Results 91 to 100 of about 7,838 (234)

The effect of insulin lispro on glycemic control in a large patient cohort.

, 2009
BACKGROUND: The use of rapid-acting insulin analogs and regular insulin differs considerably in countries throughout the world. We therefore studied how glycemic control has been affected by using insulin lispro in clinical practice over 5 years in 14 ...
Odén, Anders,, Michael Happich, Martin Fahlén, Lind, Marcus, Fahlén, Martin,, Fahl\ue9n, Martin, Fahlén, Martin, Od\ue9n, Anders, Eliasson, Björn, Anders Odén, Eliasson, Bj\uf6rn, Happich, Michael,, Odén, Anders, Björn Eliasson, Marcus Lind, Lind, Marcus,, Eliasson, Björn,, Happich, Michael   +17 more
core   +1 more source

Impact of system updates for sensor‐augmented pump therapy on glycemic management in Japanese individuals with type 1 diabetes (SAP‐J T1D study)

Journal of Diabetes Investigation, Volume 17, Issue 9, Page 1499-1505, September 2026.
Sequential updates from MiniMed 620G to 640G and then to 770G were associated with stepwise improvements in glycemic management in Japanese individuals with type 1 diabetes. The transition to MiniMed 640G was mainly associated with reduced hypoglycemia, whereas the subsequent transition to MiniMed 770G was associated with reduced hyperglycemia.
Shuichiro Saito, Akane Yamamoto, Yuya Miyazaki, Motoko Kobayashi, Mei Nakatsuji, Seiji Nishikage, Kai Yoshimura, Tomofumi Takayoshi, Wataru Ogawa, Yushi Hirota   +9 more
wiley   +1 more source

Subcutaneous injection of hyaluronidase with recombinant human insulin compared with insulin lispro in type 1 diabetes

, 2014
Aims Prandial treatment with human regular insulin for diabetes may result in early postprandial hyperglycaemia and late hypoglycaemia due to its slow onset and long duration of action.
Muchmore, D. B, J. B. Buse, Skyler, J. S, D. E. Vaughn, Garg, S. K, Buse, J. B, J. S. Skyler, S. K. Garg, D. B. Muchmore, Vaughn, D. E   +9 more
core   +1 more source

Characterisation of insulin analogues therapeutically available to patients. [PDF]

PLoS ONE, 2018
The structure and function of clinical dosage insulin and its analogues were assessed. This included 'native insulins' (human recombinant, bovine, porcine), 'fast-acting analogues' (aspart, glulisine, lispro) and 'slow-acting analogues' (glargine ...
Gary G Adams, Andrew Meal, Paul S Morgan, Qushmua E Alzahrani, Hanne Zobel, Ryan Lithgo, M Samil Kok, David T M Besong, Shahwar I Jiwani, Simon Ballance, Stephen E Harding, Naomi Chayen, Richard B Gillis   +12 more
doaj   +1 more source

Damping amyloid‐associated conformational fluctuations in a protein by an engineered diselenide bridge

Protein Science, Volume 35, Issue 8, August 2026.
Abstract Polypeptide cross‐β assembly, characteristic of diverse proteotoxic diseases, defines a general thermodynamic ground state and limits the shelf lives of peptide‐ and protein therapeutics. A model is provided by insulin. Although the hormone contains a predominance of α‐helix, its fibrils exhibit cross‐β reorganization.
Yanwu Yang, Balamurugan Dhayalan, Andreas Ehnbom, Orit Weil‐Ktorza, Norman Metanis, Michael A. Weiss   +5 more
wiley   +1 more source

Pharmacokinetics and pharmacodynamics of insulin lispro 25 versus the original preparation (Humalog®25) in Chinese healthy male volunteers

Frontiers in Pharmacology
Background: There are approximately 537 million adults with diabetes worldwide, and insulin still plays an important role in its treatment. However, the long-term use of insulin imposes a significant financial burden on patients.
Mingxue Zhu, Yuan Chen, Lei Wan, Zhongping Li, Junliang Pu, Chengyong Tang   +5 more
doaj   +1 more source

Lispro insulin and electrolyte supplementation for treatment of diabetic ketoacidosis in cats

Journal of Veterinary Internal Medicine, 2019
Background Intravenous continuous rate infusion (IVCRI) of lispro at a starting dose of 0.09 U/kg/h and the use of 0.9% sodium chloride (NaCl) for fluid resuscitation in cats with diabetic ketoacidosis (DKA) have not been reported.
Jodie D. Anderson, Danielle A. Rondeau, Rebecka S. Hess   +2 more
doaj   +1 more source

Transient Neonatal Diabetes Mellitus in a Very Preterm Infant due to ABCC8 Mutation

American Journal of Perinatology Reports, 2018
Neonatal diabetes mellitus (NDM) is a monogenic form of diabetes occurring within 6 months from birth. NDM can be permanent or transient (TNDM). We report the case of a preterm infant with TNDM due to an ABCC8 mutation identified by next-generation ...
Barbara Piccini, Caterina Coviello, Livia Drovandi, Artuso Rosangela, Francesca Monzali, Emilio Casalini, Sabrina Giglio, Sonia Toni, Carlo Dani   +8 more
doaj   +1 more source

Efficacy of Russian insulin biosimilars for type 1 diabetes in adolescents [PDF]

РМЖ. Мать и дитя, 2022
V.V. Platonov1,2, T.A. Dubinina1, E.M. Patrakeeva3, A.M. Rezvykh2, N.V. Kazachenko1 1K.A. Raukhfus Children’s City Multidisciplinary Clinical Center of High Medical Technologies,    St. Peterburg, Russian Federation 2St. Petersburg
V.V. Platonov, T.A. Dubinina, E.M. Patrakeeva, A.M. Rezvykh, N.V. Kazachenko   +4 more
doaj  

Hypoglycemic treatment of diabetic patients in the Emergency Department [PDF]

Farmacia Hospitalaria, 2016
Objectives: To analyze if the hypoglycemic therapy prescribed in the Emergency Department adapts to the consensus recommendations available, as well as to assess its clinical impact.
Carmen Caballero Requejo, Elena Urbieta Sanz, Abel Trujillano Ruiz, Celia García-Molina Sáez, María Onteniente Candela, Pascual Piñera Salmerón   +5 more
doaj   +1 more source