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Sphingomyelinases and Liver Diseases [PDF]
Biomolecules, 2020Sphingolipids (SLs) are critical components of membrane bilayers that play a crucial role in their physico-chemical properties. Ceramide is the prototype and most studied SL due to its role as a second messenger in the regulation of multiple signaling pathways and cellular processes.
Naroa Insausti-Urkia+3 more
openaire +4 more sources
Characterization of Frequency-Dependent Material Properties of Human Liver and its Pathologies Using an Impact Hammer [PDF]
Medical Image Analysis, 2011, Vol. 15, No.1, pp. 45-52, 2021The current methods for characterization of frequency-dependent material properties of human liver are very limited. In fact, there is almost no data available in the literature showing the variation in dynamic elastic modulus of healthy or diseased human liver as a function of excitation frequency.
arxiv +1 more source
Critical Role of microRNA-21 in the Pathogenesis of Liver Diseases [PDF]
, 2020MicroRNAs are small non-coding RNAs that range in length from 18 to 24 nucleotides. As one of the most extensively studied microRNAs, microRNA-21 (miR-21) is highly expressed in many mammalian cell types.
Han, Sen+4 more
core +1 more source
Canadian Journal of Gastroenterology and Hepatology, 1999
A mild to moderate iron excess is found in patients with liver diseases apparently unrelated to genetic hemochromatosis. Iron appears to affect the natural history of hepatitis C virusārelated chronic liver diseases, alcoholic liver disease and nonalcoholic steatohepatitis by leading to a more severe fibrosis and thus aiding the evolution to cirrhosis ...
S.R. Fargion+3 more
openaire +6 more sources
A mild to moderate iron excess is found in patients with liver diseases apparently unrelated to genetic hemochromatosis. Iron appears to affect the natural history of hepatitis C virusārelated chronic liver diseases, alcoholic liver disease and nonalcoholic steatohepatitis by leading to a more severe fibrosis and thus aiding the evolution to cirrhosis ...
S.R. Fargion+3 more
openaire +6 more sources
Genome-wide and Mendelian randomisation studies of liver MRI yield insights into the pathogenesis of steatohepatitis [PDF]
, 2020Background A non-invasive method to grade the severity of steatohepatitis and liver fibrosis is magnetic resonance imaging (MRI) based corrected T1 (cT1).
Banerjee, R+25 more
core +3 more sources
Realistic Ultrasound Image Synthesis for Improved Classification of Liver Disease [PDF]
, 2021With the success of deep learning-based methods applied in medical image analysis, convolutional neural networks (CNNs) have been investigated for classifying liver disease from ultrasound (US) data. However, the scarcity of available large-scale labeled US data has hindered the success of CNNs for classifying liver disease from US data.
arxiv +1 more source
Bile Acid Receptor Therapeutics Effects on Chronic Liver Diseases [PDF]
, 2020In the past ten years, our understanding of the importance of bile acids has expanded from fat absorption and glucose/lipid/energy homeostasis into potential therapeutic targets for amelioration of chronic cholestatic liver diseases.
Alpini, Gianfranco+4 more
core +1 more source
Liver Tumor Prediction with Advanced Attention Mechanisms Integrated into a Depth-Based Variant Search Algorithm [PDF]
, 2023In recent days, Deep Learning (DL) techniques have become an emerging transformation in the field of machine learning, artificial intelligence, computer vision, and so on. Subsequently, researchers and industries have been highly endorsed in the medical field, predicting and controlling diverse diseases at specific intervals.
arxiv +1 more source
Pediatric liver diseases: current challenges and future perspectives [PDF]
, 2015Chronic liver diseases in children represent a rising problem with significant effects on public health. In fact, several pediatric liver diseases are precursors of adult chronic hepatopathies, cirrhosis and hepatocellular carcinoma.
Alisi, Anna+5 more
core +1 more source