Results 81 to 90 of about 6,017,039 (234)
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Evaluation of Electro-Optic Behaviour of Chiral Smetic Liquid Crystals Dispalys with V-shaped response [PDF]
, 2003 In the last years, chiral smectic liquid crystals with V-shaped electro-optic response have been reported as one of the most promising technologies for display applications.
Urruchi del Pozo, Virginia +3 more
core +2 more sources
Driving Forces of Liquid–Liquid Phase Separation in Biological Systems
Biomolecules, 2019 Analysis of liquid−liquid phase separation in biological systems shows that this process is similar to the phase separation observed in aqueous two-phase systems formed by nonionic polymers, proteins, and polysaccharides.
Boris Y. Zaslavsky +2 more
doaj +1 more source
Separation of p-Nitrophenol and o-Nitrophenol with three-liquid-phase extraction system
, 2009 Three-liquid-phase systems containing polyethylene glycol with different molecular weight were explored to investigate the partitioning behavior of simulated wastewater-containing isomers of p-Nitrophenol (p-NP) and o-Nitrophenot (o-NP). The distribution
Yu, Pinhua +7 more
core +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Liquid–liquid phase separation of LARP7 restrains HIV-1 replication
EMBO ReportsHIV-1 initiates replication by its transactivator Tat, hijacking the positive transcription elongation factor b (P-TEFb) in the host cell. Most P-TEFb is maintained in an inactive state by 7SK snRNP until it is brought to the transcription initiation ...
Zhuoxin Li +18 more
doaj +1 more source
Voltage programmable liquid optical devices [PDF]
, 2009 In this study I have looked at two types of voltage programmable liquid optical device. The first is a rotatable liquid crystal waveplate and the second is an amplitude programmable liquid phase grating. The rotatable waveplate was created by confining a
Wells, GG, Wells, Gary George
core
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Molecular Dynamics Simulation of Binary liquid mixture Phase Separation and Glass Transition
Chemical Engineering Transactions, 2018 This paper aims to study the phase separation of binary liquid mixture and two-phase glass transition process by using the method of molecular dynamics (MD) simulation.
Meili Li, Xingye Fu
doaj +1 more source