Results 1 to 10 of about 1,097,169 (165)

Characteristics and Clinical Significance of Intestinal Microbiota in Patients with Chronic Hepatitis B Cirrhosis and Type 2 Diabetes Mellitus

open access: yesJournal of Diabetes Research, 2022
Background. Chronic hepatitis B cirrhosis is often accompanied by glucose metabolism disorder, and intestinal microbiota was closely related to both cirrhosis and diabetes.
Xiu Sun   +4 more
doaj   +1 more source

Fenofibrate in primary sclerosing cholangitis; a randomized, double‐blind, placebo‐controlled trial

open access: yesPharmacology Research & Perspectives, 2022
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with no medical treatment proven to improve survival and postpone liver transplantation. Previous studies have shown the effectiveness of fibrates in primary biliary cholangitis.
Behzad Hatami   +5 more
doaj   +1 more source

Pathophysiological Roles of Mucosal-Associated Invariant T Cells in the Context of Gut Microbiota-Liver Axis

open access: yesMicroorganisms, 2021
Mucosal-associated invariant T (MAIT) cells are a subset of T lymphocytes expressing a semi-invariant T-cell receptor (TCR) present as TCR Vα7.2-Jα33 in humans and TCR Vα19-Jα33 in mice.
Yoseph Asmelash Gebru   +9 more
doaj   +1 more source

Dynamic changes of phenotype and function of natural killer cells in peripheral blood before and after thermal ablation of hepatitis B associated hepatocellular carcinoma and their correlation with tumor recurrence

open access: yesBMC Cancer, 2023
Background Thermal therapy induces an immune response in patients with hepatocellular carcinoma (HCC), but the dynamic characteristics of the natural killer (NK) cell immune response post-thermal ablation remain unclear.
Hai-Yan Wang   +6 more
doaj   +1 more source

Antiviral Therapy for a Postpartum Flare in Women with Chronic HBV Infection Shortens the ALT Recovery Time and Reduces Hepatitis Re-Flare Rates within 4 years

open access: yesCanadian Journal of Gastroenterology and Hepatology, 2022
Background. Few studies explored whether anti-hepatitis B virus (HBV) therapy should be initiated during postpartum hepatitis flare. Aim. This study aimed to analyze the effect of anti-HBV therapy on postpartum hepatitis flare and evaluate the prognosis ...
Min Quan   +3 more
doaj   +1 more source

Gut Microbiota-Related Cellular and Molecular Mechanisms in the Progression of Nonalcoholic Fatty Liver Disease

open access: yesCells, 2021
Nonalcoholic fatty liver disease (NAFLD) is one of the most common and increasing liver diseases worldwide. NAFLD is a term that involves a variety of conditions such as fatty liver, steatohepatitis, or fibrosis. Gut microbiota and its products have been
Eunju Park   +8 more
doaj   +1 more source

Hematological Malignancies and HBV Reactivation Risk: Suggestions for Clinical Management

open access: yesViruses, 2019
It is well known that hepatitis B virus reactivation (HBVr) can occur among patients undergoing treatment for hematological malignancies (HM). The evaluation of HBVr risk in patients undergoing immunosuppressive treatments is a multidimensional process ...
Alessandra Zannella   +2 more
doaj   +1 more source

The convergent application of metabolites from Avena sativa and gut microbiota to ameliorate non-alcoholic fatty liver disease: a network pharmacology study

open access: yesJournal of Translational Medicine, 2023
Background Non-alcoholic fatty liver disease (NAFLD) is a serious public health issue globally, currently, the treatment of NAFLD lies still in the labyrinth.
Ki-Kwang Oh   +10 more
doaj   +1 more source

Gut microbiome and metabolome signatures in liver cirrhosis-related complications [PDF]

open access: yesClinical and Molecular Hepatology
Background/Aims Shifts in the gut microbiota and metabolites are interrelated with liver cirrhosis progression and complications. However, causal relationships have not been evaluated comprehensively.
Satya Priya Sharma   +19 more
doaj   +1 more source

New insight into gut microbiota-derived metabolites to enhance liver regeneration via network pharmacology study

open access: yesArtificial Cells, Nanomedicine, and Biotechnology, 2023
We intended to identify favourable metabolite(s) and pharmacological mechanism(s) of gut microbiota (GM) for liver regeneration (LR) through network pharmacology.
Ki-Kwang Oh   +18 more
doaj   +1 more source

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