Results 151 to 160 of about 35,405 (287)

Mechano-modulatory synthetic niches for liver organoid derivation [PDF]

open access: gold, 2020
Giovanni Sorrentino   +6 more
openalex   +1 more source

BLOC: Buildable and Linkable Organ on a Chip

open access: yesAdvanced Materials Technologies, EarlyView.
We developed a “Buildable and Linkable Organ on a Chip” (BLOC) that can construct diverse microphysiological systems (MPSs). The BLOC is standardized to the same size and has one of the functions of “Culture,” “Control,” or “Analysis.” Users can freely configure various MPSs, including developing perfusion, cytotoxicity analysis, and biochemical ...
Yusuke Kimura   +7 more
wiley   +1 more source

Hydrogel Confinement Strategies for 3D Cell Culture in Microfluidic Systems

open access: yesAdvanced Materials Technologies, EarlyView.
Hydrogel confinement structures are key to organizing 3D cell cultures in microfluidic devices. This review classifies five structural strategies (micropillar, phaseguide, porous membrane, stepped‐height, and support‐free) and examines their trade‐offs alongside fabrication methods.
Soohyun Kim, Min Seok Lee, Sung Kyun Lee
wiley   +1 more source

High‐Throughput Formation of Pre‐Vascularized hiPSC‐Derived Hepatobiliary Organoids on a Chip via Nonparenchymal Cell Grafting

open access: yesAdvanced Science
Liver organoids have been increasingly adopted as a critical in vitro model to study liver development and diseases. However, the pre‐vascularization of liver organoids without affecting liver parenchymal specification remains a long‐lasting challenge ...
Han Fan   +12 more
doaj   +1 more source

Disease Modeling on Tumor Organoids Implicates AURKA as a Therapeutic Target in Liver Metastatic Colorectal Cancer

open access: gold, 2021
Sophie Luise Boos   +14 more
openalex   +1 more source

Engineered Microfluidic Organoid Systems: New Paradigms for Menopause Mechanism Research and Personalized Medicine

open access: yesAdvanced Materials Technologies, EarlyView.
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang   +4 more
wiley   +1 more source

Human Liver Organoids as a Patient-derived Model for HBV Infection and Cellular Response [PDF]

open access: gold, 2022
Chuan Kok Lim   +13 more
openalex   +1 more source

Biohybrid Actuators in Compact Arrangement with Embedded X Electrode

open access: yesAdvanced Robotics Research, EarlyView.
Selective control of multimuscle biohybrid actuators is crucial for achieving complex movements of biohybrid robots. In this study, embedded X electrodes are fabricated to selectively control multiple muscles, realizing the robotic finger's bidirectional movements.
Tingyu Li, Minghao Nie, Shoji Takeuchi
wiley   +1 more source

Human iPSC-Derived Posterior Gut Progenitors Are Expandable and Capable of Forming Gut and Liver Organoids [PDF]

open access: gold, 2018
Ranran Zhang   +8 more
openalex   +1 more source

Nanomaterial‐Based Muscle Cell/Neural Tissue Biohybrid Robots: From Actuation to Biomedical Applications

open access: yesAdvanced Robotics Research, EarlyView.
Muscle cell‐based biohybrid robot using nanomaterials for function enhancement and neural function for biomedical applications. Biohybrid robotics, an emerging field combining biological tissues with artificial systems, has made significant progress in developing various biohybrid constructs, including muscle‐cell‐driven biorobots and microbots.
Minkyu Shin   +4 more
wiley   +1 more source

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