Results 131 to 140 of about 43,549 (263)

1H NMR metabolomics and lipidomics analysis of neutrophils reveals biomarkers of ageing, inflammageing and frailty

open access: yesThe FEBS Journal, EarlyView.
Using 1H NMR metabolomics, we measured polar and lipid metabolites from human blood neutrophils from people with frailty (n = 31, mean age 84Y), people with rheumatoid arthritis (n = 16, mean age 55Y), robust older (n = 24, mean age 66Y) and healthy younger people (n = 21, mean age 22Y).
Genna Ali Abdullah   +5 more
wiley   +1 more source

ALOX15 mediates thrombin‐induced myristoylation, trafficking, and interaction of protease‐activated receptors, leading to platelet activation and hemostasis

open access: yesThe FEBS Journal, EarlyView.
The role of PARs in platelet function is fairly known; however, the underlying mechanisms are not fully understood. We report that thrombin myristoylates PAR4 in mouse platelets and PAR1 and PAR4 in human platelets, facilitating their membrane transport and interaction, leading to PAR3/4 heterodimers in mice and PAR1/4 heterodimers in humans.
Suresh Govatati   +4 more
wiley   +1 more source

Natural‐based antioxidants in cosmeceuticals: Extraction, bioavailability and skin ageing applications

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Natural antioxidants from plants, fruits, seeds and fungi combat ageing by neutralizing free radicals, boosting collagen and protecting against UV damage. Enhanced by green extraction and smart delivery systems, they offer powerful anti‐inflammatory and antimicrobial benefits.
Hossein Omidian   +2 more
wiley   +1 more source

A century of vitamin E research: The innovative journey from basic biology to synthetic bio‐manufacturing

open access: yesJournal of Integrative Plant Biology, EarlyView.
For a century, Vitamin E has been studied for its health benefits. This review traces its journey from basic biological discovery, and the recent identification of its link to chlorophyll degradation, to the modern era of sustainable microbial manufacturing, highlighting the innovative technologies that define its future production.
Ruiqi Zhang   +7 more
wiley   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

open access: yesJournal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima   +3 more
wiley   +1 more source

Pharmacokinetics and Anti‐Inflammatory Effects of Intramuscular Betamethasone in Exercised Thoroughbred Horses

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The pharmacokinetics and pharmacodynamics of betamethasone following intra‐articular administration to horses have been described; however, studies characterizing intramuscular administration are lacking. Twenty‐four horses received an intramuscular dose of 12 mg betamethasone sodium phosphate/betamethasone acetate.
Juliana Sullivan   +4 more
wiley   +1 more source

Screening of Organisms Producing Inhibitors of 15-Lipoxygenase Among Micromycetes

open access: yesАнтибиотики и Химиотерапия, 2020
The effects of extracts from the mycelium of Lecanicilium lecanii No.169, Beauveria fellina No.7 and Beauveria bassiana No.15 on the activity of 15-lipoxygenase (15-LO) recovered from rat reticulocytes was investigated.
M. V. Bibikova   +6 more
doaj  

A Hierarchical VvbHLH30‐VvERF70‐VvACS2 Module Orchestrates Ethylene Biosynthesis and Cold Adaptation in Grapevine

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Ethylene is a key gaseous phytohormone that plays crucial roles in regulating plant growth, development and stress responses. However, ethylene‐associated biosynthetic and transcriptional regulatory mechanisms governing cold‐adaptation responses in plants remain poorly understood.
Yujun Hou   +12 more
wiley   +1 more source

Design, synthesis, and SAR study of isopropoxy allylbenzene derivatives as 15-lipoxygenase inhibitors. [PDF]

open access: yesIran J Basic Med Sci, 2020
Mousavian M   +5 more
europepmc   +1 more source

CRISPR/Cas‐Mediated Gene Editing in Plant Immunity and Its Potential for the Future Development of Fungal, Oomycete, and Bacterial Pathogen‐Resistant Pulse Crops

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Pulses provide myriad health benefits and are advantageous in an environmental context as a result of their leguminous nature. However, phytopathogenic fungi, oomycetes and bacteria pose a substantial threat to pulse production, at times leading to crop failure.
Stacy D. Singer   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy