Results 201 to 210 of about 28,679 (286)

Targeting LRH-1 alleviates diabetes-induced lipotoxicity in podocytes: role of PLIN5-mediated lipid droplet turnover. [PDF]

Ren Fail
Guan Q, Zhu Z, Hu H, Wang J, Fan Y, Ye P, Yang Q, Ding G, Hu J.   +8 more
europepmc   +1 more source

Maternal Intake of Dipteryx alata Vog. Reduces Offspring's Brain Oxidative Stress and Anxiety: Insights From In Silico and In Vivo Studies

Journal of Food Science, Volume 91, Issue 6, June 2026.
ABSTRACT We undertook a computational investigation and evaluation of the impact of maternal supplementation with baru almonds (Dipteryx alata Vog.) on anxiety‐like behavior and oxidative stress in the brains of adolescent and adult rat offspring. Molecular docking studies were conducted and revealed that the phenolic compounds (PCs) from the baru ...
Diego Elias Pereira, Rita de Cássia de Araújo Bidô, Maciel da Costa Alves, Renally de Lima Moura, Ana Carolina dos Santos Costa, Larissa Maria Gomes Dutra, Louis Gustavo da Costa Sobral e Sá, Vanessa Bordin Viera, Jaqueline Ferreira Ramos, Juliano Carlo Rufino Freitas, Daline Fernandes de Araújo, Gerlane Coelho Bernardo Guerra, Juliana Késsia Barbosa Soares   +12 more
wiley   +1 more source

Dysregulation of the AMPK-SREBP1-FASN axis in MASLD: driving a vicious cycle of lipotoxicity and metabolic-immune crosstalk. [PDF]

Lipids Health Dis
Zhao Q, Lu S, Guan Y, Sun Z, Qiu S, Zhang A.   +5 more
europepmc   +1 more source

‘Lipotoxic cardiomyopathy’: A suspected case of lipotoxic infiltration of the myocardium

Indian Journal of Cardiology
Tanuj Bhatia, Vanshaj Sharma, Anamika Gupta, Devendra Bisth, Kunal Mahajan   +4 more
openaire   +1 more source

Beyond GLP‐1: The Cardiometabolic Potential of Dual GLP‐1/GIP Receptor Agonists

iNew Medicine, Volume 2, Issue 2, June 2026.
Chao Xue
wiley   +1 more source

Magnesium as a Bioenergetic Checkpoint Linking Mitochondrial Function, Metabolic Disease, and Aging

Aging Cell, Volume 25, Issue 6, June 2026.
This review positions magnesium as a central bioenergetic checkpoint that orchestrates mitochondrial function and metabolic resilience. By defining the functional ATP pool and stabilizing mitochondrial performance, magnesium homeostasis serves as a mechanistic link between renal handling, metabolic disease, and the aging process.
Chien‐Wei Huang, Chen‐Yueh Wen, Andy P. Tsai, Boyang Wang, Kuan‐Hao Tsui, Yu‐Juei Hsu, Chia‐Jung Li   +6 more
wiley   +1 more source

Peripheral metabolic-redox signaling as a core mechanism of major depressive disorder: evidence from deep metabolomic phenotyping. [PDF]

Acta Neuropsychiatr
Maes M, Niu M, Maes A, Luo Y, Yangyang C, Almulla AF, Li J, Zhang Y.   +7 more
europepmc   +1 more source

Sphingosine‐1‐Phosphate Promotes FOS Activation in Osteosarcoma Under Tumor Acidosis

Acta Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aim The tumor microenvironment in solid tumors is characterized by extracellular acidosis, which promotes cancer aggressiveness. In osteosarcoma, the most common primary bone cancer, a highly acidic tumor microenvironment is associated with metastasis and poor prognosis, partly due to metabolic rewiring, including changes in lipid pathways ...
Nicolò Bozzini, Margherita Cortini, Alberto Righi, Agamemnon E. Grigoriadis, Michael Dack, Elizabeta Ilieva, Federica Torricelli, Veronica Manicardi, Nicola Baldini, Sofia Avnet   +9 more
wiley   +1 more source

Gypenoside XLIX and Mitochondria-Associated ER Membranes in Non-Alcoholic Fatty Liver Disease: Mechanistic Insights and Emerging Perspectives. [PDF]

Molecules
Kwan X, Aslam MS, Liang H, Chen S.
europepmc   +1 more source

Cannabidiol and cannabigerol ameliorate steatotic liver disease via phosphocreatine buffering and lysosomal restoration

British Journal of Pharmacology, Volume 183, Issue 12, Page 3173-3194, June 2026.
Cannabidiol (CBD) and cannabigerol (CBG) alleviate hepatic steatosis in obese mice by shifting energy buffering towards phosphocreatine and enhancing lysosomal lipid degradation and trafficking. These effects are associated with increased creatine kinase activity and lysobisphosphatidic acid (LBPA) levels, highlighting a previously unrecognised ...
Radka Kočvarová, Shahar Azar, Bella Agranovich, Ifat Abramovich, Saveliy Kirillov, Alina Nemirovski, Saja Baraghithy, Inbar Plaschkes, Emmanuelle Merquiol, Alexander Rouvinski, Galia Blum, Liad Hinden, Joseph Tam   +12 more
wiley   +1 more source