Results 121 to 130 of about 6,058 (200)

LIS1 and DCX: Implications for Brain Development and Human Disease in Relation to Microtubules

Scientifica, 2013
Proper lamination of the cerebral cortex requires the orchestrated motility of neurons from their place of birth to their final destination. Improper neuronal migration may result in a wide range of diseases, including brain malformations, such as ...
Orly Reiner
doaj   +1 more source

A de novo microdeletion involving PAFAH1B (LIS1) related to lissencephaly phenotype

Data in Brief, 2015
Lissencephaly is a type of the congenital malformation of the brain. Due to the impairments of neuronal migration, patients show absence of brain convolution manifesting smooth brain surfaces.
Keiko Shimojima, Akihisa Okumura, Toshiyuki Yamamoto   +2 more
doaj   +1 more source

Altered extracellular matrix structure and elevated stiffness in a brain organoid model for disease

Nature Communications
The viscoelastic properties of tissues influence their morphology and cellular behavior, yet little is known about changes in these properties during brain malformations.
Maayan Karlinski Zur, Bidisha Bhattacharya, Inna Solomonov, Sivan Ben Dror, Alon Savidor, Yishai Levin, Amir Prior, Tamar Sapir, Talia Harris, Tsviya Olender, Rita Schmidt, J. M. Schwarz, Irit Sagi, Amnon Buxboim, Orly Reiner   +14 more
doaj   +1 more source

A LisH-domain protein interaction map reveals a Lis1-ARIH2-dynein regulatory axis

iScience
Summary: LisH-domain-containing proteins are involved in diverse cellular processes and disease mechanisms, yet their functional interaction landscape remains poorly characterized.
Devanshi Gupta, Subbareddy Maddika
doaj   +1 more source

The Drosophila cell adhesion molecule Neuroglian regulates Lissencephaly-1 localisation in circulating immunosurveillance cells

BMC Immunology, 2009
Background When the parasitoid wasp Leptopilina boulardi lays its eggs in Drosophila larvae phagocytic cells called plasmatocytes and specialized cells known as lamellocytes encapsulate the egg.
Williams Michael J
doaj   +1 more source

HIC1 : le noeud du problème en 17p13.3 ? [PDF]

, 2006
Le bras court du chromosome 17 (17p) est fréquemment altéré dans les cancers humains, notamment au niveau du gène p53. Cependant, dans certains cancers, des altérations en 17p concernent des régions distales de p53, en l’absence de toute mutation de ce ...
Chopin, Valérie, Leprince, Dominique
core  

LncRNA RASAL2-AS1 promotes METTL14-mediated m6A methylation in the proliferation and progression of head and neck squamous cell carcinoma

Cancer Cell International
Background Long non-coding RNAs (lncRNAs) are key regulators of the 6-methyladenosine (m6A) epigenetic modification, playing a role in the initiation and progression of tumors.
Meiting Rong, Ming Zhang, Feihong Dong, Ke Wu, Bingkun Cai, Jinrui Niu, Le Yang, Zhongyan Li, Hui-yi Lu   +8 more
doaj   +1 more source

Marcin Lis1*, Jacek Mazur1, Kinga Czechowska1, Joanna Karwan-Baczewska2, Adriana Wrona1

, 2023
Marcin Lis
openalex   +1 more source

LIS1 and dynein motor function in neuronal migration and development [PDF]

, 2001
Anthony Wynshaw‐Boris, Michael J. Gambello   +1 more
openalex   +1 more source

Kampen om LIS1

Tidsskrift for Den norske legeforening, 2022
openaire   +1 more source