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Human and bovine respiratory syncytial virus vaccine research and development [PDF]
, 2008 Human (HRSV) and bovine (BRSV) respiratory syncytial viruses (RSV) are two closely related viruses, which are the most important causative agents of respiratory tract infections of young children and calves, respectively.
Deplanche, Martine +2 more
core +2 more sources
Development of a novel equine influenza virus live-attenuated vaccine [PDF]
, 2018 H3N8 equine influenza virus (EIV) is an important and significant respiratory pathogen of horses. EIV is enzootic in Europe and North America, mainly due to the suboptimal efficacy of current vaccines. We describe, for the first time, the generation of a
Chambers, Thomas M. +5 more
core +1 more source
Progress and problems in vaccination against necrotic enteritis in broiler chickens [PDF]
, 2014 Necrotic enteritis in broilers is caused by Clostridium perfringens type A strains that produce the NetB toxin. Necrotic enteritis is one of the gastrointestinal diseases in poultry that has gained worldwide importance during the last decade due to ...
Ducatelle, Richard +4 more
core +2 more sources
Live Attenuated Varicella Vaccine
The Journal of Pediatrics, 1984 Live attenuated varicella vaccine will in all probability soon be licensed in the United States for immunization of healthy children and adults and certain immunocompromised children. This vaccine can be expected to protect susceptibles from varicella (or to modify it) in those subsequently exposed to the wild virus.
openaire +7 more sources
Live vaccination tactics: possible approaches for controlling visceral leishmaniasis
Frontiers in Immunology, 2014 Vaccination with durable immunity is the main goal and fundamental to control leishmaniasis. To stimulate the immune response, small numbers of parasites are necessary to be presented in the mammalian host.
Noushin eSaljoughian +2 more
doaj +1 more source
Development of dengue vaccines [PDF]
, 2018 Background: Dengue virus (DENV) causes up to 390 million infections yearly, of which 96 million are clinically manifested. Approximately 500,000 people with severe dengue require hospitalization each year and there are at least 25,000 deaths among ...
Lim, Chee Siean *, Poh, Chit Laa *
core +3 more sources
Repurposing mucosal delivery devices for live attenuated tuberculosis vaccines
Frontiers in Immunology, 2023 Tuberculosis (TB) remains one of the most lethal infectious diseases globally. The only TB vaccine approved by the World Health Organization, Bacille Calmette-Guérin (BCG), protects children against severe and disseminated TB but provides limited ...
Munish Puri +4 more
doaj +1 more source
Zika Virus Attenuation by Codon Pair Deoptimization Induces Sterilizing Immunity in Mouse Models. [PDF]
, 2018 Zika virus (ZIKV) infection during the large epidemics in the Americas is related to congenital abnormities or fetal demise. To date, there is no vaccine, antiviral drug, or other modality available to prevent or treat Zika virus infection.
Hu, Q +12 more
core +1 more source
Generation of DelNS1 Influenza Viruses: a Strategy for Optimizing Live Attenuated Influenza Vaccines
mBio, 2019 Nonstructural protein 1 (NS1) of influenza virus is a key virulence element with multifunctional roles in virus replication and a potent antagonist of host immune response.
Pui Wang +17 more
doaj +1 more source
Live attenuated oral cholera vaccines
Expert Review of Vaccines, 2006 Live, orally administered, attenuated vaccine strains of Vibrio cholerae have many theoretical advantages over killed vaccines. A single oral inoculation could result in intestinal colonization and rapid immune responses, obviating the need for repetitive dosing. Live V.
Edward T, Ryan +2 more
openaire +2 more sources