Results 31 to 40 of about 2,424,188 (403)
Combi-Elasto Evaluation of the Degree of Liver Fibrosis in Children with Cholestatic Liver Disease
Diagnostics, 2023 Cholestatic liver disease is a common liver disease in infants and young children. Liver fibrosis is a key factor affecting the prognosis, and liver transplantation is the only treatment option for liver cirrhosis.
Rina Li +8 more
doaj +1 more source
Liver Fibrosis: Mechanistic Concepts and Therapeutic Perspectives
Cells, 2020 Liver fibrosis due to viral or metabolic chronic liver diseases is a major challenge of global health. Correlating with liver disease progression, fibrosis is a key factor for liver disease outcome and risk of hepatocellular carcinoma (HCC).
Natascha Roehlen +2 more
semanticscholar +1 more source
Nature Communications, 2021 Non-alcoholic steatohepatitis (NASH) is a leading cause of chronic liver disease that can progress to liver fibrosis. Recent clinical advance suggests a reversibility of liver fibrosis, but the cellular and molecular mechanisms underlying NASH resolution
Yuzo Koda +13 more
semanticscholar +1 more source
Biomedicines, 2022 Liver fibrosis is a key pathophysiology process in chronic liver disease. It is still unclear whether the impact of liver fibrosis is not fully realized in type 2 diabetes mellitus (T2D) patients with nonalcoholic fatty liver disease (NAFLD), and the ...
Chia-Yen Dai +4 more
doaj +1 more source
Hepatic macrophages: Key players in the development and progression of liver fibrosis
Liver international (Print), 2021 Hepatic fibrosis is a common pathological process involving persistent liver injury with various etiologies and subsequent inflammatory responses that occur in chronic liver diseases.
Da Cheng +5 more
semanticscholar +1 more source
Epigenetics and Liver Fibrosis [PDF]
Cellular and Molecular Gastroenterology and Hepatology, 2017 Liver fibrosis arises because prolonged injury combined with excessive scar deposition within hepatic parenchyma arising from overactive wound healing response mediated by activated myofibroblasts. Fibrosis is the common end point for any type of chronic liver injury including alcoholic liver disease, nonalcoholic fatty liver disease, viral hepatitis ...
Moran-Salvador E, Mann J
openaire +4 more sources
Diagnostics, 2023 (1) Background: This study aimed to correlate the indocyanine green clearance (ICG) test with histopathological grades of liver fibrosis and liver cirrhosis to assess its diagnostic accuracy in differentiating normal liver parenchyma from liver fibrosis ...
Lukas Luerken +9 more
doaj +1 more source
Mechanisms of liver fibrosis and its role in liver cancer
Experimental biology and medicine, 2020 Hepatic fibrogenesis is a pathophysiological outcome of chronic liver injury hallmarked by excessive accumulation of extracellular matrix proteins. Fibrosis is a dynamic process that involves cross-talk between parenchymal cells (hepatocytes), hepatic ...
D. Dhar +3 more
semanticscholar +1 more source
The evaluation of liver fibrosis regression in chronic hepatitis C patients after the treatment with direct-acting antiviral agents – A review of the literature [PDF]
, 2019 The second-generation of direct-acting antiviral agents are the current treatment for chronic viral hepatitis C infection. To evaluate the regression of liver fibrosis in patients receiving this therapy, liver biopsy remains the most accurate method, but
Alexescu, Teodora G +12 more
core +3 more sources
Cellular and Molecular Gastroenterology and Hepatology, 2023 Background & Aims: Liver fibrosis/cirrhosis is significant health burden worldwide, resulting in liver failure or cancer and accounting for many deaths each year.
Xiaolei Li +6 more
doaj +1 more source