Results 171 to 180 of about 24,826 (263)

DAMP Laden Extracellular Vesicles From the Airways of Patients With Severe SARS‐CoV‐2 Respiratory Infection Compromise Inflammation and Cellular Metabolism

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
Extracellular vesicles from severe COVID‐19 airways carry depleted miRNAs and elevated DAMPs, reprogramming monocytes toward senescence, impaired metabolism, and predominantly reduced cytokine responses. However, they drive excess IL‐8 production, amplifying neutrophil recruitment and dysfunctional inflammation across the respiratory tract.
April Rees, Oliver Richards, Molly E Raikes, Megan Chambers, Sophie G Reed, Ceri Battle, Hannah Toghill, Luke Newey, Tyler J Joseph, Haiyan An, Hui Zhang, Iain Perry, Jason Webber, Nicholas Jones, Catherine A Thornton   +14 more
wiley   +1 more source

Association of Elevated Lipoprotein(a) Levels with Major Adverse Cardiovascular Events in Non-Diabetic Patients with Acute Myocardial Infarction: A Cohort Study from Bosnia and Herzegovina. [PDF]

Med Sci (Basel)
Jamaković M, Šljivo A, Durak-Nalbantić A, Ljuca F, Bajrić M, Hukeljić-Berberović B.   +5 more
europepmc   +1 more source

RNAs Associated With Bacterial Outer Membrane Vesicles: Structural Insights Into Surface Composition

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
This work uncovers a new layer of bacterial communication. We show that RNAs, aided by the Hfq RNA‐chaperone, are not only packed inside Gram negative Outer Membrane Vesicles (OMVs) but can also be embedded in their membranes. This suggests that bacteria may use surface‐exposed RNAs to directly interact with host cells. Overall, our results broaden the
Kevin Mosca, Florian Turbant, Wafa Achouak, Frank Wien, Véronique Arluison   +4 more
wiley   +1 more source

Managing Progressive Atherosclerotic Cardiovascular Disease in a Patient with Elevated Lipoprotein(a). [PDF]

Anatol J Cardiol
Yurtseven E, Tokgözoğlu L.
europepmc   +1 more source

Association of Polygenic Risk Scores With Aortic Valve Calcium: The Multi-Ethnic Study of Atherosclerosis. [PDF]

J Am Heart Assoc
Whelton SP, Yao J, Clish C, Wood AC, Taylor KD, Blaha MJ, Budoff M, Marrero N, Thanassoulis G, Post WS, Guo X, Rotter JI.   +11 more
europepmc   +1 more source

Label‐Free Clustering Analysis Platform Drives Cascaded Workflow for Scalable Production of Therapeutic Extracellular Vesicles

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
ABSTRACT Extracellular vesicles (EVs) have emerged as highly promising natural nanomedicines and nanocarriers, holding transformative potential for the treatment of various diseases. However, the lack of rapid and comprehensive characterization techniques for EV preparation analysis, coupled with the absence of efficient quality control methods ...
Jing Zhou, Ping Chen, Xin Chen, Xu Xiao, Haonan Di, Yunyun Hu, Yarong Zhen, Xiaomei Yan   +7 more
wiley   +1 more source

Sex Differences in Lipids and Lipoproteins and Their Relationship With Cardiovascular Disease: A Prospective Study of UK Biobank Participants. [PDF]

J Am Heart Assoc
Kelly RK, Harris K, Muntner P, Woodward M.   +3 more
europepmc   +1 more source

Endothelial Integrin‐Linked Kinase (ILK) Deficiency Promotes Endothelial Activation and Cardiovascular Dysfunction via Receptor Interacting Protein Kinase‐1 (RIPK1) Enriched‐Extracellular Vesicle Signalling

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
Endothelial ILK loss drives RIPK1‐enriched EVs that propagate systemic endothelial activation and cardiovascular remodelling. EV cargo remodelling induces early endothelial injury, microvascular dysfunction and chronic cardiac alterations through a RIPK1 dependent pathway.
Alberto Cook‐Calvete, María Delgado‐Marín, Sara Jorquera Ortega, Silvia Moreta, Mercedes Castro‐Pinto, José López‐Menendez, Blanca Rodríguez‐Fernandez, Julia García‐García, Carlos Zaragoza, Marta Saura   +9 more
wiley   +1 more source

Population specific risk thresholds for lipoprotein(a): implications from angiographic data in Central Asia. [PDF]

Front Med (Lausanne)
Mussagaliyeva A, Tuleutayev R, Zhangelova S, Kapsultanova D, Akhmentayeva D, Zhanuzak A, Altybayeva S, Rakisheva A.   +7 more
europepmc   +1 more source

Cell Envelope Remodeling and Lipid Metabolism Coordinate Extracellular Vesicle Output in Mycobacterium Tuberculosis

Journal of Extracellular Biology, Volume 5, Issue 6, June 2026.
ABSTRACT Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a leading global cause of death due to the pathogen's highly adaptive physiology and its ability to manipulate host immunity. Despite extensive study, our understanding of Mtb biology during infection remains incomplete, limiting the development of new diagnostics ...
José L. Serrano‐Mestre, Laura Lerma, Lucía Vázquez‐Iniesta, Vivian C. Salgueiro‐Toledo, Ainhoa Palacios, Sogol Alebouyeh, Andrea Doddi, Felix Elortza, Mikel Azkargorta, Leticia Sampedro, Estibaliz Atondo, Miguel Ángel Pacual‐Itoiz, Oren Mayer, Torin Westwood, William R. Jacobs Jr, Rafael Prados‐Rosales   +15 more
wiley   +1 more source