Protein induced by vitamin K absence or antagonist-II (PIVKA-II) specifically increased in Italian hepatocellular carcinoma patients [PDF]
OBJECTIVE: As a marker for Hepatocellular Carcinoma (HCC), Protein Induced by Vitamin K Absence II (PIVKA-II) seems to be superior to alpha fetoprotein (AFP).
Anastasi, Emanuela+7 more
core +1 more source
Role of High-Mobility Group Box-1 in Liver Pathogenesis [PDF]
High-mobility group box 1 (HMGB1) is a highly abundant DNA-binding protein that can relocate to the cytosol or undergo extracellular release during cellular stress or death. HMGB1 has a functional versatility depending on its cellular location.
Huda, Nazmul+3 more
core +1 more source
Delving Deep into Liver Focal Lesion Detection: A Preliminary Study [PDF]
Hepatocellular carcinoma (HCC) is the second most frequent cause of malignancy-related death and is one of the diseases with the highest incidence in the world. Because the liver is the only organ in the human body that is supplied by two major vessels: the hepatic artery and the portal vein, various types of malignant tumors can spread from other ...
arxiv
Orthotopic liver transplantation for fulminant and subacute hepatic failure [PDF]
Fulminant and subacute hepatitis are conditions characterized by rapid liver failure, which can lead to death in 80 to more than 95% of the cases with medical supportive care only.
Iwatsuki, S, Starzl, TE, Stieber, AC
core
The pseudokinase MLKL mediates programmed hepatocellular necrosis independently of RIPK3 during hepatitis [PDF]
Although necrosis and necroinflammation are central features of many liver diseases, the role of programmed necrosis in the context of inflammation-dependent hepatocellular death remains to be fully determined.
Andreas E. Kremer+24 more
core +1 more source
Inflammasomes in liver diseases
Inflammation is a common element in the pathogenesis of most chronic liver diseases that lead to fibrosis and cirrhosis. Inflammation is characterized by activation of innate immune cells and production of pro-inflammatory cytokines IL-1α, IL-1β, and TNFα.
Szabo, Gyongyi, Csak, Timea
openaire +4 more sources
CONDITION OF INTRACARDIAC HEMODYNAMICS AND MICROCIRCULATION IN PATIENTS WITH CHRONIC ISCHEMIC HEART DISEASE AND CONCOMITANT DIFFUSE LIVER DISEASES [PDF]
Introduction. It is known that patients with ischemic heart diseases have endothelial dysfunction, but there is lack of research about microcirculation in these patients with diffuse liver diseases, especially diagnosed with digital capillaroscopy.
Dynnyk O., Marunchyn N., Mostovyi S.
core +3 more sources
Preimplantation factor (PIF) is an evolutionary conserved peptide secreted by viable embryos which promotes maternal tolerance without immune suppression. Synthetic PIF (sPIF) replicates native peptide activity.
Christopher B. O’Brien+8 more
doaj +1 more source
Image segmentation of liver stage malaria infection with spatial uncertainty sampling [PDF]
Global eradication of malaria depends on the development of drugs effective against the silent, yet obligate liver stage of the disease. The gold standard in drug development remains microscopic imaging of liver stage parasites in in vitro cell culture models.
arxiv
Comparative Study on Serum Enzyme Levels in Cirrhosis of Liver and Alcoholic Liver Disease [PDF]
Patients with chronic liver diseases are asymptomatic or have only vague non-specific symptoms. Effective medical treatments for chronic liver disease (before cirrhosis is established) are becoming increasingly available and since abnormal LFTs may be ...
Ershad, R+3 more
core +1 more source