Results 61 to 70 of about 3,770 (149)

Anti-Inflammatory Activities of Licorice Extract and Its Active Compounds, Glycyrrhizic Acid, Liquiritin and Liquiritigenin, in BV2 Cells and Mice Liver

open access: yes, 2018
This study provides the scientific basis for the anti-inflammatory effects of licorice extract in a t-BHP (tert-butyl hydrogen peroxide)-induced liver damage model and the effects of its ingredients, glycyrrhizic acid (GA), liquiritin (LQ) and ...
오세관, 유지연
core   +2 more sources

The Herbal Pair Daphniphyllum calycinum–Polygonum hydropiper Alleviates Gastric Mucosal Injury via Regulating Autophagy and Targeting the TLR4/NF‐κB/NLRP3 Pathway

open access: yesFood Science &Nutrition, Volume 14, Issue 4, April 2026.
The schematic diagram illustrated the proposed mechanism of DCPH in mouse macrophages. DCPH promotes autophagy to suppress the TLR4/NF‐κB/NLRP3 pathway and M1 polarization, thereby attenuating cellular oxidative stress and inflammation. ABSTRACT Gastric mucosal injury refers to the pathological changes characterized by congestion, edema, bleeding and ...
Yunyun Zhi   +6 more
wiley   +1 more source

Comparative Evaluation of Two Structurally Related Flavonoids, Isoliquiritigenin and Liquiritigenin, for Their Oral Infection Therapeutic Potential

open access: yes, 2016
Isoliquiritigenin (1) and liquiritigenin (2) are structurally related flavonoids found in a variety of plants. The purpose of this study was to perform a comparative analysis of biological properties of these compounds in regard to their therapeutic ...
Mark Feldman (559686)   +2 more
core   +1 more source

Secondary metabolites from the roots of Astragalus maximus [PDF]

open access: yesResearch Journal of Pharmacognosy, 2017
Background and objectives: Astragalus is one of the most abundant genera of flowering plants in Iran. There are a few reports on phytochemical investigation of this valuable genus.
J. Ghasemian-Yadegari   +3 more
doaj  

Longchai Decoction Treated the Fibrosis of Liver Induced by CCl4 Regulates Nrf2/GPX4 Pathway to Suppress Ferroptosis

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 8, April 2026.
ABSTRACT The aim of the study is to evaluate the therapeutic efficacy of Longchai Decoction (LCD), an empirical traditional Chinese medicine formula for liver disorders, on liver fibrosis (LF) and to elucidate its molecular mechanisms. A mouse model of LF and an erastin‐induced ferroptosis model was established in LX‐2 cells, which were then treated ...
Hui Wang   +3 more
wiley   +1 more source

Development and Validation of an UHPLC-QqQ-MS Technique for Simultaneous Determination of Ten Bioactive Components in Fangji Huangqi Tang

open access: yesJournal of Analytical Methods in Chemistry, 2016
The aim of this study is to develop an ultrahigh performance liquid chromatography method coupled with triple quadrupole mass spectrometry for simultaneous determination of tetrandrine, fangchinoline, atractylenolide I, atractylenolide III, calycosin-7-O-
Xiaoli Wang   +3 more
doaj   +1 more source

Bioactive Phytochemical Compounds in Medicago sativa L. (Alfalfa): A Systematic Review of Biological Properties and Therapeutic Relevance in Nutraceutical and Functional Food Implications

open access: yesFood Frontiers, Volume 7, Issue 2, March 2026.
ABSTRACT Medicago sativa L. (alfalfa) harbors a remarkably diverse reservoir of bioactive secondary metabolites. Flavonoids, isoflavones, and triterpenoid saponins dominate its bioactivity landscape, driving potent antioxidant, anti‐inflammatory, antimicrobial, estrogenic, hypolipidemic, and cytotoxic actions through redox modulation, membrane ...
Parham Joolaei Ahranjani   +3 more
wiley   +1 more source

Effects of oral liquiritigenin inoculation on gut microbiota and gene expression in intestinal and extraintestinal tissues of mice

open access: yesFrontiers in Microbiomes
IntroductionLiquiritigenin (LQ), a natural flavonoid found in traditional Chinese medicine and often administered orally, holds potential to affect both the gut and its microbiota, that potentially mediating or influencing its biological and ...
Zhaotaize Suo   +6 more
doaj   +1 more source

De novo biosynthesis of liquiritin in Saccharomyces cerevisiae

open access: yesActa Pharmaceutica Sinica B, 2020
Liquiritigenin (LG), isoliquiritigenin (Iso-LG), together with their respective glycoside derivatives liquiritin (LN) and isoliquiritin (Iso-LN), are the main active flavonoids of Glycyrrhiza uralensis, which is arguably the most widely used medicinal ...
Yan Yin   +5 more
doaj   +1 more source

GmMYB4 Positively Regulates Isoflavone Biosynthesis via the GmMAPK6‐GmMYB4‐MBW Module in Soybean

open access: yesPlant Biotechnology Journal, Volume 24, Issue 3, Page 1482-1499, March 2026.
ABSTRACT Isoflavones, a class of bioactive compounds predominantly found in leguminous plants, are largely responsible for their beneficial effects on human health. Although MYB transcription factors (TFs) are known to be crucial regulators of isoflavone biosynthesis in soybean, the precise mechanisms underlying their regulatory functions remain poorly
Changyun Yang   +12 more
wiley   +1 more source

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