Results 91 to 100 of about 3,006,723 (410)

Liquid biopsy: from concept to clinical application

Scientific Reports, 2023
The diagnosis and treatment of cancer presents a physical and mental burden to the patient, often involving diagnostic biopsies and surgeries or chemotherapeutic approaches with severe side-effects.
C. Alix-Panabières, Dario Marchetti, Julie E. Lang   +2 more
semanticscholar   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

The Impact of Steatosis on Chronic Hepatitis C Progression and Response to Antiviral Treatments

Biomedicines, 2021
Metabolic derangement is characteristic in patients with hepatitis C virus (HCV) infection. Aside from established liver injury, various extrahepatic metabolic disorders impact the natural history of the disease, clinical outcomes, and the efficacy of ...
Phumelele Yvonne Siphepho, Yi-Ting Liu, Ciniso Sylvester Shabangu, Jee-Fu Huang, Chung-Feng Huang, Ming-Lun Yeh, Ming-Lung Yu, Shu-Chi Wang   +7 more
doaj   +1 more source

Beyond blood: Advancing the frontiers of liquid biopsy in oncology and personalized medicine

Cancer Science
Liquid biopsy is emerging as a pivotal tool in precision oncology, offering a noninvasive and comprehensive approach to cancer diagnostics and management.
Ying Bao, Dejing Zhang, Huihui Guo, Wenxue Ma   +3 more
semanticscholar   +1 more source

Liquid biopsy in lung cancer: significance in diagnostics, prediction, and treatment monitoring

Molecular Cancer, 2022
Primary lung cancer is one of the most common malignant tumors in China. Approximately 60% of lung cancer patients have distant metastasis at the initial diagnosis, so it is necessary to find new tumor markers for early diagnosis and individualized ...
Wen Li, Jibin Liu, L. Hou, Fei Yu, J. Zhang, Wei Wu, Xiao Tang, Feng Sun, Hai-Min Lu, Jing Deng, Jie Bai, Juan Li, Chun-yan Wu, Qin-Lu Lin, Zhongdong Lv, Gao-Ren Wang, Geng-Xi Jiang, Yu-Shui Ma, Da Fu   +18 more
semanticscholar   +1 more source

Liquid biopsies in cancer

Molecular Biomedicine
Abstract Cancer ranks among the most lethal diseases worldwide. Tissue biopsy is currently the primary method for the diagnosis and biological analysis of various solid tumors. However, this method has some disadvantages related to insufficient tissue specimen collection and intratumoral heterogeneity.
Hang Yin, Manjie Zhang, Yu Zhang, Xuebing Zhang, Xia Zhang, Bin Zhang   +5 more
openaire   +3 more sources

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

The potential of hydrogel‐free tumoroids in head and neck squamous cell carcinoma

Cancer Medicine
Background Head and neck malignancy, and in particular squamous cell carcinoma (SCC), is responsible for a significant disease burden globally. The lack of an optimal in vitro model system to accurately recapitulate in vivo response to therapy in HNSCC ...
Michael Wong, Sarju Vasani, Omar Breik, Xi Zhang, Lizbeth Kenny, Chamindie Punyadeera   +5 more
doaj   +1 more source

Liquid biopsies in lung cancer: The new ambrosia of researchers [PDF]

, 2014
In the last decades the approach to cancer patient management has been deeply revolutionized. We are moving from a "one-fits-all" strategy to the "personalized medicine" based on the molecular characterization of the tumor. In this new era it is becoming
ALESSANDRO, Riccardo, Baggerman, G, Carreca, AP, CASTIGLIA, Marta, Gil Bazo, I, Hong, D, Mertens, I, PASSIGLIA, Francesco, Pauwels, P., Peeters, M, Rolfo, C, RUSSO, Antonio, TAVERNA, Simona, VENTO, Renza, Zwaenepoel, K   +14 more
core   +1 more source

Liquid biopsy techniques and lung cancer: diagnosis, monitoring and evaluation

Journal of experimental & clinical cancer research : CR
Lung cancer stands as the most prevalent form of cancer globally, posing a significant threat to human well-being. Due to the lack of effective and accurate early diagnostic methods, many patients are diagnosed with advanced lung cancer.
Fei Ren, Qian Fei, Kun Qiu, Yuanjie Zhang, Heyang Zhang, Lei Sun   +5 more
semanticscholar   +1 more source