Results 101 to 110 of about 311,004 (351)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Supplementary Figure 3 from Neutrophil Extracellular Traps Promote the Development and Progression of Liver Metastases after Surgical Stress

, 2023
Samer Tohme, Hamza O. Yazdani, Ahmed B. Al‐Khafaji, Alexis P. Chidi, Patricia Loughran, Kerri Mowen, Yanming Wang, Richard L. Simmons, Huang Hai, Allan Tsung   +9 more
openalex   +1 more source

A totally laparoscopic associating liver partition and portal vein ligation for staged hepatectomy assisted with radiofrequency (radiofrequency assisted liver partition with portal vein ligation) for staged liver resection [PDF]

, 2016
In order to induce liver hypertrophy to enable liver resection in patients with a small future liver remnant, various methods have been proposed in addition to portal vein embolisation.
Fajardo, A, Fang, R, Gall, TMH, Hakim, DN, Jiao, LR, Pencavel, T, Sordgren, MH   +6 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Oligometastases in pancreatic cancer (Synchronous resections of hepatic oligometastatic pancreatic cancer: Disputing a principle in a time of safe pancreatic operations in a retrospective multicenter analysis)

Annals of Gastroenterological Surgery, 2019
The aim of the present review was to analyze the current data on surgery of synchronous liver metastases in pancreatic ductal adenocarcinoma (PDAC) in curative intent.
Nina Voss, Jakob R. Izbicki, Michael F. Nentwich   +2 more
doaj   +1 more source

Intraoperative Ultrasound as a Screening Modality for the Detection of Liver Metastases during Resection of Primary Colorectal Cancer - A Systematic Review

Ultrasound International Open, 2017
Colorectal cancer (CRC) is one of the most common cancer diseases worldwide. One in 4 patients with CRC will have a disseminated disease at the time of diagnosis and often in the form of synchronous liver metastases.
Signe Bremholm Ellebæk, Claus Wilki Fristrup, Michael Bau Mortensen   +2 more
doaj   +1 more source

Supplementary Figures S1-S5 from Redirecting Transport of Nanoparticle Albumin-Bound Paclitaxel to Macrophages Enhances Therapeutic Efficacy against Liver Metastases

, 2023
Tomonori Tanei, Fransisca Leonard, Xuewu Liu, Jenolyn F. Alexander, Yuki Saito, Mauro Ferrari, Biana Godin, Kenji Yokoi   +7 more
openalex   +2 more sources

Robotic hand port assisted resection of liver and peritoneal metastases in patient with high-grade myxoid liposarcoma [PDF]

, 2021
K. Ginting, Shyam Allamaneni
openalex   +1 more source

Treatment of fibrolamellar hepatoma with partial or total hepatectomy and transplantation of the liver [PDF]

, 1986
Fourteen patients with fibrolamellar hepatoma were treated with radical excision. In eight, a subtotal hepatic resection was performed from 16 months to more than 16 years ago.
Farhi, DC, Iwatsuki, S, Nalesnik, MA, Shaw, BW, Starzl, TE, Van Thiel, DH   +5 more
core