Results 31 to 40 of about 2,618 (245)
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Approach to Virgenes del Sol inn Cabaret ...: a Post-historic Condition and Literary Competence
Catedral Tomada: Revista de Crítica Literaria Latinoamericana, 2019 The purpose of this analysis is to propose a theoretical-critical-literary approach and from a post-historical edge to the poetic work Vírgenes del Sol Inn Cabaret: vien benidos a la máquina welcome to the tv by Alexis Figueroa (1986).
Jorge Rosas-Godoy
doaj +1 more source
Literary Competence Via L2 with L1
SSRN Electronic Journal, 2015 Learning the L2 may start with everyday basic communication skills but this aspect is not enough to develop higher order skills and deep learning. Thus the study aimed to determine the effectiveness of using L2 with L1 in teaching Philippine Literature to Elementary Education students of Surigao State College of Technology, City Campus during the first
openaire +1 more source
L1 Educational Studies in Language and Literature, 2012 4 p.
Janssen, Tanja +2 more
openaire +6 more sources
THE INFLUENCE OF VIRTUAL LITERATURE CIRCLES ON STUDENTS’ LITERARY COMPETENCE [PDF]
Journal of Nusantara Studies (JONUS), 2022 Background and Purpose: Despite being previously exposed to literature for many years during secondary school, Malaysian International Baccalaureate (IB) Diploma students tussle to cope with the English syllabus outlined by the International Baccalaureate Organisation (IBO).
openaire +1 more source
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Langue(s) & Parole, 2019 This study investigates the use of literary texts for intercultural learning using a Master course of English as a foreign language in Algeria as an empirical example.
Lamia Nemouchi, Michael Byram
doaj +1 more source
Literary Translation and Rewriting – Challenges and Perspectives [PDF]
Scientific Bulletin of the Politehnica University of Timişoara: Transactions on Modern Languages, 2021 The need for translation in a world of continuous change and exchange is unquestionable. Literary translation creates global communication and engages the readership’s interest in raising cultural awareness.
Liana Georgiana MOGA
doaj
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source