Results 211 to 220 of about 28,679 (286)
Lipid droplets beyond storage: Cellular metabolic modulator in the diabetic heart (Review). [PDF]
Liang Y +12 more
europepmc +1 more source
Neurological disorders are hard to treat. Stem cell‐derived neural organoids enable research, and their transplantation aids CNS therapy, with this article reviewing relevant advances, challenges and prospects. ABSTRACT Neurological disorders are often devastating and notoriously difficult to repair, creating an urgent need for novel research models ...
Yutong Wang +8 more
wiley +1 more source
Lipid metabolism-inflammation crosstalk and risk of incident cancer, cardiovascular diseases, and stroke among individuals with prediabetes: findings from a nationwide, population based, prospective cohort study. [PDF]
Li W, Chen J, Fu Y, Wang W, Zeng Q.
europepmc +1 more source
Mitochondrial Dysfunction at the Intersection of CKM Syndrome: Molecular Mechanisms and Path-to-Target Therapies. [PDF]
Kuo YJ +4 more
europepmc +1 more source
ABSTRACT Background/Aims Metabolic bariatric surgery remains the most potent weapon we have against severe obesity and its metabolic consequences. Yet, its effects on the liver are far from uniform. Although restrictive and mixed procedures like sleeve gastrectomy and Roux‐en‐Y gastric bypass consistently improve metabolic dysfunction‐associated ...
Francesco Saverio Papadia +3 more
wiley +1 more source
Lipotoxicity in Diabetic Cardiomyopathy: Molecular Basis and Emerging Therapeutic Targets. [PDF]
Han Y, Chen X, Fonseka O, Liu W.
europepmc +1 more source
Intra‐tumoral oxygen deprivation (hypoxia) promotes the activation of hypoxia‐inducible factors (HIFs) that orchestrate the transcriptional adaptation of cancer cells to hypoxia. Hypoxia is prevalent in hepatocellular carcinoma (HCC), a cancer type with limited therapeutic options.
Ioanna‐Maria Gkotinakou +6 more
wiley +1 more source
Molecular and cellular mechanisms of muscle-adipose tissue crosstalk driving sarcopenic obesity: an integrative review of human, animal, and in vitro models. [PDF]
Seliem MA, Ragab MA.
europepmc +1 more source
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, with an increasing number of patients progressing to cirrhosis and hepatocellular carcinoma (HCC). Early identification of individuals at high risk for advanced fibrosis is essential for preventing liver‐related ...
Norio Akuta +44 more
wiley +1 more source

