Results 11 to 20 of about 7,838 (234)

CamAPS FX Hybrid Closed-Loop with Ultra-Rapid Lispro Compared with Standard Lispro in Adults with Type 1 Diabetes: A Double-Blind, Randomized, Crossover Study [PDF]

open access: yesDiabetes Technology & Therapeutics, 2023
Introduction: To evaluate hybrid closed-loop with ultra-rapid insulin lispro (Lyumjev) compared with hybrid closed-loop with standard insulin lispro in adults with type 1 diabetes.
Munachiso Nwokolo   +9 more
semanticscholar   +7 more sources

A review of insulin lispro for the treatment of patients with type 2 diabetes mellitus [PDF]

open access: yesСахарный диабет, 2016
A critical aspect of the treatment of most patients with type 2 diabetes mellitus (T2DM) is the initiation (and subsequent intensification) of insulin therapy when lifestyle interventions and oral anti-hyperglycaemic drugs fail to maintain or improve ...
Marina V. Shestakova   +2 more
doaj   +2 more sources

Ultra rapid lispro improves postprandial glucose control versus lispro in combination with basal insulin: a study based on CGM in type 2 diabetes in China [PDF]

open access: yesFrontiers in Endocrinology
AimTo evaluate the efficacy and safety of URLi (ultra rapid lispro insulin) compared to insulin lispro as bolus insulin with basal insulin using CGM in the individuals with type 2 diabetes(T2D) in China.MethodsThis was a double-blind, randomized ...
Lu Yuan   +6 more
doaj   +2 more sources

Ultra-Rapid Lispro Improves Postprandial Glucose Control and Time in Range in Type 1 Diabetes Compared to Lispro: PRONTO-T1D Continuous Glucose Monitoring Substudy

open access: yesDiabetes Technology and Therapeutics, 2020
Background: This study evaluated glucose control by continuous glucose monitoring (CGM) during treatment with ultra-rapid lispro (URLi) or lispro used in combination with insulin glargine or degludec in adults with type 1 diabetes in a substudy of the ...
Maciej T. Małecki   +2 more
exaly   +2 more sources

Long-Term Efficacy and Safety of Ultra Rapid Lispro (URLi) in Adults with Type 1 Diabetes: The PRONTO-T1D Extension

open access: yesDiabetes Therapy, 2021
Introduction The PRONTO-T1D study, which evaluated the efficacy and safety of ultra rapid lispro (URLi) versus lispro in adults with type 1 diabetes (T1D), met the primary endpoint of noninferiority of HbA1c change from baseline compared to lispro at 26 ...
Juliana Bue-Valleskey, Dominik Dahl
exaly   +2 more sources

Cumulative clinical experience with use of insulin lispro: critical appraisal, role in therapy, and patient considerations

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2012
J Uy, L Fogelfeld, Y GuerraDivision of Endocrinology, Diabetes and Metabolism, John H Stroger Jr Hospital of Cook County, Chicago; Department of Endocrinology, Diabetes and Metabolism, Rush University Hospital, Chicago, IL, USAAbstract: We have now at ...
Uy J, Fogelfeld L, Guerra Y
doaj   +1 more source

Efficacy of insulin lispro in improving glycemic control in gestational diabetes

open access: yesIndian Journal of Endocrinology and Metabolism, 2014
Aim: To assess the safety and efficacy of insulin lispro in improving glycemic control in patients with gestational diabetes. Materials and Methods: A retrospective observational study was conducted at a single center on 201 gestational women with ...
M C Deepaklal   +3 more
doaj   +2 more sources

4S-fluorination of ProB29 in insulin lispro slows fibril formation

open access: yesJournal of Biological Chemistry
Recombinant insulin is a life-saving therapeutic for millions of patients affected by diabetes mellitus. Standard mutagenesis has led to insulin variants with improved control of blood glucose; for instance, the fast-acting insulin lispro contains two ...
Stephanie L. Breunig   +8 more
semanticscholar   +2 more sources

Ultra-Rapid Lispro Efficacy and Safety Compared to Humalog® in Japanese Patients with Type 1 Diabetes: PRONTO-T1D Subpopulation Analysis

open access: yesDiabetes Therapy, 2020
We evaluated the efficacy and safety of ultra-rapid lispro (URLi) in comparison to lispro in a subgroup analysis of Japanese adults with type 1 diabetes mellitus from the phase 3 PRONTO-T1D trial.
J. Miura   +3 more
exaly   +2 more sources

Tirzepatide vs Insulin Lispro Added to Basal Insulin in Type 2 Diabetes: The SURPASS-6 Randomized Clinical Trial.

open access: yesJournal of the American Medical Association (JAMA), 2023
Importance Tirzepatide is a glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist used for the treatment of type 2 diabetes.
J. Rosenstock   +7 more
semanticscholar   +1 more source

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