Results 101 to 110 of about 7,838 (234)

GIP in Cardiovascular and Kidney Disease: From Physiology to Pharmacology

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6509-6532, August 2026.
ABSTRACT Aims To provide a comprehensive overview of the cardiovascular and renal effects of glucose‐dependent insulinotropic polypeptide (GIP) by integrating its physiological role with recent human trial data on tirzepatide, the first dual GIP and glucagon‐like peptide‐1 (GLP‐1) receptor agonist.
Michelantonio De Fano, Line L. Haurum, Christine R. Schwarz, Francesca Porcellati, Andreas Andersen   +4 more
wiley   +1 more source

Menor incidência de hipoglicemia noturna com o uso de insulina lispro comparada à insulina humana regular no tratamento de pacientes com diabetes do tipo 1 [PDF]

, 2000
Insulin lispro is a human insulin analog of rapid onset of action and duration, which mimics the physiological insulin profile after a meal. We have evaluated the safety and efficacy of lispro insulin in comparison with human regular insulin in a ...
Kayath, Marcia J., Wajchenberg,Bernardo L., Chacra,Antônio R., Sena,Rita de Cássia, Ferreira, Sandra R.G., Ferreira,Sandra R.G., Lerário,Antonio C., Wajchenberg, Bernardo L., Oliveira,Odette de, Wajchenberg, Bernardo Leo, Sena, Rita de Cássia, Chacra, Antônio R., Lerário, Antonio C., Forti, Adriana Costa e [UNIFESP], Forti,Adriana C., Lerário, Antonio Carlos, Oliveira, Odette de, Ferreira, Sandra Roberta Gouvea [UNIFESP], Forti, Adriana C., Chacra, Antonio Roberto [UNIFESP], Monteiro, Odete de Oliveira [UNIFESP], Lopes, Carla F., Kayath,Marcia J., Lopes,Carla F.   +23 more
core   +1 more source

The Risk of Severe Hypoglycemia in Patients with Type 2 Diabetes Mellitus Starting Insulin Therapy with Premixed Insulin Analogues Taken Twice Daily: An Observational Study in Turkish Patients

Endocrinology Research and Practice, 2013
Purpose: To assess the risk of severe hypoglycemia in Turkish patients with type 2 diabetes mellitus (T2DM) starting insulin therapy with premixed insulin analogues alone or in combination with oral antihyperglycemic medications.
Adem Yürümez, Mustafa Sait Gönen, Ömer Hersek, Esma Altunoğlu, Halil Rakıcı, Jamie Scism-Bacon, Radhi Abdulnabi, Ali Ertekin   +7 more
doaj   +1 more source

Insulin lispro: a potential role in preventing nocturnal hypoglycaemia in young children with diabetes mellitus.

, 2003
AIMS: The long duration of action of soluble insulin given in the evening could contribute to the high prevalence of nocturnal hypoglycaemia seen in young children with Type 1 diabetes mellitus (T1DM).
Ford-Adams, ME, Dunger, DB, Ong, KL, Watts, AP, Murphy, NP, Moore, EJ, Edge, JA, Acerini, CL   +7 more
core   +1 more source

Pharmacokinetics of insulin lispro in type 2 diabetes during closed-loop insulin delivery

, 2014
Insulin pharmacokinetics is not well understood during continuous subcutaneous insulin infusion in type 2 diabetes (T2D). We analyzed data collected in 11 subjects with T2D [6 male, 9 white European and two of Indian ethnicity; age 59.7(12.1) years, BMI ...
Hovorka, Roman, Thabit, Hood; id_orcid, Kumareswaran, Kavita, Ruan, Yue   +3 more
core   +1 more source

Valutazione clinica e metabolica dell’impiego dell’insulina Lispro in pazienti con diabete mellito scompensato [PDF]

, 2005
The aim of the present work is to report preliminary results about the administration of an insulin analogue, LisPro, to treat diabetic chetoacidosis.
Uneddu, Antonio, Paolini, Tito Antonio
core   +1 more source

Efficacy and safety of switching to iGlarLixi from premixed insulin therapy in patients with type 2 diabetes: A real‐world experience

Diabetic Medicine, Volume 43, Issue 7, July 2026.
Abstract Aims Fixed‐ratio combinations such as iGlarLixi are recommended over premixed insulin as first‐line injectable therapy for type 2 diabetes mellitus (T2DM), yet real‐world evidence on transitions from premix to iGlarLixi remains limited. This study aimed to evaluate the efficacy and safety of switching from premixed insulin to iGlarLixi in a ...
Chun‐Jui Huang, Shun‐Jie Yang, Cheng‐Pin Cheng, Chun‐Hsing Lin, Ya‐Chun Lee, Harn‐Shen Chen   +5 more
wiley   +1 more source

Efficacy of insulin lispro in pregnancies complicated with pregestational diabetes mellitus

, 2009
Insulin is the mainstay in the management of pregnancies complicated by pregestational diabetes. Insulin analogues are useful in the non-pregnant state, leading to better glycaemic control.
Hughes, S. M., Banerjee, M.; id_orcid, Bhattacharya, A., Vice, P. A.   +3 more
core   +1 more source

Costo efectividad de insulina lispro protamina (NPL) vs. combinación de insulina NPH + insulina rápida

, 2020
RESUMEN Objetivo: La estrategia farmacológica en el manejo de la diabetes tipo 2 incluye la insulina lispro protamina (NPL) vs. combinación de insulina NPH + insulina rápida. El análisis costo efectividad aborda el aspecto económico y el epidemiológico
Martínez González,L, Vargas Daza,ER, Cervantes Becerra,RG, Villarreal Ríos,E, Montoya Hernández,MA, Galicia Rodríguez,L   +5 more
core   +1 more source

Clinical effects, cardiovascular and renal outcomes associated with rapid-acting insulin analogs among individuals with type 2 diabetes: a nation-wide observational cohort study

Clinical Diabetes and Endocrinology, 2017
Background Rapid-acting insulin analogs (RAIs) have not been examined for long-term safety in randomized clinical trials. We performed a nationwide longitudinal cohort study among individuals with type 2 diabetes (T2DM) to address cardiovascular safety ...
Ann-Marie Svensson, Mervete Miftaraj, Stefan Franzén, Björn Eliasson   +3 more
doaj   +1 more source