Results 31 to 40 of about 107,308 (356)

Pathological studies on postvaccinal reactions of Rift Valley fever in goats [PDF]

, 2009
RVF live attenuated vaccine (Smithburn strain) was evaluated by using goats as experimental animal. The results indicate that this vaccine cause severe deleterious pathological changes in liver especially in kids and causing abortion in pregnant does ...
Kamal Samia
core   +4 more sources

Envelope Determinants of Equine Lentiviral Vaccine Protection [PDF]

, 2013
Lentiviral envelope (Env) antigenic variation and associated immune evasion present major obstacles to vaccine development. The concept that Env is a critical determinant for vaccine efficacy is well accepted, however defined correlates of protection ...
A Kumar, A Kumar, AJ Mcmichael, AT Das, B Berkhout, BA Sponseller, BF Haynes, C Leroux, C Leroux, C Leroux, CH Grund, Charles J. Issel, CJ Issel, Corin Ezzelarab, D Shental-Bechor, David Horohov, DC Montefiori, DL Lichtenstein, DL Lichtenstein, EW Uhl, F Li, F Li, F Li, J Mills, JB Whitney, JK Craigo, JK Craigo, JK Craigo, JK Craigo, JK Craigo, JK Craigo, JK Craigo, JK Craigo, JM Ball, Jodi K. Craigo, K Abel, KA Hussain, L Coggins, L Howe, L Howe, Liu Chong, M Busch, MJ Papandreou, ML Raabe, MR Raabe, MR Reynolds, N Almond, PM Rwambo, PM Rwambo, R Hofmann-Lehmann, RC Montelaro, RF Cook, RM Ruprecht, Ronald C. Montelaro, RP Johnson, RP Johnson, RP Johnson, RR Amara, S Hambleton, SA Hammond, SA Hammond, SA Hammond, Sheila J. Cook, SL Payne, SM Blower, SM Harrold, SZ Wang, TL Tagmyer, TL Tagmyer, TW Baba, TW Baba, WC Koff, WM Bogers, Y Kono, YH Zheng, YH Zheng, Zhiping Ye   +76 more
core   +3 more sources

Live attenuated oral cholera vaccines

Expert Review of Vaccines, 2006
Live, orally administered, attenuated vaccine strains of Vibrio cholerae have many theoretical advantages over killed vaccines. A single oral inoculation could result in intestinal colonization and rapid immune responses, obviating the need for repetitive dosing. Live V.
Edward T, Ryan, Stephen B, Calderwood, Firdausi, Qadri   +2 more
openaire   +2 more sources

Intranasal delivery of a rationally attenuated SARS-CoV-2 is immunogenic and protective in Syrian hamsters

Nature Communications, 2022
Examples of effective live attenuated viral vaccines include the measles, mumps and rubella vaccine, as well as the chickenpox vaccine. In this work, the authors engineer a live attenuated SARS-CoV-2 virus that demonstrates attenuation in numerous in ...
Shufeng Liu, Charles B. Stauft, Prabhuanand Selvaraj, Prabha Chandrasekaran, Felice D’Agnillo, Chao-Kai Chou, Wells W. Wu, Christopher Z. Lien, Clement A. Meseda, Cyntia L. Pedro, Matthew F. Starost, Jerry P. Weir, Tony T. Wang   +12 more
doaj   +1 more source

Protection efficacy of Argentinian isolates of Mycobacterium avium subsp. paratuberculosis with different genotypes and virulence in a murine model [PDF]

, 2018
Paratuberculosis is a chronic disease caused by Mycobacterium avium subsp. paratuberculosis (Map). The disease causes economic losses and, therefore, it is imperative to follow proper control strategies, which should include an effective vaccine. Several
Alvarado Pinedo, María Fiorella, Colombatti Olivieri, María Alejandra, Delgado, Fernando Oscar, Gravisaco, Maria Jose Federica, Mon, Maria Laura, Moyano, Roberto Damian, Romano, Maria Isabel, Santangelo, María de la Paz, Travería, Gabriel Eduardo   +8 more
core   +1 more source

Five-year antibody persistence in children after one dose of inactivated or live attenuated hepatitis A vaccine

Human Vaccines & Immunotherapeutics, 2017
In China, both inactivated hepatitis A (HA) vaccine and live attenuated HA vaccine are available. We conducted a trial to evaluate 5-year immune persistence induced by one dose of inactivated or live attenuated HA vaccines in children.
Zhilun Zhang, Xiangjun Zhu, Yuansheng Hu, Miao Liang, Jin Sun, Yufei Song, Qi Yang, Haiquan Ji, Gang Zeng, Lifei Song, Jiangting Chen   +10 more
doaj   +1 more source

Zika Virus Attenuation by Codon Pair Deoptimization Induces Sterilizing Immunity in Mouse Models. [PDF]

, 2018
Zika virus (ZIKV) infection during the large epidemics in the Americas is related to congenital abnormities or fetal demise. To date, there is no vaccine, antiviral drug, or other modality available to prevent or treat Zika virus infection.
Hu, Q, Ke, X, Li, P, Liu, Y, Luo, D, Miao, Y, Sun, J, Tan, Z, Wang, H, Wang, T, Xu, F, Zhang, Y, Zheng, Z   +12 more
core   +1 more source

Oronasal or Intramuscular Immunization with a Thermo-Attenuated ASFV Strain Provides Full Clinical Protection against Georgia 2007/1 Challenge

Viruses, 2022
African swine fever (ASF) is a contagious viral disease of suids that induces high mortality in domestic pigs and wild boars. Given the current spread of ASF, the development of a vaccine is a priority.
Olivier Bourry, Evelyne Hutet, Mireille Le Dimna, Pierrick Lucas, Yannick Blanchard, Amélie Chastagner, Frédéric Paboeuf, Marie-Frédérique Le Potier   +7 more
doaj   +1 more source

Biomarkers of Safety and Immune Protection for Genetically Modified Live Attenuated Leishmania Vaccines Against Visceral Leishmaniasis – Discovery and Implications [PDF]

, 2014
Despite intense efforts there is no safe and efficacious vaccine against visceral leishmaniasis, which is fatal and endemic in many tropical countries. A major shortcoming in the vaccine development against blood borne parasitic agents such as Leishmania
Angamuthu Selvapandiyan, Hira L. Nakhasi, Kumar Avishek, Poonam Salotra, Ranadhir Dey, Sreenivas Gannavaram   +5 more
core   +3 more sources

Research note: Comparison of live attenuated and non-attenuated Eimeria vaccines on safety following overdose administration using the European pharmacopoeia monograph model

Poultry Science
Live non-attenuated and attenuated coccidiosis vaccines are available and induce a solid immune response to Eimeria spp. However, knowledge regarding the safety of live non-attenuated Eimeria vaccines is still limited.
Marc Pagès, Andreu Albó, Gregori Bech-Sàbat, Roser Morató, Joan Molist-Badiola, Martina Dardi   +5 more
doaj   +1 more source