Results 91 to 100 of about 11,031 (247)

Aspirin-triggered lipoxin A4 attenuates LPS-induced pro-inflammatory responses by inhibiting activation of NF-κB and MAPKs in BV-2 microglial cells [PDF]

, 2011
Background Microglial activation plays an important role in neurodegenerative diseases through production of nitric oxide (NO) and several pro-inflammatory cytokines.
Yan-Ping Wang, Yan Wu, Long-Yan Li, Jin Zheng, Ren-Gang Liu, Jie-Ping Zhou, Shi-Ying Yuan, You Shang, Shang-Long Yao   +8 more
core   +2 more sources

Histiocytes: Multifaceted Regulators of Health and Disease

Veterinary Clinical Pathology, EarlyView.
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley   +1 more source

15-HETE is the main eicosanoid present in mucus of ulcerative protocolitis [PDF]

, 1991
Prostaglandins, leukotrienes and mono-hydroxy acid products of arachidonic acid were measured in mucus of freshly recovered morning stools of a patient with an exacerbation of ulcerative proctocolitis. Eicosanoids in ether extracts were separated by high
Wilson, J.H.P. (Paul), Zijlstra, F.J. (Freek)   +1 more
core   +2 more sources

Restoration of Gut Microbiota and Metabolic Homeostasis by Lacticaseibacillus paracasei Zhang in Azithromycin‐Induced Dysbiosis

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
This study investigated whether Lacticaseibacillus paracasei Zhang could alleviate the gut microbiota imbalance and its systemic consequences caused by antibiotics. Mice treated with azithromycin exhibited gut microbiota disorders, and subsequent probiotic intervention was carried out.
Xiaoye Liu, Guoqiang Yao, Temuujin Bayarjargal, Lai‐Yu Kwok, Wenyi Zhang   +4 more
wiley   +1 more source

Supplementary Figure S5 from NAP1051, a Lipoxin A4 Biomimetic Analogue, Demonstrates Antitumor Activity Against the Tumor Microenvironment

, 2023
Tiange Dong, Priyal Dave, EunJeong Yoo, Brandon Ebright, Kabir Ahluwalia, Eugene Zhou, Isaac Asante, Malika Salimova, H. Pei, Tracey Lin, Andrew Mead, Zeyang Li, Mark S. Humayun, Nicos A. Petasis, Alan L. Epstein, Stan G. Louie   +15 more
openalex   +2 more sources

Lung Injury Prevention with Aspirin (LIPS-A): a Protocol for a Multicentre Randomised Clinical Trial in Medical Patients at High Risk of Acute Lung Injury [PDF]

, 2012
Introduction: Acute lung injury (ALI) is a devastating condition that places a heavy burden on public health resources. Although the need for effective ALI prevention strategies is increasingly recognised, no effective preventative strategies exist.
Banner-Goodspeed, Valerie M, Carter, Rickey E, Gajic, Ognjen, Gong, Michelle Ng, Hinds, Richard, Kor, Daryl Jon, Park, Pauline K, Talmor, Daniel   +7 more
core   +1 more source

Lipid Metabolism and Obesity in Early Life: Drivers of Chronic Lung Disease From Development to Adulthood

Molecular Nutrition &Food Research, Volume 70, Issue 7, 15 April 2026.
Metabolic and nutritional stressors are a growing global health concern. This review discusses how obesity, lipids, and lipid derivatives influence lung development, homeostasis, and chronic lung disease progression, highlighting roles of alveolar surfactant and sphingolipids.
Jaco Selle, Natascha Mierswa, Leon Saschin, Jana Niehues, Jörg Dötsch, Eva Nüsken, Kai‐Dietrich Nüsken, Julia Schipke, Miguel A. Alejandre Alcazar   +8 more
wiley   +1 more source

In Vitro Modeling of Age‐Associated Lipid Mediator's Impact on Vascular Biology Following Platelet Concentrate Transfusion

Aging Cell, Volume 25, Issue 4, April 2026.
Age‐associated LPA affects adverse reactions and alters platelet and endothelial biology following platelet concentrate transfusion. Age‐associated LPC, S1P could be involved in adverse reactions, in platelet and endothelium biology following a PC transfusion.
Amelie Prier, Mailys Portier, Chloe Heranney, Nancy Kouadio, Charles‐Antoine Arthaud, Marie‐Ange Eyraud, Marco Heestermans, Justine Bertrand‐Michel, Hind Hamzeh‐Cognasse, Fabrice Cognasse, Anne‐Claire Duchez   +10 more
wiley   +1 more source

Distinguishing Features of ILC2s During Type 2 Immune Responses

European Journal of Immunology, Volume 56, Issue 2, February 2026.
Group 2 innate lymphoid cells (ILC2s) are tissue‐resident cells regulated by diverse signals often emanating from surrounding nonhematopoietic cells at barrier surfaces. Their effector cytokines determine tissue homeostasis at steady state and during type 2 immunity in allergies or worm infections.
Manuel O. Jakob, Patrycja M. Forster, Christoph S. N. Klose   +2 more
wiley   +1 more source

A defect in Δ⁶ and Δ⁵ desaturases may be a factor in the initiation and progression of insulin resistance, the metabolic syndrome and ischemic heart disease in South Asians

Lipids in Health and Disease, 2010
The high incidence of insulin resistance and the metabolic syndrome in South Asians remains unexplained. I propose that a defect in the activity of Δ6 and Δ5 desaturases and consequent low plasma and tissue concentrations of polyunsaturated fatty acids ...
Das Undurti N
doaj   +1 more source