Results 1 to 10 of about 1,571,974 (242)

Immunoglobulin A and liver diseases. [PDF]

Journal of Gastroenterology, 2017
Immunoglobulin A (IgA) is a major immunoglobulin isotype in the gut and plays a role in maintenance of gut homeostasis. Secretory IgA (SIgA) has multiple functions in the gut, such as to regulate microbiota composition, to protect intestinal epithelium ...
Inamine, Tatsuo, Schnabl, Bernd
core   +6 more sources

Sphingomyelinases and Liver Diseases [PDF]

Biomolecules, 2020
Sphingolipids (SLs) are critical components of membrane bilayers that play a crucial role in their physico-chemical properties. Ceramide is the prototype and most studied SL due to its role as a second messenger in the regulation of multiple signaling pathways and cellular processes.
Naroa Insausti-Urkia, Estel Solsona-Vilarrasa, Carmen Garcia-Ruiz, Jose C. Fernandez-Checa   +3 more
openaire   +4 more sources

Critical Role of microRNA-21 in the Pathogenesis of Liver Diseases [PDF]

, 2020
MicroRNAs are small non-coding RNAs that range in length from 18 to 24 nucleotides. As one of the most extensively studied microRNAs, microRNA-21 (miR-21) is highly expressed in many mammalian cell types.
Han, Sen, Kusumanchi, Praveen, Liangpunsakul, Suthat, Yang, Zhihong, Zhang, Ting   +4 more
core   +1 more source

Genome-wide and Mendelian randomisation studies of liver MRI yield insights into the pathogenesis of steatohepatitis [PDF]

, 2020
Background A non-invasive method to grade the severity of steatohepatitis and liver fibrosis is magnetic resonance imaging (MRI) based corrected T1 (cT1).
Banerjee, R, Banerjee, R, Bell, J.D., Bell, J.D., Hemingway, H., Hemingway, H., Hingorani, A.D., Hingorani, A.D., Kelly, M., Kelly, M., McGonigle, J., McGonigle, J., Neubauer, S., Neubauer, S., Nicholls, R.C., Nicholls, R.C., Parisinos, C.A., Parisinos, C.A., Patel, R.S., Patel, R.S., Thomas, E.L., Thomas, E.L., Wilman, H., Wilman, H., Yaghootkar, H., Yaghootkar, H.   +25 more
core   +3 more sources

Iron and Liver Diseases [PDF]

Canadian Journal of Gastroenterology and Hepatology, 1999
A mild to moderate iron excess is found in patients with liver diseases apparently unrelated to genetic hemochromatosis. Iron appears to affect the natural history of hepatitis C virus‐related chronic liver diseases, alcoholic liver disease and nonalcoholic steatohepatitis by leading to a more severe fibrosis and thus aiding the evolution to cirrhosis ...
S.R. Fargion, M. Mattioli, A.L. Fracanzani, G. Fiorelli   +3 more
openaire   +6 more sources

Bile Acid Receptor Therapeutics Effects on Chronic Liver Diseases [PDF]

, 2020
In the past ten years, our understanding of the importance of bile acids has expanded from fat absorption and glucose/lipid/energy homeostasis into potential therapeutic targets for amelioration of chronic cholestatic liver diseases.
Alpini, Gianfranco, Francis, Heather, Kennedy, Lindsey, Kundu, Debjyoti, Meadows, Vik   +4 more
core   +1 more source

Pediatric liver diseases: current challenges and future perspectives [PDF]

, 2015
Chronic liver diseases in children represent a rising problem with significant effects on public health. In fact, several pediatric liver diseases are precursors of adult chronic hepatopathies, cirrhosis and hepatocellular carcinoma.
Alisi, Anna, Alterio, Arianna, Della Corte, Claudia, Mosca, Antonella, Nobili, Valerio, Vania, Andrea   +5 more
core   +1 more source

Cholangiocytes: Cell transplantation [PDF]

, 2017
Background:Due to significant limitations to the access to orthotropic liver transplantation, cell therapies forliver diseases have gained large interest worldwide.Scope of review:To revise current literature dealing with cell therapy for liver diseases.
Alvaro, Domenico, Bragazzi, MARIA CONSIGLIA, Cardinale, Vincenzo, Carpino, Guido, Gaudio, Eugenio, Ridola, Lorenzo   +5 more
core   +1 more source

Hepatic stellate cells and parasite-induced liver fibrosis [PDF]

, 2010
: Fibrogenesis is a common feature of many diseases where there is severe insult to the liver. The hepatic stellate cell trans-differentiation into a myofibroblast has been identified as an important event in liver fibrogenesis and has been well ...
Allen, JT, Anthony, BJ, Li, YS, McManus, DP   +3 more
core   +2 more sources

Liver resections: complications and survival outcome [PDF]

, 2007
none1noToday, liver resection represents one of the most effective therapies in the treatment of defined liver diseases, particularly for hepatocellular carcinomas, liver metastases and tumors originating from the bile ducts.
Grazi, Gian Luca
core   +1 more source