Results 61 to 70 of about 23,180 (193)

Clinical and laboratory evaluation of patients with visceral leishmaniasis undergoing different therapeutic regimens of liposomal amphotericin B

Acta Scientiarum. Health Sciences
Visceral Leishmaniasis (VL) is an infectious disease caused by protozoa of the Leishmania genus and is transmitted to humans by the bite of infected female Lutzomyia sandflies.
Fernanda Santana da Silva, Elder Andrade Oliveira Filho , Maria Luísa Santos Fernandes, Gabriel Donner Oliveira, Victor Hugo Dantas Guimarães   +4 more
doaj   +1 more source

Monodentate Phosphine Modulation in Cyclometallated Platinum(II) Complexes for Antileishmanial, Antiviral, and Antitumor Applications

ChemMedChem, Volume 21, Issue 4, 25 February 2026.
Schematic representation depicting the influence of phosphine ligand identity on the biological and physicochemical characteristics of Pt(II) complexes: PTA promotes antileishmanial activity, PPh2(Php–COOH) strengthens antiviral activity, and TCEP enhances fluorescence.
Antonio A. de Oliveira‐Neto, Gustavo Clauss, Jennyfer Castro, Marcus S. A. Garcia, Natasha M. Cassani, Bruna C. Sandim, Ana Laura C. Oliveira, Stephanie P. B. Reyes, Nádija N. P. da Silva, Fillipe V. Rocha, Ana C. G. Jardim, Danilo C. Miguel, Camilla Abbehausen   +12 more
wiley   +1 more source

Noncovalent complexation of amphotericin-B with Poly(α-glutamic acid).

, 2013
A noncovalent complex of amphotericin B (AmB) and poly(α-glutamic acid) (PGA) was prepared to develop a safe and stable formulation for the treatment of leishmaniasis. The loading of AmB in the complex was in the range of ∼20-50%.
Brocchini, Stephen, Croft, Simon L, Les, Karolina A, Mohamed-Ahmed, Abeer HA, Seifert, Karin   +4 more
core   +1 more source

AMBIsome Therapy Induction OptimisatioN (AMBITION): High dose AmBisome for cryptococcal meningitis induction therapy in sub-Saharan Africa: economic evaluation protocol for a randomised controlled trial-based equivalence study. [PDF]

, 2019
INTRODUCTION: Cryptococcal meningitis is responsible for around 15% of all HIV-related deaths globally. Conventional treatment courses with amphotericin B require prolonged hospitalisation and are associated with multiple toxicities and poor outcomes.
Alufandika, M, Bango, F, Boulware, DR, Boyer-Chammard, T, Chawinga, C, Chen, T, Dziwani, E, Gondwe, E, Harrison, TS, Hlupeni, A, Hosseinipour, MC, Jaffar, S, Jarvis, JN, Kanyama, C, Lalloo, DG, Lawrence, DS, Lortholary, O, Loyse, A, Maheswaran, H, Meintjes, G, Meya, DB, Molloy, SF, Mosepele, M, Muthoga, C, Muzoora, CK, Mwandumba, H, Ndhlovu, CE, Niessen, LW, Ponatshego, PL, Rajasingham, R, Sayed, S, Shamu, S, Shiri, T, Tsholo, K, Tugume, L, Wang, D, Williams, D, Youssouf, N   +37 more
core   +4 more sources

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

Advanced Science, Volume 13, Issue 7, 3 February 2026.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source

Cryptococcal meningitis: improving access to essential antifungal medicines in resource-poor countries [PDF]

, 2013
Cryptococcal meningitis is the leading cause of adult meningitis in sub-Saharan Africa, and contributes up to 20% of AIDS-related mortality in low-income and middle-income countries every year.
Bicanic, Tihana, Chiller, Tom, Easterbrook, Philippa, Ford, Nathan, Govender, Nelesh, Harrison, Thomas S, Loyse, Angela, Roy, Monika, Thangaraj, Harry   +8 more
core   +1 more source

Lipsosomal amphotericin B: a review of its properties, function, and use for treatment of cutaneous leishmaniasis

Research and Reports in Tropical Medicine, 2019
Mohammad Reza Shirzadi1,21Center for Communicable Diseases Control, Ministry of Health and Medical Education, Tehran, Iran; 2Center for Research of Endemic Parasites of Iran (CREPI), Tehran University of Medical Science, Tehran, IranAbstract: The genus ...
Shirzadi MR
doaj  

Successful outcome of disseminated mucormycosis in a 3-year-old child suffering from acute leukaemia: the role of isavuconazole? A case report

BMC Pharmacology and Toxicology, 2018
Background The use of isavuconazole is approved for the management of invasive aspergillosis and mucormycosis, only in adults, as no paediatric pharmacology studies have been reported to date.
Marjorie Cornu, Bénédicte Bruno, Séverine Loridant, Pauline Navarin, Nadine François, Fanny Lanternier, Elisa Amzallag-Bellenger, François Dubos, Françoise Mazingue, Boualem Sendid   +9 more
doaj   +1 more source

Molecular Identification and Evaluation of Resistance to Antifungal Drugs in Candida Species Isolated From Diaper Rash of Neonates

Health Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background Diaper dermatitis, also recognized as diaper rash, is one of the most frequent skin conditions in neonates. Materials and Methods A total of 100 babies participated in the study. Eligibility included neonates aged 5–28 days and full‐time diaper wearers.
Fariba Shirvani, Mahsa Fattahi, Abdollah Karimi, Shahnaz Armin, Seyed Alireza Fahimzad, Sedigheh Rafiei Tabatabaei, Roxana Mansour Ghanaei, Fatemeh Fallah, Alireza Firooz, Shahrzad Tabatabaee, Mitra Radfar, Dorsa Kalani, Hossein Foroozan, Afagh firoozgaeean Galoogah, Pegah Tamimi   +14 more
wiley   +1 more source

Anfotericina B forma liposómica: un perfil farmacocinético exclusivo. Una historia inacabada. [PDF]

, 2012
Amphotericin B in its lipid formulation continues to be the reference drug in the treatment of systemic fungal infections despite the time elapse since the development of this compound.
Azanza, J.R. (José Ramón), Barberan, J. (Jose)   +1 more
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