Results 111 to 120 of about 93,526 (325)

Effects of high sucrose diet, gemfibrozil, and their combination on plasma paraoxonase 1 activity and lipid levels in rats [PDF]

, 2010
We investigated the influence of high sucrose diet (HSD) after 3 or 5 weeks of administration on paraoxonase 1 (PON1) activity in plasma of normolipidemic rats and the relationship between serum PON1 activity, triacylglycerides (TGs), HDL and total ...
Bradamante, Vlasta, Lucić Vrdoljak, Ana, Macan, Marija, Radić, Božica, Vrkić, Nada   +4 more
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Population Pharmacokinetics and Exposure‐Response Modeling for Evinacumab in Children, Adolescents, and Adults With Homozygous Familial Hypercholesterolemia

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Evinacumab, an angiopoietin‐like 3 (ANGPTL3) inhibitor, significantly reduces low‐density lipoprotein cholesterol (LDL‐C), independent of low‐density lipoprotein receptor, in patients with homozygous familial hypercholesterolemia (HoFH). A population pharmacokinetic (PK)/pharmacodynamic (PD) model was previously developed to characterize ...
Sébastien Bihorel, Robert Dingman, Jeanne Mendell, Yuhuan Wang, Poulabi Banerjee, Robert Pordy, John D. Davis, A. Thomas DiCioccio, Lutz Harnisch   +8 more
wiley   +1 more source

Lipoprotein metabolism in hepatic lipase deficiency: studies on the turnover of apolipoprotein B and on the effect of hepatic lipase on high density lipoprotein.

Journal of Lipid Research, 1988
Hepatic lipase deficiency produces significant distortion in the plasma lipoprotein profile. Particles with reduced electrophoretic mobility appear in very low density lipoprotein (VLDL).
T Demant, L A Carlson, L Holmquist, F Karpe, P Nilsson-Ehle, C J Packard, J Shepherd   +6 more
doaj   +1 more source

Plasmapheresis in Acute Hypertriglyceridemia‐Induced Pancreatitis—The PHIP‐JuGa‐Study

United European Gastroenterology Journal, EarlyView.
ABSTRACT Background and Aims The incidence of acute pancreatitis is increasing in the Western world. About 10% of cases are caused by hypertriglyceridemia. Plasmapheresis was shown to reduce serum triglyceride (TG) levels, and current apheresis guidelines recommend its use in severe acute hypertriglyceridemia‐induced pancreatitis (HIP).
Jonas J. Staudacher, Elisabeth Blüthner, Katharina Murillo, Manja Boldt, Karim Hamesch, Leah Kruse, Sabrina Sulzer, Christoph Ammer‐Herrmenau, Yvonne Huber, Julia Weinmann‐Menke, Charlotte Kramer, Jakob Garbe, Rene Wilke, Marcus M. Mücke, Myriam W. Heilani, Elisabeth Orgler‐Gasche, Marlies Vornhülz, Georg Beyer, Lara Wiesehahn, Annekatrin Schwanstecher, Marcus Hollenbach, Hendrik Luxenburger, Dominik Bettinger, Sophie Schlosser‐Hupf, for the JuGa study group   +24 more
wiley   +1 more source

Measurement of lipoprotein lipase activity in post heparin plasma: description of technique*

Journal of Lipid Research, 1961
A method has been described for the quantitative assay of lipoprotein lipase activity in post heparin plasma. The conditions of the assay were subjected to critical study. The technique described permits the reaction to proceed in the test tube as a zero
Fred Kern, Jr., Laura Steinmann, Bob B. Sanders   +2 more
doaj   +1 more source

Chromosome‐level genome assembly and population genomic analysis provide insights into the genetic diversity and adaption of Schizopygopsis younghusbandi on the Tibetan Plateau

Integrative Zoology, EarlyView.
We have constructed the chromosome‐scale genome and investigated the evolutionary genomics of Schizopygopsis younghusbandi, a fish species native to the Yarlung Tsangpo River on the Tibetan Plateau. Our study indicated that this species diverged from other Schizothoracine fish approximately 4.2 million years ago, during the Neogene Tibetan uplift ...
Chaowei ZHOU, Yan ZHOU, Luohao XU, Fei LIU, Luo LEI, He GAO, Junting LI, Suxing FU, Yuting DUAN, Yougang TAN, Weihua MAO, Qiming WANG, Rongzhu ZHOU, Shijun XIAO, Chuan LIU, Haiping LIU   +15 more
wiley   +1 more source

Lipid content and lipoprotein lipase activity in skeletal muscle of lactating and weaned rats

Journal of Lipid Research, 1993
The aim of the investigation was to study the changes in lipid content and lipoprotein lipase (LPL) activity of skeletal muscle of lactating and weaned rats, in order to gain insight on the role of skeletal muscle in the metabolism of triacylglycerols ...
M Del Prado, R Ramos, H Hernández-Montes, S Villalpando   +3 more
doaj   +1 more source

Studies of Fat Lipolysis by Post-Heparin Human Plasma Lipoprotein Lipase and by Human Pancreatic Lipase [PDF]

, 1959
Hyman Engelberg
openalex   +1 more source

Milk Lipoprotein Lipases: A Review

Journal of Dairy Science, 1976
Lipoprotein lipase activity has been found in the milks from severals species where it is assumed to result from leakage from the mammary gland into milk. The function of the enzyme in the gland is apparently to assist in the transfer of blood lipoprotein triacylglycerol fatty acids into milk triacylglycerols.
Robert G. Jensen, R.E. Pitas
openaire   +3 more sources

Insulin response and changes in composition of non-esterified fatty acids in blood plasma of middle-aged men following isoenergetic fatty and carbohydrate breakfasts [PDF]

, 2000
It was previously shown that a high plasma concentration of non-esterified fatty acids (NEFA) persisted after a fatty breakfast, but not after an isoenergetic carbohydrate breakfast, adversely affecting glucose tolerance.
Carpenter, KLH, Fletcher, RJ, Frape, DL, Freeman, MA, Palmer, CR, Williams, NR   +5 more
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