Results 251 to 260 of about 84,571 (285)
Some of the next articles are maybe not open access.
Phenolic Acids Enzymatic Lipophilization
Journal of Agricultural and Food Chemistry, 2005Lipophilization is the esterification of a lipophilic moiety (fatty acid or fatty alcohol) on different substrates (phenolic acid, sugar, protein, ...), resulting in new molecules with modified hydrophilic/lipophilic balance. This reaction can be obtained chemically or enzymatically using different enzymes. Phenolic acids possess interesting biological
Figueroa-Espinoza, Maria-Cruz +1 more
openaire +5 more sources
2023
Nutraceuticals are considered as components originating from foods, which are publicized to have health promoting effects beyond normal nutritional function due to their specific molecular structures. Certain therapeutic claims still lack further validation using controlled human trials or other long-term efficacy tests, which needs further research ...
Yashu Chen +4 more
openaire +1 more source
Nutraceuticals are considered as components originating from foods, which are publicized to have health promoting effects beyond normal nutritional function due to their specific molecular structures. Certain therapeutic claims still lack further validation using controlled human trials or other long-term efficacy tests, which needs further research ...
Yashu Chen +4 more
openaire +1 more source
Lipophilic Microconstituents of Milk
2007Milk has long been recognized as a source of macro- and micronutrients, immunological components, and biologically active substances, which not only allow growth but also promote health in mammalian newborns. Many milk lipids, lipid-soluble substances, and their digested products are bioactive, including vitamins and vitamin-like substances. Vitamins A,
A. Baldi, L. Pinotti
openaire +2 more sources
Russian Journal of Organic Chemistry, 2015
By reactions of dodecyl and arachidic esters of methylmalonic and dichloroacetic acids with fullerene C60 under the conditions of Bingel–Hirsch reaction the corresponding monosubstituted methanofullerenes well soluble in organic solvents were obtained and characterized.
S. A. Torosyan +3 more
openaire +1 more source
By reactions of dodecyl and arachidic esters of methylmalonic and dichloroacetic acids with fullerene C60 under the conditions of Bingel–Hirsch reaction the corresponding monosubstituted methanofullerenes well soluble in organic solvents were obtained and characterized.
S. A. Torosyan +3 more
openaire +1 more source
Amino Acids, 1994
The lipophilicity (or hydrophobicity) of amino acids is an important property relevant for protein folding and therefore of great interest in protein engineering. For peptides or peptidomimetics of potential therapeutic interest, lipophilicity is related to absorption and distribution, and thus indirectly relates to their bioactivity. A rationalization
H, van de Waterbeemd +2 more
openaire +2 more sources
The lipophilicity (or hydrophobicity) of amino acids is an important property relevant for protein folding and therefore of great interest in protein engineering. For peptides or peptidomimetics of potential therapeutic interest, lipophilicity is related to absorption and distribution, and thus indirectly relates to their bioactivity. A rationalization
H, van de Waterbeemd +2 more
openaire +2 more sources
Lipophilicity of the Nitrophenols
The Journal of Organic Chemistry, 2000The lipophilicity of the nitrophenols, expressed as a water-solvent partition coefficient, P, has been investigated using the solvation equation, log P = c + eE + sS + aA + bB + vV. It is shown that this equation accounts quantitatively for lipophilicity in a selection of water-solvent systems, viz: octanol, 1,2-dichloroethane, and cyclohexane.
, Abraham, , Du, , Platts
openaire +2 more sources
Lipophilicity of Aminopyridazinone Regioisomers
Journal of Agricultural and Food Chemistry, 2003Ten pairs of pyridazinone regioisomers were prepared, and their lipophilicity was described by the logarithm of the octanol/water partition coefficient (log P) determined experimentally and calculated with prediction methods. The 4- and 5-(substituted amino)-3(2H)-pyridazinone regioisomers were synthesized by nucleophilic substitution of one of the ...
Massud A S, Anwair +9 more
openaire +2 more sources
GLYCOSYLTRANSFERASES OF LIPOPHILIC SMALL MOLECULES
Annual Review of Plant Biology, 2006Glycosyltransferases of small molecules transfer sugars to a wide range of acceptors, from hormones and secondary metabolites to biotic and abiotic chemicals and toxins in the environment. The enzymes are encoded by large multigene families and can be identified by a signature motif in their primary sequence, which classifies them as a subset of ...
Bowles, Dianna J +3 more
openaire +3 more sources
Lipophilicity in drug discovery
Expert Opinion on Drug Discovery, 2010The role of lipophilicity in determining the overall quality of candidate drug molecules is of paramount importance. Recent developments suggest that, as well as determining pre-clinical ADMET (absorption, distribution, metabolism, elimination and toxicology) properties, compounds of optimal lipophilicity might have increased chances of success in ...
openaire +3 more sources
Lipases in lipophilization reactions
Biotechnology Advances, 2007Lipases are used in various sectors, as pharmaceutical, food or detergency industry. Their advantage versus classical chemical catalysts is that they exhibit a better selectivity and operate in milder reaction conditions. Theses enzymes can also be used in lipophilization reactions corresponding to the grafting of a lipophilic moiety to a hydrophilic ...
openaire +3 more sources