Results 1 to 10 of about 15,995,904 (363)

Malnutrition, Frailty, and Sarcopenia in Patients With Cirrhosis: 2021 Practice Guidance by the American Association for the Study of Liver Diseases

Hepatology, 2021
This is the first American Association for the Study of Liver Diseases (AASLD) Practice Guidance on the management of malnutrition, frailty, and sarcopenia in patients with cirrhosis.
J. Lai, P. Tandon, W. Bernal, E. Tapper, U. Ekong, S. Dasarathy, Elizabeth J. Carey   +6 more
semanticscholar   +1 more source

Characteristics and Clinical Significance of Intestinal Microbiota in Patients with Chronic Hepatitis B Cirrhosis and Type 2 Diabetes Mellitus

Journal of Diabetes Research, 2022
Background. Chronic hepatitis B cirrhosis is often accompanied by glucose metabolism disorder, and intestinal microbiota was closely related to both cirrhosis and diabetes.
Xiu Sun, Xin Chi, Yingying Zhao, Shunai Liu, Huichun Xing   +4 more
doaj   +1 more source

Metabolic dysfunction-associated steatotic liver disease: Update and impact of new nomenclature on the American Association for the Study of Liver Diseases practice guidance on nonalcoholic fatty liver disease.

Hepatology, 2023
This commentary discusses how clinicians and various stakeholders can utilize the recently published American Association for the Study of Liver Diseases nonalcoholic fatty liver disease (AASLD NAFLD) Practice Guidance in light of the change in the ...
F. Kanwal, B. Neuschwander-Tetri, R. Loomba, M. Rinella   +3 more
semanticscholar   +1 more source

Mitochondrial alterations in fatty liver diseases.

Journal of Hepatology, 2022
Fatty liver diseases increasingly arise from common metabolic diseases, but also from xenobiotics and excessive alcohol use. Despite different etiology, they share several similarities regarding their toxic effects on hepatic mitochondrial functionality ...
B. Fromenty, M. Roden
semanticscholar   +1 more source

EASL Clinical Practice Guidelines on the management of liver diseases in pregnancy.

Journal of Hepatology, 2023
Liver diseases in pregnancy comprise both gestational liver disorders and acute and chronic hepatic disorders occurring coincidentally in pregnancy.
C. Williamson, Melanie Nana, L. Poon, L. Kupčinskas, R. Painter, G. Taliani, M. Heneghan, H. Marschall, U. Beuers   +8 more
semanticscholar   +1 more source

Fenofibrate in primary sclerosing cholangitis; a randomized, double‐blind, placebo‐controlled trial

Pharmacology Research & Perspectives, 2022
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with no medical treatment proven to improve survival and postpone liver transplantation. Previous studies have shown the effectiveness of fibrates in primary biliary cholangitis.
Behzad Hatami, Mozhde Mosala, Amir Hossein Hassani, Mohammad Javad Ehsani Ardakani, Samira Gholami, Mohammad Reza Zali   +5 more
doaj   +1 more source

Pathophysiological Roles of Mucosal-Associated Invariant T Cells in the Context of Gut Microbiota-Liver Axis

Microorganisms, 2021
Mucosal-associated invariant T (MAIT) cells are a subset of T lymphocytes expressing a semi-invariant T-cell receptor (TCR) present as TCR Vα7.2-Jα33 in humans and TCR Vα19-Jα33 in mice.
Yoseph Asmelash Gebru, Mi Ran Choi, Ganesan Raja, Haripriya Gupta, Satya Priya Sharma, Ye Rin Choi, Hyeong Seop Kim, Sang Jun Yoon, Dong Joon Kim, Ki Tae Suk   +9 more
doaj   +1 more source

Mitochondrial dysfunction: A promising therapeutic target for liver diseases

Genes and Diseases, 2023
The liver is an important metabolic and detoxification organ and hence demands a large amount of energy, which is mainly produced by the mitochondria.
Ping Chen, Li-Chao Yao, Mengqin Yuan, Zheng Wang, Qiu-Yu Zhang, Yingan Jiang, Lan-Juan Li   +6 more
semanticscholar   +1 more source

Autophagy in liver diseases: A review

Molecular Aspects of Medicine, 2021
The liver is a highly dynamic metabolic organ that plays critical roles in plasma protein synthesis, gluconeogenesis and glycogen storage, cholesterol metabolism and bile acid synthesis as well as drug/xenobiotic metabolism and detoxification.
Hui Qian, Xiao-Juan Chao, Jessica A. Williams, S. Fulte, Tian-Gang Li, Ling Yang, Wen-Xing Ding   +6 more
semanticscholar   +1 more source

Dynamic changes of phenotype and function of natural killer cells in peripheral blood before and after thermal ablation of hepatitis B associated hepatocellular carcinoma and their correlation with tumor recurrence

BMC Cancer, 2023
Background Thermal therapy induces an immune response in patients with hepatocellular carcinoma (HCC), but the dynamic characteristics of the natural killer (NK) cell immune response post-thermal ablation remain unclear.
Hai-Yan Wang, Xiong-Wei Cui, Yong-Hong Zhang, Yu Chen, Ning-Ning Lu, Li Bai, Zhong-Ping Duan   +6 more
doaj   +1 more source