Results 41 to 50 of about 4,273 (194)
Apicoplast lipoic acid protein ligase B is not essential for Plasmodium falciparum.
PLoS Pathogens, 2007 Lipoic acid (LA) is an essential cofactor of alpha-keto acid dehydrogenase complexes (KADHs) and the glycine cleavage system. In Plasmodium, LA is attached to the KADHs by organelle-specific lipoylation pathways.
Svenja Günther +8 more
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Flashy flagella: flagellin modification is relatively common and highly versatile among the Enterobacteriaceae [PDF]
, 2016 Schematic diagrams of inserts within the fliDCAZ loci of FGI−/FMI− Enterobacteriaceae. Flanking genes are indicated by yellow arrows, predicted phage genes by blue arrows, fimbrial biogenesis genes by grey arrows and sugar/amino acid transporter genes by
Don A. Cowan, Pieter De Maayer
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LipoFNT: Lipoylation Sites Identification with Flexible Neural Tree
Complexity, 2019 Lysine lipoylation is a special type of posttranslational modification in both prokaryotes’ and eukaryotes’ proteomics researches. Such a modification takes part in several significant biological processions and plays a key role in the cellular level. In
Wenzheng Bao +3 more
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Targeted next generation sequencing in patients with inborn errors of metabolism [PDF]
, 2018 BACKGROUND: Next-generation sequencing (NGS) technology has allowed the promotion of genetic diagnosis and are becoming increasingly inexpensive and faster.
Armstrong i Morón, Judith +9 more
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Nature Communications, 2023 Methionine restriction (MR) provides metabolic benefits in many organisms. However, mechanisms underlying the MR-induced effect remain incompletely understood. Here, we show in the budding yeast S.
Wen Fang +8 more
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Library of Apicomplexan Metabolic Pathways: a manually curated database for metabolic pathways of apicomplexan parasites. [PDF]
, 2012 The Library of Apicomplexan Metabolic Pathways (LAMP, http://www.llamp.net) is a web database that provides near complete mapping from genes to the central metabolic functions for some of the prominent intracellular parasites of the phylum Apicomplexa ...
Gonzalez-Galarza, FF +4 more
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Journal of Biological Chemistry, 1966 Abstract The sensitivity of lipoyl dehydrogenase to phenylmercuric acetate, a reagent for —SH groups, has been investigated. Titration of available sulfhydryl groups in the enzyme brings about inactivation in the reduced diphosphopyridine nucleotide-lipoyl reductase activity, while activity with the artificial hydrogen acceptor 2,6-dichloroindophenol ...
L, Casola, V, Massey
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Ferroptosis inducers enhanced cuproptosis induced by copper ionophores in primary liver cancer
Journal of Experimental & Clinical Cancer Research, 2023 Introduction Cuproptosis and ferroptosis are the two newly defined metal-related regulated cell death. However, the crosstalk between cuproptosis and ferroptosis is obscure.
Weikai Wang +7 more
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Crystallographic snapshots of sulfur insertion by lipoyl synthase [PDF]
Proceedings of the National Academy of Sciences, 2016 Significance Lipoic acid, an enzyme cofactor in central metabolism and a livestock feed supplement, is produced on an industrial scale by a costly multistep synthesis. Nature makes lipoic acid in one step by the chemically challenging addition of two sulfur atoms to an inert fatty acid chain.
Lanz, Nicholas D. +5 more
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Sirtuin Lipoamidase Activity Is Conserved in Bacteria as a Regulator of Metabolic Enzyme Complexes
mBio, 2017 Lipoic acid is an essential metabolic cofactor added as a posttranslational modification on several multimeric enzyme complexes. These protein complexes, evolutionarily conserved from bacteria to humans, are core regulators of cellular metabolism.
Elizabeth A. Rowland +5 more
doaj +1 more source