Results 21 to 30 of about 244,267 (315)

Multiscale Dynamics of Lipid Vesicles in Polymeric Microenvironment [PDF]

Membranes 2022, 12(7), 640, 2022
Understanding dynamic and complex interaction of biological membranes with extracellular matrices plays a crucial role in controlling a variety of cell behavior and functions, from cell adhesion and growth to signaling and differentiation. Tremendous interest in tissue engineering has made it possible to design polymeric scaffolds mimicking the ...
arxiv   +1 more source

Synthesis and Antioxidant Activity of Caffeic Acid Derivatives

Molecules, 2018
A series of caffeic acid derivatives were synthesized via a modified Wittig reaction which is a very important tool in organic chemistry for the construction of unsaturated carbon–carbon bonds.
Katarzyna Sidoryk, Anna Jaromin, Nina Filipczak, Piotr Cmoch, Marcin Cybulski   +4 more
doaj   +1 more source

Polymer-Modified Liposomes for Drug Delivery: From Fundamentals to Applications

Pharmaceutics, 2022
Liposomes are highly advantageous platforms for drug delivery. To improve the colloidal stability and avoid rapid uptake by the mononuclear phagocytic system of conventional liposomes while controlling the release of encapsulated agents, modification of ...
Yifeng Cao, Xinyan Dong, Xuepeng Chen
doaj   +1 more source

Dielectric properties and lamellarity of single liposomes measured by in-liquid scanning dielectric microscopy

Journal of Nanobiotechnology, 2021
Liposomes are widely used as drug delivery carriers and as cell model systems. Here, we measure the dielectric properties of individual liposomes adsorbed on a metal electrode by in-liquid scanning dielectric microscopy in force detection mode.
Martina Di Muzio, Ruben Millan-Solsona, Aurora Dols-Perez, Jordi H. Borrell, Laura Fumagalli, Gabriel Gomila   +5 more
doaj   +1 more source

The Vacuolar Pathway in Macrophages Plays a Major Role in Antigen Cross-Presentation Induced by the Pore-Forming Protein Sticholysin II Encapsulated Into Liposomes

Frontiers in Immunology, 2018
Cross-presentation is an important mechanism for the differentiation of effector cytotoxic T lymphocytes (CTL) from naïve CD8+ T-cells, a key response for the clearance of intracellular pathogens and tumors.
Yoelys Cruz-Leal, Daniel Grubaugh, Catarina V. Nogueira, Isbel Lopetegui-González, Anaixis del Valle, Felipe Escalona, Rady J. Laborde, Carlos Alvarez, Luis E. Fernández, Michael N. Starnbach, Darren E. Higgins, María E. Lanio   +11 more
doaj   +1 more source

Azacarbazole n-3 and n-6 polyunsaturated fatty acids ethyl esters nanoemulsion with enhanced efficacy against Plasmodium falciparum

Bioactive Materials, 2021
Alternative therapies are necessary for the treatment of malaria due to emerging drug resistance. However, many promising antimalarial compounds have poor water solubility and suffer from the lack of suitable delivery systems, which seriously limits ...
Anna Jaromin, Silvia Parapini, Nicoletta Basilico, Magdalena Zaremba-Czogalla, Agnieszka Lewińska, Agnieszka Zagórska, Maria Walczak, Bożena Tyliszczak, Aleksandra Grzeszczak, Marcin Łukaszewicz, Łukasz Kaczmarek, Jerzy Gubernator   +11 more
doaj  

Enhanced active targeting via cooperative binding of ligands on liposomes to target receptors. [PDF]

PLoS ONE, 2013
To achieve effective active targeting in a drug delivery system, we previously developed dual-targeting (DT) liposomes decorated with both vascular endothelial growth factor receptor-1 (VEGFR-1)-targeted APRPG and CD13-targeted GNGRG peptide ligands for ...
Tomoki Sugiyama, Tomohiro Asai, Yuki Murase Nedachi, Yasufumi Katanasaka, Kosuke Shimizu, Noriyuki Maeda, Naoto Oku   +6 more
doaj   +1 more source

Camptothecin-Loaded Liposomes with α-Melanocyte-Stimulating Hormone Enhance Cytotoxicity Toward and Cellular Uptake by Melanomas: An Application of Nanomedicine on Natural Product

Journal of Traditional and Complementary Medicine, 2013
In this study, we attempted to develop functional liposomes loaded with camptothecin and attached to α-melanocyte-stimulating hormone (α-MSH) to target melanoma cells.
Chih-Hung Lin, Saleh A. Al-Suwayeh, Chih-Feng Hung, Chih-Chieh Chen, Jia-You Fang   +4 more
doaj   +1 more source

Perspectives for New and More Efficient Multifunctional Ligands for Alzheimer′s Disease Therapy

Molecules, 2020
Despite tremendous research efforts at every level, globally, there is still a lack of effective drugs for the treatment of Alzheimer′s disease (AD). The biochemical mechanisms of this devastating neurodegenerative disease are not yet clearly understood.
Agnieszka Zagórska, Anna Jaromin
doaj   +1 more source

Synthetic phospholipid vesicles containing a purified viral antigen and cell membrane proteins stimulate the development of cytotoxic T lymphocytes [PDF]

, 1979
Synthetic phospholipid vesicles (liposomes) containing the purified glycoprotein (G) of vesicular stomatitis virus (VSV) and solubilized membrane proteins from cells of the appropriate H-2 haplotype elicited H-2-restricted cytotoxic T lymphocytes (CTL ...
Baltimore, David, Eisen, Herman N., Hale, Arthur H., Loh, Dennis, Ross, Alonzo H.   +4 more
core   +1 more source