synthesis, antimicrobial screening, and in silico molecular insights

Smart Molecules, EarlyView.
A series of novel pyrene‐linked heterocyclic pyrazoles were synthesized and structurally characterized. The compounds were evaluated for antimicrobial activity against selected bacterial and fungal strains, showing promising inhibitory effects. Molecular docking studies provided insights into binding interactions and structure–activity relationships ...
Dinkal V. Kasundra, Paresh N. Patel
wiley   +1 more source

Structural characterization and bioaccessibility of nanoliposomal lutein from pumpkin extract. [PDF]

Sci Rep
Sheikhzadeh M, Hakimzadeh V, Salehi EA, Mohseni S.   +3 more
europepmc   +1 more source

Design, synthesis and activity evaluation of tetrahydroisoquinoline‐based programmed cell death ligand 1 inhibitors

Smart Molecules, EarlyView.
Based on a 3D‐quantitative structure‐activity relationship pharmacophore model, structural optimization of Y6 yielded Y7f. Mechanistic studies revealed that Y7f acted as a programmed death receptor 1/programmed cell death ligand 1 (PD‐L1) interaction inhibitor by inducing PD‐L1 dimerization. Y7f restored T‐cell function.
Menglin Yu, Sen Cai, Yanyan Pan, Heshuang Wang, Fengwu Zhang, Aiyu Ma, Shixuan Lv, Xiuhan Guo, Shisheng Wang, Qiling Song, Chunyan Ma, Shuai Wang, Li Zhang, Jian Wang, Qingwei Meng, Yueqing Li   +15 more
wiley   +1 more source

Impact of Boiling on Cyanogenic Detoxification and Nutrient Retention in <i>Cnidoscolus aconitifolius</i> (Chaya) Leaves. [PDF]

Foods
Praditukrit C, Muangnoi C, Panritdum P, Sirivarasai J.   +3 more
europepmc   +1 more source