Results 151 to 160 of about 24,826 (263)
Lipoprotein(a) and acute myocardial infarction: Differential risk across age and sex subgroups. [PDF]
Liu Z +5 more
europepmc +1 more source
Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen +4 more
wiley +1 more source
reservedPresupposti dello studio. Elevate concentrazioni plasmatiche di lipoproteina (a) [Lp(a)] costituiscono un determinante causale e indipendente di aterosclerosi e delle sue complicanze, con un incremento del rischio cardiovascolare clinicamente ...
SIVIERO, ANNA CATERINA
core
ABSTRACT Apolipoprotein B (ApoB) is a key marker of atherogenic lipoprotein burden, but conventional plasma‐based testing requires venous sampling and centralized laboratory infrastructure. Dried blood spot (DBS) sampling offers a minimally invasive alternative suitable for decentralized settings.
Bronwyn Pitampersad +4 more
wiley +1 more source
The CHG index, derived from total cholesterol, high‐density lipoprotein, and fasting blood glucose, was associated with 90‐day functional outcomes after acute ischemic stroke. ABSTRACT Background: Acute ischemic stroke (AIS) is a major cause of global disability and mortality.
Xinyue Yuan +5 more
wiley +1 more source
The Impact of Current and Emerging Therapies on Lipoprotein(a). [PDF]
Nicholls SJ, Nelson AJ.
europepmc +1 more source
MIR503HG was downregulated in sepsis and sepsis‐induced cardiac dysfunction (SICD) and served as a diagnostic biomarker. Overexpression of MIR503HG attenuated myocardial injury and systemic inflammation in a septic rat model. Mechanistically, MIR503HG acted as a ceRNA by sponging miR‐497‐5p to upregulate BDNF, revealing a protective MIR503HG/miR‐497‐5p/
Pingping Qi +5 more
wiley +1 more source
Feature importance for predicting multiple diabetes complications based on a Stacking‐Classifier Chain model. ABSTRACT Background Type 2 diabetes mellitus (T2DM) leads to severe microvascular and macrovascular complications. Traditional single‐label prediction models fail to capture their co‐occurring nature.
Maryam Zamani +3 more
wiley +1 more source
LPS triggers neuroinflammation within the central nervous system. Conversely, the activation of LRP1 by SP16 mitigates insulin resistance, improves glucose metabolism, and facilitates the polarization of microglia toward an anti‐inflammatory M2‐like phenotype, which collectively contribute to the restoration of cognitive function.
Mengyao Qu +9 more
wiley +1 more source
Long‐term trends in metabolic profiles across Chinese birth cohorts: A real‐world big data analysis
• Younger generations (1980s–1990s) exhibit higher fasting glucose and rebounding total cholesterol and low‐density lipoprotein cholesterol, alongside declining high‐density lipoprotein cholesterol and triglycerides compared to 1930s–1970s cohorts.
Ying Xiong +7 more
wiley +1 more source

