Results 161 to 170 of about 84,571 (285)

Bioactive flavonoids from Anacardium occidentale as promising natural inhibitors of Cryptococcus neoformans: a computational perspective on secondary metabolites against critical fungal pathogens. [PDF]

Arch Microbiol
da Silva MVF, Silva J, de Oliveira VM, da Rocha MN, de Morais SM, Marinho ES.   +5 more
europepmc   +1 more source

Enhanced Rheological and Filtration Performance of Drilling Fluids Using Fe3O4/Saponin/Cu(II) Nanocomposites: Synthesis, Characterization, and Application

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Drilling fluids used in high‐performance well operations often struggle to maintain rheological stability, colloidal dispersion, and filtration control under harsh downhole conditions. This study engineered a multifunctional Fe3O4@Saponin/Cu(II) nanocomposite to address these challenges.
Kassem Al Attabi, Farag M. A. Altalbawy, Hana Ihsan Hassan, Ahmed Salih Sahib, Zahraa Saad Abdulali, Mariem Alwan, Mahmood Jawad, Hiba Mushtaq, Aseel Smerat, Fatimah Pashtun   +9 more
wiley   +1 more source

Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis

Animal Research and One Health, EarlyView.
Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang, Tianqi Jin, Zexin Chen, Ye Gong, Qimin Liu, Zifang Wu, Heran Cao, Yan Li, Yuyan Liu, Tianhao Yang, Zhihong Jiang, Wuzi Dong   +11 more
wiley   +1 more source

Structure-Activity Relationships of <i>closo</i>- and <i>nido</i>-Carborane Erlotinib Analogs: Lipophilicity as a Key Modulator of Anti-Glioma Activity. [PDF]

Pharmaceuticals (Basel)
Dávila B, Vignolo P, Silvarrey M, Benítez A, González Schmidt J, de Arteaga Guidotti C, García MF, Cerecetto H, Couto M.   +8 more
europepmc   +1 more source

TWEAK/Fn14 signaling drives oxidative cardiac injury in systemic lupus erythematosus: Evidence from patient biomarker studies, lupus mouse models, and cardiomyocyte assays

Arthritis &Rheumatology, Accepted Article.
Objective Cardiac involvement is a major cause of morbidity in systemic lupus erythematosus (SLE). Tumor necrosis factor–like weak inducer of apoptosis (TWEAK) is elevated in SLE, but its contribution to lupus‐associated cardiac injury is unclear. We investigated the role of TWEAK/Fn14 signaling in SLE‐related cardiomyopathy and its potential as a ...
Yale Liu, Zhu Yan, Xueting Peng, Meixuan Li, Juan Wang, Yan Zhang, Xiaoqian Hu, Mingzhu Zhou, Kaixuan Ren, Dan Zhang, Xingyi Guo, Yumin Xia, Huanhuan Huo   +12 more
wiley   +1 more source

Activity-Selectivity of Flavonoid Derivatives in Endometriotic Cells. [PDF]

ACS Omega
Gomes KS, Coelho JA, Tesser PEH, Souza DCS, Silva ML, Ferreira EA, Lago JHG, Cerchiaro G.   +7 more
europepmc   +1 more source

A New Era for Using Natural Pigments: The Case of the C50 Carotenoid Called Bacterioruberin

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Haloarchaea are extremophilic microorganisms belonging to the Archaea domain that require high salt concentrations to live, thus inhabiting ecosystems like salty ponds, salty marshes, or extremely salty lagoons. They are more abundant and widely distributed worldwide than initially expected.
Micaela Giani, Elena Valdés, José María Miralles‐Robledillo, Guillermo Martínez, Carmen Pire, Rosa María Martínez‐Espinosa   +5 more
wiley   +1 more source

In silico analysis of <i>Anacardium occidentale</i> phytochemicals: pharmacokinetics, molecular docking, and dynamics of <i>Cryptococcus neoformans</i> enzymes. [PDF]

In Silico Pharmacol
da Silva MVF, Silva J, da Rocha MN, de Morais SM, Marinho ES.   +4 more
europepmc   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

British Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis, Leiah J. Brigitha, Lidwien M. Hanff, Alwin D. R. Huitema, Inge M. van der Sluis, Meta H. M. Diekstra   +5 more
wiley   +1 more source

Lipidation as a post-translational code for protein liquid-liquid phase separation. [PDF]

J Lipid Res
Sani SA, Chytła A, Sztacho M.
europepmc   +1 more source