Results 161 to 170 of about 21,997 (216)
Some of the next articles are maybe not open access.
The Lp lipoprotein in Japanese
Clinical Genetics, 1978The Lp gene frequency is estimated to be 0.083 in Japanese, but with our method of assay the evidence favoring a major locus is marginal. The sinking pre‐β band is significantly associated with elevated cholesterol and depressed triglyceride. The biological significance of these observations is discussed.
N E, Morton +3 more
openaire +2 more sources
Lipoprotein Lp(a) and Atherothrombotic Disease
Archives of Medical Research, 2000High plasma concentrations of lipoprotein (a) [Lp(a)] are now considered a major risk factor for atherosclerosis and cardiovascular disease. This effect of Lp(a) may be related to its composite structure, a plasminogen-like inactive serine-proteinase, apoprotein (a) [apo(a)], which is disulfide-linked to the apoprotein B100 of an atherogenic low ...
A, de la Peña-Díaz +2 more
openaire +2 more sources
Studies on the Lp(a)-lipoprotein of human serum
Humangenetik, 1972Lp(a)-lipoprotein of human serum, when isolated by ultracentrifugation and gelfiltration on Sepharose 4 B, may disaggregate into several components either spontaneously or by mild treatment with detergents:
G, Utermann, K, Lipp, H, Wiegandt
openaire +2 more sources
Lp(a) lipoprotein: An overview
Chemistry and Physics of Lipids, 1990The Lp(a) lipoprotein, a distinct class of serum lipoproteins, was detected in 1962. It consists of an LDL particle to which a long polypeptide chain is attached by a disulfide bridge. The level of Lp(a) lipoprotein is genetically determined. Single locus control was suggested already in the very first report, and this has been conclusively confirmed ...
openaire +2 more sources
Oxidation of lipoprotein Lp(a). A comparison with low-density lipoproteins
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1991Aimed at identifying possible mechanisms of the suggested high atherogenicity of Lp(a), its susceptibility for Cu(II)-induced oxidation was studied and compared with that of LDL. Since the content of antioxidants as well as the fatty acid pattern of a lipoprotein greatly affects its oxidizability, Lp(a) and LDL were characterized first with respect to ...
W, Sattler +3 more
openaire +2 more sources
Genetics of the quantitative Lp(a) lipoprotein trait
Human Genetics, 1988The Lp(a) lipoprotein is a complex particle composed of a low density lipoprotein (LDL)-like lipoprotein and the disulfide bonded Lp(a) glycoprotein. The complex represents a quantitative genetic trait. SDS gel electrophoresis under reducing conditions of sera followed by immunoblotting with affinity-purified polyclonal anti-Lp(a) demonstrated inter ...
G, Utermann +4 more
openaire +2 more sources
Lipoprotein Lp(a) and the risk for myocardial infarction
Atherosclerosis, 1981Abstract The serum lipoprotein Lp(a) concentration was measured in 76 male post-myocardial infarction (MI) patients aged between 40 and 60 years, and in 107 control subjects of the same age and sex. Quantitation was performed by the Laurell technique. It was sensitive in the range 1–60 mg/dl with a day to day C. V. of less than 4%.
G M, Kostner +5 more
openaire +2 more sources
Lp(a) Lipoprotein in Cerebrovascular Disease and Dementia
Psychiatry and Clinical Neurosciences, 1987Abstract: Lp(a) lipoprotein has been considered an independent risk factor in the development of coronary heart disease (CHD). We examined the role of Lp(a) in patients with cerebrovascular disease (CVD) and those with dementia.The Lp(a) concentration in patients with CHD, those with cerebral infarction due to a large artery occlusion and those with ...
K, Urakami, T, Mura, K, Takahashi
openaire +2 more sources
Uptake of Lp(a) lipoprotein by cultured fibroblasts
Biochemical and Biophysical Research Communications, 1981Summary Lp(a) lipoprotein is bound and taken up by cultured human fibroblasts and increases cell cholesterol content and cholesterol esterification. The increase in cell cholesterol content and cholesterol esterification in low density lipoprotein receptor negative cells was minimal, which suggests that Lp(a) lipoprotein was taken up by the low ...
C H, Floren, J J, Albers, E L, Bierman
openaire +2 more sources
Lp(a) lipoprotein in cardiovascular disease
Atherosclerosis, 1994The article summarizes the increased knowledge about the enigmatic Lp(a) lipoprotein and its clinical importance over the past 20 years. The mode of inheritance, the unique features of Lp(a) composition and structure and the unusual distribution of the mainly genetically determined plasma Lp(a) levels are discussed.
openaire +2 more sources