Cold adapted live attenuated influenza vaccines can effectively prevent human disease and death caused by influenza virus. Since chicken embryos are used as the culture substrate for the large-scale production of influenza vaccines, cold adapted live ...
Min Wu +14 more
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Rational Development of Live-Attenuated Zika Virus Vaccines
Zika virus (ZIKV), a re-emerging mosquito-borne flavivirus, has caused outbreaks in Africa, Asia, the Pacific, and, more recently, in the Americas. ZIKV has been associated with the neurological autoimmune disorder Guillain–Barre syndrome in adults and ...
Awadalkareem Adam +2 more
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Envelope Determinants of Equine Lentiviral Vaccine Protection [PDF]
Lentiviral envelope (Env) antigenic variation and associated immune evasion present major obstacles to vaccine development. The concept that Env is a critical determinant for vaccine efficacy is well accepted, however defined correlates of protection ...
A Kumar +76 more
core +7 more sources
Live Viral Vaccine Neurovirulence Screening: Current and Future Models
Live viral vaccines are one of the most successful methods for controlling viral infections but require strong evidence to indicate that they are properly attenuated.
Corey May Fulton, Wendy J. Bailey
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Improvements to the live-attenuated Newcastle disease virus vaccine using Carbopol® 940 as a stabilizer [PDF]
Background and Aim: One strategy that can be used to stabilize vaccines is to convert them into a dry powder. This can protect the integrity of the active ingredients as well as vaccine antigenicity during manufacture, storage, and transport.
Mahmoud Mohamed Abd El-Moneam +3 more
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Evaluate Risk Analysis of Measurement Uncertainty (MU) of Different Methods Applied for Veterinary Vaccines Evaluation [PDF]
Veterinary Serum and Vaccine Research Institute (VSVRI ) objected to producing highly efficient vaccines from reference or local isolates according to the international specifications for protecting animals and poultry against different diseases and ...
Hala Elsawy +5 more
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Formulation of a live bacterial vaccine for stable room temperature storage results in loss of acid, bile and bile salt resistance [PDF]
Live bacterial vaccines have great promise both as vaccines against enteric pathogens and as heterologous antigen vectors against diverse diseases. Ideally, room temperature stable dry formulations of live bacterial vaccines will allow oral vaccination ...
Edwards, Alexander D. +1 more
core +1 more source
Safety of measles-containing vaccines in post-marketing surveillance in Anhui, China. [PDF]
The safety of measles vaccination is of great interest and importance to public health practice and the general society. We have analyzed the adverse events following immunization (AEFIs) of currently used measles-containing vaccines (including live ...
Fan-Ya Meng +7 more
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Live attenuated intranasal influenza vaccine [PDF]
Annual vaccination is the most effective means of preventing and controlling influenza epidemics, and the traditional trivalent inactivated vaccine (TIV) is by far the most widely used. Unfortunately, it has a number of limitations, the most important of which is its poor immunogenicity in younger children and the elderly, the populations at greatest ...
S. Esposito +5 more
openaire +5 more sources
LIVE ATTENUATED VACCINES FOR THE IMMUNOPROPHYLAXIS
The review focuses on the history of the production of live antiviral vaccines and their use for the prevention of infectious diseases. It was noted that before the beginning of the 20th century, only three live vaccines were developed and put into ...
O. A. Shamsutdinova
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