Results 21 to 30 of about 131,394 (205)

Summary of the Current Status of African Swine Fever Vaccine Development in China

Vaccines, 2023
African swine fever (ASF) is a highly lethal and contagious disease of domestic pigs and wild boars. There is still no credible commercially available vaccine.
Naijun Han, Hailong Qu, Tiangang Xu, Yongxin Hu, Yongqiang Zhang, Shengqiang Ge   +5 more
doaj   +1 more source

Pathogenicity and transmissibility studies on live attenuated duck enteritis virus vaccine in non-target species

Frontiers in Microbiology, 2022
In the second half of 2021, a highly pathogenic case occurred in a mixed chicken and duck family farm in Guangdong, China. After the duck flocks were immunized with live attenuated duck enteritis virus vaccine (live attenuated DEV vaccine), the chickens ...
Jie Kong, Jie Kong, Jie Kong, Keyu Feng, Keyu Feng, Keyu Feng, Keyu Feng, Qiqi Zhao, Qiqi Zhao, Qiqi Zhao, Yazheng Chen, Yazheng Chen, Yazheng Chen, Jinfeng Wang, Jinfeng Wang, Jinfeng Wang, Sheng Chen, Sheng Chen, Sheng Chen, Guanming Shao, Guanming Shao, Guanming Shao, Liqin Liao, Liqin Liao, Liqin Liao, Yajuan Li, Yajuan Li, Yajuan Li, Zi Xie, Zi Xie, Zi Xie, Xinheng Zhang, Xinheng Zhang, Xinheng Zhang, Xinheng Zhang, Qingmei Xie, Qingmei Xie, Qingmei Xie, Qingmei Xie   +38 more
doaj   +1 more source

Improvements to the live-attenuated Newcastle disease virus vaccine using Carbopol® 940 as a stabilizer [PDF]

Veterinary World, 2020
Background and Aim: One strategy that can be used to stabilize vaccines is to convert them into a dry powder. This can protect the integrity of the active ingredients as well as vaccine antigenicity during manufacture, storage, and transport.
Mahmoud Mohamed Abd El-Moneam, Nada Adel Fathy, Naglaa I. Ali, Heba Mohamed El Naggar   +3 more
doaj   +1 more source

Nanopore sequencing approach for variation detection of a live attenuated Newcastle disease virus vaccine

BioTechniques, 2022
Live attenuated Newcastle disease virus (NDV) vaccines have been used widely to protect chickens against Newcastle disease. However, the vaccine issues caused by genome mutations can seriously affect poultry health. In this study, the authors demonstrate
Kai Sun, Chunyu Tian, Mengyu Cao, Xiaoping Yu, Chuanlin Yin, Zihong Ye   +5 more
doaj   +1 more source

Recombinant ASF Live Attenuated Virus Strains as Experimental Vaccine Candidates

Viruses, 2022
African swine fever (ASF) is causing a pandemic affecting swine in a large geographical area of the Eastern Hemisphere, from Central Europe to East and Southeast Asia, and recently in the Americas, the Dominican Republic and Haiti. The etiological agent,
D. Gladue, M. Borca
semanticscholar   +1 more source

Comparative Study of the Temperature Sensitive, Cold Adapted and Attenuated Mutations Present in the Master Donor Viruses of the Two Commercial Human Live Attenuated Influenza Vaccines

Viruses, 2019
Influenza viruses cause annual, seasonal infection across the globe. Vaccination represents the most effective strategy to prevent such infections and/or to reduce viral disease.
Laura Rodriguez, Pilar Blanco-Lobo, Emma C. Reilly, Tatsuya Maehigashi, Aitor Nogales, Andrew Smith, David J. Topham, Stephen Dewhurst, Baek Kim, Luis Martínez-Sobrido   +9 more
doaj   +1 more source

A codon-pair deoptimized live-attenuated vaccine against respiratory syncytial virus is immunogenic and efficacious in non-human primates.

Vaccine, 2020
Despite a critical need for a respiratory syncytial virus (RSV) vaccine and decades of development efforts, a vaccine to protect infants, elderly, and other at-risk populations from RSV infection remains elusive.
S. Mueller, C. Stauft, R. Kalkeri, Fusataka Koidei, Anna S. Kushnir, S. Tasker, J. R. Coleman   +6 more
semanticscholar   +1 more source

Next-Generation Leishmanization: Revisiting Molecular Targets for Selecting Genetically Engineered Live-Attenuated Leishmania

Microorganisms, 2023
Despite decades of research devoted to finding a vaccine against leishmaniasis, we are still lacking a safe and effective vaccine for humans. Given this scenario, the search for a new prophylaxis alternative for controlling leishmaniasis should be a ...
Paulo O. L. Moreira, Paula M. Nogueira, Rubens L. Monte-Neto   +2 more
doaj   +1 more source

Live attenuated intranasal influenza vaccine [PDF]

Human Vaccines & Immunotherapeutics, 2012
Annual vaccination is the most effective means of preventing and controlling influenza epidemics, and the traditional trivalent inactivated vaccine (TIV) is by far the most widely used. Unfortunately, it has a number of limitations, the most important of which is its poor immunogenicity in younger children and the elderly, the populations at greatest ...
S. Esposito, V. Montinaro, E. Groppali, R. Tenconi, M. Semino, N. Principi   +5 more
openaire   +5 more sources

Could an Unrelated Live Attenuated Vaccine Serve as a Preventive Measure To Dampen Septic Inflammation Associated with COVID-19 Infection?

mBio, 2020
We propose the concept that administration of an unrelated live attenuated vaccine, such as MMR (measles, mumps, rubella), could serve as a preventive measure against the worst sequelae of coronavirus disease 2019 (COVID-19).
P. Fidel, Mairi C. Noverr
semanticscholar   +1 more source