Results 91 to 100 of about 113,588 (316)

Application of Sequencing, Liquid Biopsies, and Patient-Derived Xenografts for Personalized Medicine in Melanoma [PDF]

, 2015
María Romina Girotti, Gabriela Gremel, Rebecca Lee, Elena Galvani, Dominic G. Rothwell, Amaya Virós, Amit Kumar Mandal, Kok Haw Jonathan Lim, Grazia Saturno, Simon J. Furney, Franziska Baenke, Malin Pedersen, Jane Rogan, Jacqueline Swan, Matthew Ryan Smith, Alberto Fusi, Deemesh Oudit, Nathalie Dhomen, Ged Brady, Paul Lorigan, Caroline Dive, Richard Marais   +21 more
openalex   +1 more source

Crosstalk of non-apoptotic RCD panel in hepatocellular carcinoma reveals the prognostic and therapeutic optimization

iScience
Summary: Non-apoptotic regulated cell death (RCD) of tumor cells profoundly affects tumor progression and plays critical roles in determining response to immune checkpoint inhibitors (ICIs). Prognosis-distinctive HCC subtypes were identified by consensus
Shuo Li, Yaqi Xu, Xin Hu, Hao Chen, Xiaodan Xi, Fei Long, Yuan Rong, Jun Wang, Chunhui Yuan, Chen Liang, Fubing Wang   +10 more
doaj   +1 more source

Liquid biopsy - a review

Journal of Education, Health and Sport
Introduction and objective:Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths worldwide. Early detection is crucial for better outcomes. Traditional diagnostic methods, such as imaging and biopsies, often fail to detect HCC in early stages.
Weronika Rutkowska-Kawalec, Karolina Michalczuk, Dariusz Fabian, Marek Kurowski, Elżbieta Leszczyńska-Knaga, Natalia Jakubczyk, Paweł Moczydłowski, Monika Ryglewicz, Anna Gliwa, Karolina Kuczapska   +9 more
openaire   +2 more sources

Fabrication of Patterned Composite Microneedles via Inkjet Printing for Enhanced Drug Delivery

Advanced Healthcare Materials, EarlyView.
A novel inkjet printing‐based microneedle platform enabling multi‐material fabrication for customizable and scalable transdermal drug delivery. Abstract Microneedle (MN) technology offers a minimally invasive, patient‐friendly alternative to conventional hypodermic injections for dermal drug delivery.
Sanghyeok Jang, Jooyoung Lee, Hyungseok Lee   +2 more
wiley   +1 more source

Challenges for CTC-based liquid biopsies: low CTC frequency and diagnostic leukapheresis as a potential solution [PDF]

, 2015
Nikolas H. Stoecklein, Johannes Fischer, Dieter Niederacher, Leon W.M.M. Terstappen   +3 more
openalex   +1 more source

Ascorbic Acid Modulates Collagen Properties in Glucocorticoid‐Induced Osteoporotic Bone: Insights into Chemical, Mechanical, and Biological Regulation

Advanced Healthcare Materials, EarlyView.
Osteoporosis from long‐term glucocorticoid (GIOP) use elevates susceptibility to fracture. This study shows GCs impair ascorbic acid (AA) metabolism in osteoblasts, collagen synthesis and extracellular matrix integrity. AA enhanced collagen biochemical and mechanical properties and restored osteoblast and endothelial function. These findings underscore
Micaila DE Curtis, Yoontae Kim, Rahul Patil, Xinran Zhang, Meth Jayatilake, Orelle Bulgin, Peter Lialios, Sana Surrency, Soraya Tarrah, Argyris K. Lazaris, Alison Grafton, James Williams IV, Seyedeh Boshra Nouraie, Maria Bizaki, Penelope Xeron, Edward Van Keuren, Jonathan E. Seppala, Evagelia C. Laiakis, Joanna B. Kitlinska, Stella Alimperti   +19 more
wiley   +1 more source

A liquid biopsy for head and neck cancers [PDF]

, 2015
Henri Schmidt, Arutha Kulasinghe, Chris Perry, Colleen C. Nelson, Chamindie Punyadeera   +4 more
openalex   +1 more source

Injectable Dual‐Crosslinked Poly(oligo(Ethylene Glycol) Methacrylate) Hydrogels Inspired by Mussel Adhesion for Cutaneous Wound Healing and Functional Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
Injectable POEGMA‐DA hydrogels, dual‐crosslinked via dopamine self‐polymerization and dynamic hydrazone bonds, provide a safer alternative to invasive wound closure methods and toxic bioadhesives. Mimicking skin‐like mechanics, they achieve effective tissue adhesion for acute dermal wounds, supporting improved healing outcomes, including reducing ...
Gurpreet Kaur Randhawa, Meghan Kostashuk, Zhicheng Pan, Nils Nordstrom, Thomas Kalab, Erica Winterhelt, Todd Hoare   +6 more
wiley   +1 more source

Growth Hormone‐Loaded 3D Printed Silk Fibroin‐Cellulose Dressings for Ischemic Wounds

Advanced Healthcare Materials, EarlyView.
3D‐printed wound dressings combining carboxymethyl cellulose, silk fibroin, and growth hormone accelerate healing in diabetic ulcers. These bioactive, customizable dressings enhance angiogenesis, cellular proliferation, and immune modulation. Proteomic analysis reveals activation of regenerative pathways and reduced fibrosis, highlighting their ...
Maria Pita‐Vilar, Diego Caicedo‐Valdés, Susana B. Bravo, Isabel Rodriguez‐Moldes, Salvador D. Aznar‐Cervantes, Angel Concheiro, Carmen Alvarez‐Lorenzo, Luis Diaz‐Gomez   +7 more
wiley   +1 more source

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao, Chandan Kumar Mandal, Fernando Patolsky   +2 more
wiley   +1 more source