Results 31 to 40 of about 826,002 (242)

Quantitation of plasma mevalonic acid using gas chromatography-electron capture mass spectrometry.

Journal of Lipid Research, 1991
Circulating concentrations of mevalonic acid (MVA) change in parallel with, and may be used as a marker of cholesterol biosynthesis. Plasma MVA levels have been quantified using a sensitive and specific capillary gas chromatography-electron capture mass ...
A Scoppola, VM Maher, GR Thompson, NB Rendell, GW Taylor   +4 more
doaj   +1 more source

Causal relevance of blood lipid fractions in the development of carotid atherosclerosis: Mendelian randomization analysis. [PDF]

, 2013
BACKGROUND: Carotid intima-media thickness (CIMT), a subclinical measure of atherosclerosis, is associated with risk of coronary heart disease events. Statins reduce progression of CIMT and coronary heart disease risk in proportion to the reduction in ...
Baldassarre, Damiano, Casas, Juan-Pablo, de Faire, Ulf, Deanfield, John, Drenos, Fotios, Gertow, Karl, Gigante, Bruna, Hamsten, Anders, Hingorani, Aroon D, Holmes, Michael V, Humphries, Steve E, Kivimaki, Mika, Kumari, Meena, Langenberg, Claudia, Sennblad, Bengt, Shah, Sonia, Strawbridge, Rona J, Swerdlow, Daniel I, Talmud, Philippa J, Tremoli, Elena, Veglia, Fabrizio, Wareham, Nick, Whittaker, John   +22 more
core   +1 more source

Adipose tissue cholesteryl ester transfer protein mRNA in response to probucol treatment: cholesterol and species dependence

Journal of Lipid Research, 1993
Probucol treatment results in an increase in plasma concentrations of cholesteryl ester transfer protein (CETP) which may account, in part, for the effects of this agent on plasma concentrations of HDL cholesterol. We have examined the mechanism by which
EM Quinet, P Huerta, D Nancoo, AR Tall, YL Marcel, R McPherson   +5 more
doaj   +1 more source

Effect of a novel nutraceutical combination on serum lipoprotein functional profile and circulating PCSK9 [PDF]

, 2017
BACKGROUND: A beneficial effect on cardiovascular risk may be obtained by improving lipid-related serum lipoprotein functions such as high-density lipoproteins (HDLs) cholesterol efflux capacity (CEC) and serum cholesterol loading capacity (CLC) and by ...
Adorni, Maria Pia, Bernini, Franco, Ferri, Nicola, Izzo, Raffaele, Marchiano, Silvia, Rozza, Francesco, Trimarco, Valentina, Zimetti, Francesca   +7 more
core   +3 more sources

Lipoprotein apheresis to treat elevated lipoprotein (a) [PDF]

Journal of Lipid Research, 2016
An elevated plasma concentration of lipoprotein (a) [Lp(a)] is an independent risk factor for cardiovascular disease. Life style modification and currently available drugs either fail to effectively lower plasma Lp(a) levels or do not result in clinical benefit. However, lipoprotein apheresis is very efficient in decreasing Lp(a) concentrations.
Elisa Waldmann, Klaus G. Parhofer
openaire   +2 more sources

Bacterial expression and site-directed mutagenesis of a functional recombinant apolipoprotein.

Journal of Lipid Research, 1995
To facilitate structure-function studies of Manduca sexta apolipophorin III (apoLp-III), its nucleotide coding sequence was cloned from a fat body cDNA library by in vitro DNA amplification.
R O Ryan, D Schieve, M Wientzek, V Narayanaswami, K Oikawa, C M Kay, L B Agellon   +6 more
doaj   +1 more source

Hepatitis C virus relies on lipoproteins for its life cycle [PDF]

, 2016
Hepatitis C virus (HCV) infects over 150 million people worldwide. In most cases, HCV infection becomes chronic causing liver disease ranging from fibrosis to cirrhosis and hepatocellular carcinoma.
Alonzi, Tonino, DI CAPRIO, Giorgia, Fimia, Gian Maria, Grassi, Germana, Ippolito, Giuseppe, Tripodi, Marco   +5 more
core   +1 more source

Characterization of mutations in the low density lipoprotein (LDL)-receptor gene in patients with homozygous familial hypercholesterolemia, and frequency of these mutations in FH patients in the United Kingdom

Journal of Lipid Research, 1996
Mutations in the gene for the low density lipoprotein (LDL) receptor have been identified in 15 patients with homozygous familial hypercholesterolemia (FH).
J C Webb, X M Sun, S N McCarthy, C Neuwirth, G R Thompson, B L Knight, A K Soutar   +6 more
doaj   +1 more source

Effects of Diet Composition and Insulin Resistance Status on Plasma Lipid Levels in a Weight Loss Intervention in Women. [PDF]

, 2016
BackgroundOptimal macronutrient distribution of weight loss diets has not been established. The distribution of energy from carbohydrate and fat has been observed to promote differential plasma lipid responses in previous weight loss studies, and insulin
Flatt, Shirley W, Heath, Dennis D, Le, Tran, Natarajan, Loki, Pakiz, Bilge, Quintana, Elizabeth L, Rana, Brinda K, Rock, Cheryl L   +7 more
core   +3 more sources

Phosphatidylcholine biosynthesis is required for secretion of truncated apolipoprotein Bs from McArdle RH7777 cells only when a neutral lipid core is formed

Journal of Lipid Research, 1997
Decreased phosphatidylcholine biosynthesis inhibits the secretion of very low density lipoproteins from hepatocytes (Yao, Z. and D. E. Vance. 1988. J. Biol. Chem. 263: 2998-3004).
P S Vermeulen, S Lingrell, Z Yao, D E Vance   +3 more
doaj   +1 more source