Results 51 to 60 of about 1,901 (164)

The use of bilateral transversus abdominis plane blocks with liposomal bupivacaine on postoperative cesarean delivery patients during COVID-19 pandemic is associated with reduced narcotics use and reduced length of stay

open access: yesWomen's Health, 2021
Background: The use of transversus abdominis plane blocks has been previously shown in both large-scale studies and our own institution to significantly reduce postoperative pain and opioid use.
Dennis E Feierman   +7 more
doaj   +1 more source

Transversus abdominis plane block with liposomal bupivacaine versus standard bupivacaine for postoperative analgesia in elective cesarean section: a systematic review and meta-analysis

open access: yesFrontiers in Anesthesiology
BackgroundTransversus abdominis plane (TAP) block with bupivacaine is commonly used for analgesia after cesarean deliveries. Liposomal bupivacaine has been incorporated into TAP blocks to potentially prolong analgesic effects and reduce opioid use ...
Matheus Requena Escobar   +5 more
doaj   +1 more source

PI3K/AKT/mTOR Axis in Cancer: From Pathogenesis to Treatment

open access: yesMedComm, Volume 6, Issue 8, August 2025.
The PI3K/AKT/mTOR signaling axis is crucial in cancer progression, regulating cell growth, survival, and metabolism. Often hyperactivated through mutations or loss of tumor suppressors such as PTEN, this pathway promotes cancer cell proliferation and survival by inhibiting apoptosis and activating mTOR, which drives protein synthesis and suppresses ...
Mingyang Jiang   +10 more
wiley   +1 more source

Multimodal Analgesia in Breast Surgical Procedures: Technical and Pharmacological Considerations for Liposomal Bupivacaine Use

open access: yesPlastic and Reconstructive Surgery, Global Open, 2017
Enhanced recovery after surgery is a multidisciplinary perioperative clinical pathway that uses evidence-based interventions to improve the patient experience as well as increase satisfaction, reduce costs, mitigate the surgical stress response ...
Anoushka M. Afonso, MD   +9 more
doaj   +1 more source

PROSPECTS FOR RAISING EFFICIENCY OF POSTOPERATIVE ANESTHESIA DURING NEURAXIAL BLOCK (REVIEW OF LITERATURE)

open access: yesActa Biomedica Scientifica, 2017
This article presents the literature data on existing methods of postoperative pain relief. The technique of extended micro-catheter postoperative analgesia is discussed, as well as advantages and disadvantages of the method.
A. V. Zharnikov, A. N. Plekhanov
doaj   +1 more source

Mesenchymal Stem Cells‐Derived Extracellular Vesicles Mimetics as Osteoinductive Mediators for Bone Healing

open access: yesAdvanced Functional Materials, Volume 35, Issue 29, July 17, 2025.
Mesenchymal stem cell‐derived nanoghosts (MSC‐NGs) mimic naturally secreted extracellular vesicles (MSC‐EVs) in structure and physicochemical properties but can be synthesized at more translatable yields. As osteogenic agents, MSC‐NGs demonstrate superior outcomes compared to MSC‐EVs.
Antoine Karoichan   +4 more
wiley   +1 more source

Nanoparticle Therapeutics in Clinical Perspective: Classification, Marketed Products, and Regulatory Landscape

open access: yesSmall, Volume 21, Issue 29, July 24, 2025.
This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai   +5 more
wiley   +1 more source

Case Report: Intestinal Diverticulum in a Golden Retriever

open access: yesVeterinary Medicine and Science, Volume 11, Issue 4, July 2025.
A 1‐year‐old female spayed Golden Retriever presented with a 2‐day history of vomiting and a chronic 4‐month history of intermittent diarrhoea. Owners elected to pursue exploratory laparotomy where a firm, tan, irregular structure was observed in the right caudal abdomen with a small adhesion to an adjacent loop of jejunum. The structure was removed en
Emily Eppler, Alyssa Motz
wiley   +1 more source

Effect of pre-incisional infiltration with bupivacaine liposome for postoperative pain in patients undergoing acoustic neuroma surgery: study protocol for a prospective, double-blind, randomized controlled study

open access: yesFrontiers in Medicine
BackgroundPost-craniotomy pain, relatively common in neurosurgery, is often inadequately managed. Preincisional infiltration with ropivacaine provides effective analgesia for post-craniotomy pain, although its duration of action is limited.
Maolin Ran   +7 more
doaj   +1 more source

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