Results 31 to 40 of about 59,179 (315)

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

open access: yesHepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan   +19 more
wiley   +1 more source

Aflatoxin exposure and viral hepatitis in the etiology of liver cirrhosis in the Gambia, West Africa. [PDF]

open access: yes, 2008
BACKGROUND: Cirrhosis of the liver is thought to be a major cause of morbidity and mortality in sub-Saharan Africa, but few controlled studies on the etiology of cirrhosis have been conducted in this region.
James J. Goedert   +21 more
core   +1 more source

Medical Management of Chronic Cholestatic Liver Diseases

open access: yesCanadian Journal of Gastroenterology, 2000
The purpose of the present review is to discuss the diagnosis and management of cholestatic liver diseases. Differential diagnoses to consider are described, including causes of extrahepatic biliary obstruction such as gallstones, strictures ...
Andrea A Gossard, Keith D Lindor
doaj   +1 more source

Primary biliary cirrhosis and autoimmune cholangitis are not associated with coeliac disease in Crete

open access: yesBMC Gastroenterology, 2002
Background An increased prevalence of coeliac disease in patients with primary biliary cirrhosis has been recently reported. However, in other studies the association has not been confirmed.
Dimoulios Philippos   +8 more
doaj   +1 more source

Copper and Manganese Concentrations in Biliary Cirrhosis of Liver [PDF]

open access: yesBMJ, 1968
The presence of large amounts of copper in the liver in primary biliary cirrhosis has been confirmed; a similar increase is not found in cases of long-standing extrahepatic biliary obstruction. The serum caeruloplasmin levels are raised in primary and secondary biliary cirrhosis, but this increase does not appear to be related to the degree of increase
M, Worwood, D M, Taylor, A H, Hunt
openaire   +2 more sources

Attacking the public health crisis of hepatocellular carcinoma at its roots

open access: yesHepatology, EarlyView., 2022
Abstract As the third most common cause of cancer‐related death worldwide with significant mortality rates in the United States, hepatocellular carcinoma has strong association with cirrhosis and chronic hepatitis B virus (HBV) with a growing at‐risk population from the rise in chronic liver disease from alcohol use and nonalcoholic fatty liver disease.
Hannah M. Lee   +3 more
wiley   +1 more source

Primary Biliary Cirrhosis and Hemolytic Anemia Confusing Serum Bilirubin Levels

open access: yesCanadian Journal of Gastroenterology, 2000
Hemolysis is observed in more than 50% of patients with cirrhosis. However, there has been little documention of the association of primary biliary cirrhosis with autoimmune hemolytic anemia.
M Brackstone, Cameron N Ghent
doaj   +1 more source

Acetylcholine receptor antibody positive generalized Myasthenia gravis in association with Primary Biliary Cirrhosis

open access: yesAnnals of Hepatology, 2010
Primary Biliary Cirrhosis and Myasthenia Gravis are both autoimmune conditions, however, there are only rare case reports of their association. This is a case report of acetylcholine receptor antibody positive generalized myasthenia gravis in a female ...
Heather Taddy   +3 more
doaj   +1 more source

Liver Transplantation for Primary Biliary Cirrhosis

open access: yes, 2014
Primary biliary cirrhosis (PBC) is one of the most common indications for adult liver transplantation in both Western countries and Japan. Recently, the number of liver transplantations for PBC has shown a decreasing trend in Europe and the United States, likely due to advances in medical therapies using ursodeoxycholic acid.
GENDA, Takuya, ICHIDA, Takafumi
openaire   +2 more sources

Health disparities in chronic liver disease

open access: yesHepatology, EarlyView., 2022
Abstract The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.
Ani Kardashian   +3 more
wiley   +1 more source

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