Results 111 to 120 of about 471,242 (306)
Immunomodulatory effects of 17-O-acetylacuminolide in RAW264.7 cells and HUVECs : involvement of MAPK and NF-κB pathways [PDF]
, 2014 The terpenoid 17-O-acetylacuminolide (AA) was shown to inhibit the production of several inflammatory mediators. However, the mechanisms by which this compound elicited its anti-inflammatory activity remain to be elucidated.
Achoui, Mouna +5 more
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, 2014 Citation: 'lipopolysaccharides' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.L03574 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +1 more source
A colorimetric estimation of lipopolysaccharides
FEBS Letters, 1971 The lipopolysaccharides of Gram-negative bacteria are not confined to cell walls but may accumulate in culture fluids of cells grown under certain conditions [l-3] . Study of this accumulation has been aided by development of a calorimetric estimation for lipopolysaccharides which is specific, sensitive and technically simple in comparison with methods
Janda, J., Work, Elizabeth
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Advanced Materials Technologies, EarlyView.This study presents a new biodegradable coating for titanium implants using a natural antimicrobial peptide, caerin 1.9. Applied via solvent casting, the coating offers sustained antibacterial protection and promotes healing. Tested on 3D‐printed porous titanium scaffolds, it effectively prevented infection—including against resistant bacteria—while ...
Hejie Li +7 more
wiley +1 more source
Advanced Science, EarlyView.Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai +15 more
wiley +1 more source
AnimalsIntestinal inflammation remains one of the most common and severely harmful diseases in intensive farming systems. Ferulic acid (FA) has significant anti-inflammatory properties, but its role in intestinal inflammatory damage remains unclear.
Huan Huang +7 more
doaj +1 more source
Bisdemethoxycurcumin and Its Cyclized Pyrazole Analogue Differentially Disrupt Lipopolysaccharide Signalling in Human Monocyte-Derived Macrophages [PDF]
, 2018 open11noSeveral studies suggest that curcumin and related compounds possess antioxidant and anti-inflammatory properties including modulation of lipopolysaccharide- (LPS-) mediated signalling in macrophage cell models. We here investigated the effects of
core +1 more source
Coagulation Activation by Lipopolysaccharides
Clinical and Applied Thrombosis/Hemostasis, 2007 Lipopolysaccharides at approximate plasma reactivities >3 ng/mL or β-glucans at >0.5-1 μg/mL are toxic for human blood; lipopolysaccharide interacts with membrane components of susceptible cells (eg, monocytes) activating phospholipase A2 that destroys the cell membrane.
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Advanced Science, EarlyView.This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang +13 more
wiley +1 more source
Annals of Mechnikov's Institute, 2020 Last decades, antimicrobial peptides (AMPs) are the subject of intense investigations aimed to develop effective drugs against extremely resistant nosocomial bacterial pathogens (especially Gram-negative bacteria).
Yu Lisnyak
doaj