Results 81 to 90 of about 3,770 (149)

Antibacterial Activity of the Flavonoids from Dalbergia odorifera on Ralstonia solanacearum

Molecules, 2011
Phytohemical investigation on the heartwood of Dalbergia odorifera resulted in the isolation of nine flavonoids. Their structures were elucidated as sativanone (1), (3R)-vestitone (2), (3R)-2',3',7-trihydroxy-4'-methoxyisoflavanone (3), (3R)-4'-methoxy-2'
Wenjian Zuo, Hongjin Bai, Mingfu Gong, Xiabo Zhao, Wenli Mei, Haofu Dai   +5 more
doaj   +1 more source

Integrating pharmacokinetics and network pharmacology to reveal mechanism of Shuangxia decoction in the treatment of insomnia

Journal of Holistic Integrative Pharmacy
Objective: Shuangxia Decoction is a traditional Chinese medicine classic formula used clinically to treat insomnia, consisting of Pinellia ternata (Banxia) and Prunella vulgaris (Xiakucao).
Ke Meng, Miao Xu, Yanping Liu, Ying Li, Wei Zhang, Yue He, Chenning Zhang   +6 more
doaj   +1 more source

Natural Flavonoids from Licorice as Potent Inhibitors of β-Glucuronidase Elucidated Through Computational Studies

Molecules
Gut bacterial β-glucuronidase is an important molecular target in several therapeutic applications. β-glucuronidase inhibitors can effectively alleviate gastrointestinal toxicity caused by certain drugs.
Jingli Liu, Yingying Xue, Hao Yan, Jing Zhou, Xu Long, Yuping Tang   +5 more
doaj   +1 more source

Estrogen receptor activation contributes to RNF146 expression and neuroprotection in Parkinson's disease models

, 2017
RNF146 is an E3 ubiquitin ligase that specifically recognizes and polyubiquitinates poly (ADP-ribose) (PAR)-conjugated substrates for proteasomal degradation. RNF146 has been shown to be neuroprotective against PAR polymerase-1 (PARP1)-induced cell death
Shin, Heung Mook, Kim, Dong Hoon, Ham, Sang Woo, Lee, Yun Song, Yunjong Lee, Cho, Myoung Lae, Kim, Hyo Jung, Lee, Yun Il, Juan C. Troncoso, Areum Jo, MyoungLae Cho, Yun-Il Lee, Joo-Ho Shin, Lee, Gum Hwa, Joon Yeop Lee, Troncoso, Juan C, Yun-Song Lee, Donghoon Kim, Gum Hwa Lee, Heung-Mook Shin, Hyojung Kim, Pletnikova, Olga, Lee, Yun Jong, Sangwoo Ham, Olga Pletnikova, Jo, Areum, Shin, Joo Ho, Lee, Joon Yeop   +27 more
core   +1 more source

Harnessing Liquiritigenin: A Flavonoid-Based Approach for the Prevention and Treatment of Cancer

Background/Objectives: The integration of natural compounds in cancer research marked a crucial shift in the modern medical landscape, through a growing acknowledgment of their potential as efficient, less toxic, and cost-effective alternatives to ...
Alqahtani, Mohammed S., Abbas, Mohamed, Sajeev, Anjana, Mohammed S. Alqahtani, Sethi, Gautam, Mohamed Abbas, Anjana Sajeev, Babu Santha Aswani, Aswani, Babu Santha, Kunnumakkara, Ajaikumar B., Gautam Sethi, Ajaikumar B. Kunnumakkara   +11 more
core   +1 more source

Antimutagenic components in Glycyrrhiza against N-methyl-N-nitrosourea in the Ames assay

, 2017
Antimutagenesis against N-nitroso compounds contribute to prevention of human cancer. We have found that Glycyrrhiza aspera ethanolic extract exhibits antimutagenic activity against N-methyl-N-nitrosourea (MNU) using the Ames assay with Salmonella ...
Keiko Inami (2651566), Yusuke Mine (2892194), Satomi Tanaka (836661), Yukiko Kojo (2892197), Masataka Mochizuki (2538808), Satoko Ishikawa (317467)   +5 more
core   +1 more source

Pharmacokinetic study of the prokinetic ABCs liquiritigenin, naringenin and hesperitin following the oral administration of Si–Ni–San decoction to functional dyspepsia patients

, 2019
1. The pharmacokinetics (PKs) analysis of compounds absorbed after the oral administration of Si-Ni-San (SNS) decoction to functional dyspepsia (FD) patients was designed to detect whether the effects were similar to prokinetics administered to healthy ...
Hongbin Yan (416795), Jianjun Xu (479527), Jian Wang (5901), Shaoqi Shi (5822318), Juan He (381034), Ping Ren (129621), Xi Huang (12172)   +6 more
core   +1 more source

Protective Effects of Liquiritigenin against Citrinin-Triggered, Oxidative-Stress-Mediated Apoptosis and Disruption of Embryonic Development in Mouse Blastocysts

, 2017
The mycotoxin citrinin (CTN), a natural contaminant in foodstuffs and animal feeds, exerts cytotoxic and genotoxic effects on various mammalian cells and embryos.
Wen-Hsiung Chan, Chien-Hsun Huang
core   +1 more source

HỢP CHẤT FLAVONOIT TỪ LÁ CÂY MUỒNG HOÀNG YẾN (CASSIA FISTULA L.)

Tạp chí Khoa học Đại học Cần Thơ, 2014
Hai hợp chất flavonoit, kaempferol (1) và liquiritigenin (2) đã được phân lập từ dịch chiết etyl axetat lá muồng hoàng  yến. Cấu trúc các hợp chất được xác định dựa vào phổ cộng hưởng từ hạt nhân 1 chiều, 2 chiều và kết hợp với tài liệu tham khảo.
Phạm Thị Nhật Trinh, Lê Tiến Nhung, Đặng Thị Cẩm Nhung   +2 more
doaj  

Effects of acute renal failure induced by uranyl nitrate on the pharmacokinetics of liquiritigenin and its two glucuronides, M1 and M2, in rats

, 2010
Objectives Liver disease and acute renal failure (ARF) are closely associated. The pharmacokinetics of liquiritigenin (LQ), a candidate therapy for inflammatory liver disease, and its metabolites M1 and M2 were evaluated in rats with ...
Jee W Lee, Hee E Kang, Myung G Lee, Seung R Baek, Se I Sohn   +4 more
core   +1 more source