Results 91 to 100 of about 112,955 (338)
Molecules, 2018 The basal production of secondary metabolites in medicinal plants is limited. One of the effective approaches that encourages plants to produce a remarkable amount of precious compounds is an application of elicitors.
Andrea Balažová +6 more
doaj +1 more source
Genome-wide identification and expression analysis of lipoxygenase genes in Tartary buckwheat
Biotechnology & Biotechnological Equipment, 2020 Lipoxygenases (LOXs; EC1.13.11.12) are widely involved in plant growth, development, maturation, senescence and stress resistance. LOXs have been studied in many crop species but not in Tartary buckwheat [Fagopyrum tataricum (L.) Gaertn.].
Qiqi Ji +4 more
doaj +1 more source
Plant lipoxygenase: structure and mechanism [PDF]
, 2015 in: Portland Press research monograph XI, (issn: 0964-5845)/ A.F. Rowley, H. Kuhn and T. Schewe (eds.)
Vliegenthart, J.F.G. +3 more
openaire +2 more sources
Phase 2 trial of montelukast for prevention of pain in sickle cell disease. [PDF]
, 2020 Cysteinyl leukotrienes (CysLTs) are lipid mediators of inflammation. In patients with sickle cell disease (SCD), levels of CysLTs are increased compared with controls and associated with a higher rate of hospitalization for pain. We tested the hypothesis
Brandow, Amanda +9 more
core
Tertiary alkylamines as nucleophiles in substitution reactions at heteroaromatic halide during the synthesis of the highly potent pirinixic acid derivative 2-(4-chloro-6-(2,3-dimethylphenylamino)pyrimidin-2-ylthio)octanoic acid (YS-121) [PDF]
, 2011 YS-121 [2-(4-chloro-6-(2,3-dimethylphenylamino)pyrimidin-2-ylthio)octanoic acid] is the result of target-oriented structural derivatization of pirinixic acid.
Gabler, Matthias +1 more
core +2 more sources
Journal of Chemical Technology &Biotechnology, EarlyView.Abstract BACKGROUND Selecting an optimal chromatography resin during biopharmaceutical downstream process development is a great challenge. This is especially the case for recombinant subunit vaccines, where product properties vary greatly and recovery often involves cell lysis, which yields a complex mixture of different host cell materials. Host cell
Tim Neijenhuis +4 more
wiley +1 more source
Molecules, 2018 A new series of 2,4,6-trihydroxy-3-geranyl-acetophenone (tHGA) analogues were synthesized and evaluated for their lipoxygenase (LOX) inhibitory activity. Prenylated analogues 4a–g (half maximal inhibitory concentration (IC50) values ranging from 35
Chean Hui Ng +6 more
doaj +1 more source
Methyl jasmonate and cis jasmone induce apoptosis in Pc-3 and LncaP prostate cancer lines
, 2005 Methyl jasmonate (MJ) and cis jasmone (CJ), lipid-derived plant stress hormones, were studied for their effects against both hormone dependent (LNCaP) and hormone independent (PC3) human prostate cancer cell lines. Both 2 mM MJ or CJ inhibited the growth
Bathina, Madhavi
core +1 more source
ATP allosterically activates the human 5-lipoxygenase molecular mechanism of arachidonic acid and 5(S)-hydroperoxy-6(E),8(Z),11(Z),14(Z)-eicosatetraenoic acid. [PDF]
, 2014 5-Lipoxygenase (5-LOX) reacts with arachidonic acid (AA) to first generate 5(S)-hydroperoxy-6(E),8(Z),11(Z),14(Z)-eicosatetraenoic acid [5(S)-HpETE] and then an epoxide from 5(S)-HpETE to form leukotriene A4, from a single polyunsaturated fatty acid ...
Barbour, Shannon R +4 more
core +2 more sources
JSFA reports, EarlyView.Abstract Background Inadequate nutrition is a leading factor in global health challenges, particularly in sub‐Saharan Africa, where malnutrition and hunger remain widespread. Fig‐leaf gourd (Cucurbita ficifolia), a nutrient‐dense African leafy vegetable, is readily available to low‐income populations and holds promise for improving micronutrient intake
J. M. Gachoya +2 more
wiley +1 more source